N-methyl-D-aspartic acid (NMDA) Read before supplementing
- 03-21-2012, 11:56 PM
- 03-22-2012, 09:35 AM
Originally Posted by Mission1
03-22-2012, 10:56 PM
Dude, I really don't even wanna give you a hard time right now but I have to call out bad science when I see it. That's not what this board is about, go run that kinda game to the 14 year olds on bodybuilding.com
First off, you're saying that NMDA isn't excitotoxic at all and you back that up with a study which measures the effect of creatine on NMDA INDUCED EXCITOTOXICTY. How ironic can you get? Unless you have documentation on their methodology showing that they directly injected the NMDA, this abstract is making a case against your argument, if anything.
Second, you said excitotoxicity was "basically non-existant" with the coadministration of creatine and niacin. Here's the actual graph from your study showing the effects of creatine and niacin against the control on NMDA induced excitotoxicity http://ars.sciencedirect.com/content...020382-gr2.gif
What does that reduction work out to? maybe 20-30% reduction vs control? Is that really your definition of "basically non-existant" bro?
Listen kids, not everyone on these boards has the time to decipher medical journals, that's why they come here for advice. It ruins the whole principle of these boards when someone tries to throw studies around and totally twist them around because the lay-person cant understand them. Let me take all of the science mumbo jumbo out of the equation here and simplify the argument vaughn is trying to make right now...
In a nutshell, his post is saying..."Our product isnt poisionous to your brain because there's a study that shows when you take creatine and niacin, it makes it less 30 percent less poisionous to your brain. My product is meant to be injested orally, while the abstract I provided doesn't specificy how it was given to the test subjects which makes it completely irrelevant, if not contrary to my argument altogether."
03-22-2012, 11:03 PM
03-22-2012, 11:08 PM
What degree does Vaughn have in nutritional science? I know... Nmda for dummies. He'll do anything to sell a bottles of intimidate or is called placebodate. Hey free bottles of air to first 50!!!!!! Sell sell sell.Originally Posted by J19891
03-23-2012, 02:01 AM
iForce Nutrition Online Representative Manager
iTrain. iCompete. iDominate…iForce!
03-23-2012, 02:30 AM
03-23-2012, 05:53 AM
03-23-2012, 08:14 AM
That's because some of these supplement company reps not gonna mention any names...... Vaughn......oops........feed on the innocent barely 18 and try to shrink their testicles to meet their criteria as a potential customer and try to suck them. We don't sell steroids anymore but try this it's a 100% better I guarantee it. Ugh I did read that it was better...... Maybe PA said so. Anyway ugh take this and then if you can't sleep take zma and then take it earlier in the day.... Ugh maybe now you can stack it with test v2. I promise.Originally Posted by J19891
03-23-2012, 11:51 AM
03-23-2012, 12:00 PM
03-23-2012, 02:19 PM
Broscience is sadly kind on the vast majority of health and fitness boards.
03-23-2012, 03:14 PM
I hope I don't sound ignorant but oh well. Broscience is what I go by. Majority of the "supplements" we take is not going to have real scientific studies to back it up. Scientific studies don't mean much to me anyway, I'm not a scientist so I don't understand half the crap their talking about. Plus people can make a study say what they want it to based on agenda so what good are they? I want real life people "bros" telling me what they experienced taking a product. How it affected them, what sides, if it worked. Broscience is the tried and true method, thats real life scientific studies boys.
03-23-2012, 03:45 PM
Broscience, on the other hand, is where people attempt to use science or scientific terms to make a statement, good or bad, about a product or substance but aren't applying the scientific method correctly.
If everyone on these boards told you that d-alpha supplement of the week had no research to back it up, but I told you that it took my bench press up 20 lbs, that's anecdotal evidence, not broscience.
If I tell you that creatine works by bumping up your testoserone levels with ammonia, quarks and quantum muscle fiber enhancers, that's bro science.
03-23-2012, 04:07 PM
The anecdotal stuff means little to me. Lots of people claiming to love things that did not produce a different result than could be explained by proper training/dieting. Not to mention a lot of people are straight up dishonest. I keep seeing bloods posted about a test booster from someone secretly on TRT -- wtf?
03-24-2012, 12:39 AM
it is a rather safe supplement, William Llewellyn and I have been looking into it for quite some time.
03-24-2012, 04:32 PM
03-24-2012, 08:09 PM
08-06-2013, 10:49 AM
ok new to this forum but I've taken DAA for 30 days and now pretty close to completing first bottle of NMDA. So i read this thread and am still confused. is it safe, not safe, toxic, not toxic? am i just better off taking DAA ? I'll tell you where Im leaning after reading all this; back to DAA.
08-06-2013, 11:26 AM
This should be good. Something akin to a group of 9 year olds discussing the intricacies of quantum physics while hopped up on candy.
08-06-2013, 11:36 AM
08-06-2013, 02:22 PM
Intimidate SRT has gotten rave reviews from day one and will continue to do so! NMDA + a potent AI = win!
Hi-Tech Pharmaceuticals Representative Manager
08-06-2013, 04:55 PM
08-06-2013, 05:32 PM
I tend to side with Coop on this. You're not likely to achieve blood levels of DAA or NMDA that will be excitotoxic. Delving into anecdotal land, I think you'd crap yourself silly trying to mega dose DAA and if excitotoxic effects were happening, they would likely be evident with some sort of symptom...either physically expressed or a decline in mental function. DAA has been on the shelves for awhile now.
I most certainly pay attention to the anecdotal since 99% of the supplements we use in this community are nowhere near what I would call "rigorously studied". We are simply too impatient to wait a lifetime until all the results are in..which is bad, but then the safety record of most supplements is pretty darn good.
08-06-2013, 06:17 PM
08-06-2013, 06:57 PM
08-06-2013, 07:03 PM
I will co-sign whatever the man with a PhD in neuroscience and is currently active in the field, says about it
"The only good is knowledge and the only evil is ignorance." - Socrates
08-06-2013, 07:08 PM
08-06-2013, 07:12 PM
08-06-2013, 07:16 PM
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