Recompadrol's PPAR-Alpha agnostic activity

[mr.cooper69]

It works very very well for me, possibly better than anything other fat loss product I've tried. I've managed to drop to sub 10% without too much effort when using it. Maybe its the combination of its PPAR activity combined with the an increase fat burning enzymes.

http://www.bodybuilding.com/fun/beast21.htm

Oh, I have no doubt that it's effective for fat loss. Its inhibition of arachidonic acid metabolism and potential downstream effects on hypertrophy and muscle fullness is what deters me from using it.

[Whacked]

Well, thats what X-gels are for

Oh, I have no doubt that it's effective for fat loss. Its inhibition of arachidonic acid metabolism and potential downstream effects on hypertrophy and muscle fullness is what deters me from using it.

[MidwestBeast]

Oh, I have no doubt that it's effective for fat loss. Its inhibition of arachidonic acid metabolism and potential downstream effects on hypertrophy and muscle fullness is what deters me from using it.

Are those short term effects? I.e. if one were to use seaming for a brief cut and then cycle onto ArA coming off to combat any issues?

[saggy321]

Interesting question. The longest I've used it was for 3 months and I managed to drop to 8-9% without massively changing my diet and doing no cardio. It seriously was a breeze. I never felt I suffered any muscle loss nor did it seemingly effect muscle fullness although I wasn't measuring this. I've never tried to put on muscle whilst taking it, so I can't comment on that.

Mr Coop, is there anything you aware of that could elicit a similar effect?

[saggy321]

Well, thats what X-gels are for

I've just asked a UK supplier if they are going to stack it. The good news is they said yes. The bad news, it won't be for a few weeks as they recently received an order.

[mr.cooper69]

Are those short term effects? I.e. if one were to use seaming for a brief cut and then cycle onto ArA coming off to combat any issues?

It would only matter while you're using the sesamin.

Interesting question. The longest I've used it was for 3 months and I managed to drop to 8-9% without massively changing my diet and doing no cardio. It seriously was a breeze. I never felt I suffered any muscle loss nor did it seemingly effect muscle fullness although I wasn't measuring this. I've never tried to put on muscle whilst taking it, so I can't comment on that.

Mr Coop, is there anything you aware of that could elicit a similar effect?

TTA

[Whacked]

Interesting question. The longest I've used it was for 3 months and I managed to drop to 8-9% without massively changing my diet and doing no cardio. It seriously was a breeze. I never felt I suffered any muscle loss nor did it seemingly effect muscle fullness although I wasn't measuring this. I've never tried to put on muscle whilst taking it, so I can't comment on that.

Mr Coop, is there anything you aware of that could elicit a similar effect?

How much were you using?

I've just asked a UK supplier if they are going to stack it. The good news is they said yes. The bad news, it won't be for a few weeks as they recently received an order.

If you cant wait, try X-Factor from MM

[MAxximal]

I might be able to find the powdered sesamin supplier that we used for Phenogen way back when. Hopefully the price has come down a lot.

Avant's Sesathin FTW!!

Sent from my Inspire 4G using Am.com

[Geoforce]

Oh, I have no doubt that it's effective for fat loss. Its inhibition of arachidonic acid metabolism and potential downstream effects on hypertrophy and muscle fullness is what deters me from using it.

My main problem with Sesamin (and I know I'm not the only one that had this issue) was it completely trashed my libido. I've taken a whole hell of a lot of different supplements over the years and this is the only thing that had that type of effect on me. I ran the bottle out (been a long damn time since I took it), but my GF wasn't a happy camper during the time.

[saggy321]

How much were you using?



If you cant wait, try X-Factor from MM

I was using 1000 - 1500 mg a day.

[Whacked]

yes, that as a well-known hghly reported side

never happened to me

My main problem with Sesamin (and I know I'm not the only one that had this issue) was it completely trashed my libido. I've taken a whole hell of a lot of different supplements over the years and this is the only thing that had that type of effect on me. I ran the bottle out (been a long damn time since I took it), but my GF wasn't a happy camper during the time.

[dsade]

yes, that as a well-known hghly reported side

never happened to me

Me either...not with the Avant stuff, and i took ridiculously high dosages.

[saggy321]

Isn't the Avant stuff discontinued.

[Royd The Noyd]

Relevant to Sesamin users... New one :

Combined effect of sesamin and α-lipoic acid on hepatic fatty acid metabolism in rats.

Ide T, et al. Show all

Eur J Nutr. 2012 Jun 30. [Epub ahead of print]

Department of Food and Nutrition, Faculty of Human Life, Jumonji University, 2-1-28 Sugasawa, Niiza, Saitama, 352-8510, Japan, t-ide@jumonji-u.ac.jp.

Abstract PURPOSE: Dietary sesamin (1:1 mixture of sesamin and episesamin) decreases fatty acid synthesis but increases fatty acid oxidation in rat liver. Dietary α-lipoic acid lowers hepatic fatty acid synthesis. These changes can account for the serum lipid-lowering effect of sesamin and α-lipoic acid. It is expected that the combination of these compounds in the diet potentially ameliorates lipid metabolism more than the individual compounds. We therefore studied the combined effect of sesamin and α-lipoic acid on lipid metabolism in rats.

METHODS: Male Sprague-Dawley rats were fed diets supplemented with 0 or 2 g/kg sesamin and containing 0 or 2.5 g/kg α-lipoic acid for 22 days.

RESULTS AND CONCLUSIONS: Sesamin and α-lipoic acid decreased serum lipid concentrations and the combination of these compounds further decreased the parameters in an additive fashion. These compounds reduced the hepatic concentration of triacylglycerol, the lignan being less effective in decreasing this value. The combination failed to cause a stronger decrease in hepatic triacylglycerol concentration. The combination of sesamin and α-lipoic acid decreased the activity and mRNA levels of hepatic lipogenic enzymes in an additive fashion. Sesamin strongly increased the parameters of hepatic fatty acid oxidation enzymes. α-Lipoic acid antagonized the stimulating effect of sesamin of fatty acid oxidation through reductions in the activity of some fatty acid oxidation enzymes and carnitine concentration in the liver. This may account for the failure to observe strong reductions in hepatic triacylglycerol concentration in rats given a diet containing both sesamin and α-lipoic acid.

PMID 22752262 [PubMed - as supplied by publisher

[EBF Inc]

Love the science.

I am looking into various options for new product based on what everyone wants to see

[Geoforce]

yes, that as a well-known hghly reported side

never happened to me

Actually it happened to me less with Avant's Sesathin than with a company who shall remain nameless stuff.

Anywho, I was one of the unfortunate ones.

[dsade]

Actually it happened to me less with Avant's Sesathin than with a company who shall remain nameless stuff.

Anywho, I was one of the unfortunate ones.

It took me MONTHS to find a company willing to custom make the Sesathin raws for us...but it was worth it.

[saggy321]

Is Sesathin still available?

[Whacked]

Nope

[saggy321]

Dang...I can't believe only one company sells sesamin!