amino receptors

Page 1 of 2 12 Last
  1. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    I've always been taught to take aminos seperately on an empty stomach to make the most of the limited number of receptors. It makes sense that you'd want the aminos that cost so much money and serve very specific purposes to not have to compete with generic dietary protein,, or even with other supplemental aminos ..... the thing is I rarely, if ever, hear this mentioned on here .... is this not common knowledge or do people know of research indicating this isn't as important as I've been led to believe?

  2. Professional Member
    VaughnTrue's Avatar
    Join Date
    Jun 2007
    Posts
    3,872
    Rep Power
    1018892
    Level
    55
    Lv. Percent
    87.9%
    Achievements Activity ProPosting Pro

    no such thing as amino receptors.
  3. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by VaughnTrue
    no such thing as amino receptors.
    Protein receptors are amino receptors ....
    •   
       

  4. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by grngoloco

    Protein receptors are amino receptors ....
    Which is why taking aminos along with protein shakes is a bad idea, from what I understand
  5. Diamond Member
    mr.cooper69's Avatar
    Join Date
    Feb 2011
    Posts
    10,686
    Rep Power
    6897332
    Level
    99
    Lv. Percent
    73.61%
    Achievements Activity AuthorityActivity ProActivity VeteranActivity RoyaltyPosting Pro

    No such thing...
  6. Professional Member
    VaughnTrue's Avatar
    Join Date
    Jun 2007
    Posts
    3,872
    Rep Power
    1018892
    Level
    55
    Lv. Percent
    87.9%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by grngoloco View Post
    Protein receptors are amino receptors ....
    No such thing as protein receptors either
  7. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    Really??? I remember reading this a long while back,,,, what am I thinking of? I remember reading to take aminos on empty stomach to prevent receptor competition?????
  8. therealest77
    Guest
    therealest77's Avatar

    Quote Originally Posted by grngoloco

    Protein receptors are amino receptors ....
    Did u day protein receptors??
  9. therealest77
    Guest
    therealest77's Avatar

    Quote Originally Posted by grngoloco

    Protein receptors are amino receptors ....
    Correction; did u say "protein receptors"?
  10. Professional Member
    chocolatemilk's Avatar
    Stats
    5'9"  207 lbs.
    Join Date
    Apr 2010
    Posts
    3,804
    Rep Power
    9976
    Level
    43
    Lv. Percent
    63.66%
    Achievements Activity ProPosting Pro

    If you want to be technical all receptors and enzymes are polypedptides so they are "protein receptors" and ligand binding occurs between amino acid residues of the ligand and receptor... although I doubt that's what he means lol
  11. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    Maybe the term receptor isn't correct,,, but surely there are transports that carry the proteins and/or aminos through the cellular walls... forgive my lack of terminology,, but I believe the concept is the same
  12. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by grngoloco
    Maybe the term receptor isn't correct,,, but surely there are transports that carry the proteins and/or aminos through the cellular walls... forgive my lack of terminology,, but I believe the concept is the same
    Try not to attack my lack of actual biochemistry knowledge,,, but aren't you supposed to take aminos on an empty stomach,,, and if so, why is that!?
  13. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro
  14. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    It is my understanding that bcaa's are the only aminos that need to be taken with food,,, something about needing insulin,,, all other aminos should be taken alone on empty stomachs,,, which goes against the marketing and packaging of most every supp company's "amino complexes"........ if this is true,, I can certainly understand why supp companies and their reps would want to argue this
  15. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    Bump for some real conversation regarding the need to take aminos on an empty stomach,,,, for the record,, I totally disagree with those of you that said there are not amino acid receptors,,, there are entire studies and books written about them
  16. New Member
    3utcher's Avatar
    Join Date
    Mar 2011
    Posts
    217
    Rep Power
    777
    Level
    12
    Lv. Percent
    51.7%

    there's no need to take them on an empty stomach.
    there's no need to take them.
  17. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by 3utcher
    there's no need to take them on an empty stomach.
    there's no need to take them.
    Do your research,,, aminos aren't for people that need them,, but for people that want more!!
  18. New Member
    3utcher's Avatar
    Join Date
    Mar 2011
    Posts
    217
    Rep Power
    777
    Level
    12
    Lv. Percent
    51.7%

    so you negged me because you still think that taking FF aminos is better than protein ?

    lolwtfbbq
  19. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by 3utcher
    so you negged me because you still think that taking FF aminos is better than protein ?

    lolwtfbbq
    First of all,, nowhere in this very short thread did I mention anything about aminos being "better"

    Second of all I negged you for attempting to disrupt the purpose of my thread by interjecting an "opinion," not based on facts, about something that had nothing to do with the proposed question!!
  20. Board Moderator
    Unbreakable
    David Dunn's Avatar
    Join Date
    Mar 2003
    Age
    49
    Posts
    11,823
    Rep Power
    1317972

    Quote Originally Posted by grngoloco View Post
    Bump for some real conversation regarding the need to take aminos on an empty stomach,,,, for the record,, I totally disagree with those of you that said there are not amino acid receptors,,, there are entire studies and books written about them

    Quote Originally Posted by grngoloco View Post
    Do your research,,, aminos aren't for people that need them,, but for people that want more!!
    Until now all you have done is regurgitate something you think you recall you think you read or someone told you.

    Walk the talk - where is your research to back this up with the "entire studies and books written about them?" Right now all you have brought is your opinion as well.
  21. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by David Dunn

    Until now all you have done is regurgitate something you think you recall you think you read or someone told you.

    Walk the talk - where is your research to back this up with the "entire studies and books written about them?" Right now all you have brought is your opinion as well.
    I don't know much about amino acid receptors,, which is why I proposed this thread... but I do know they exist ...
    http://m.pnas.org/content/90/20/9576.short
  22. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro
  23. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro
  24. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro
  25. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    "Amino Acid Receptor Research"
    By Benjamin F. Paley
  26. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    All these articles mention taking on an empty stomach to prevent competition.... I want to know more about this.... not looking to pick some sort of retarded online fight with people ... lmao!!
  27. Board Moderator
    Unbreakable
    David Dunn's Avatar
    Join Date
    Mar 2003
    Age
    49
    Posts
    11,823
    Rep Power
    1317972

    It appears that this receptor you are talking about is post first pass through the liver and has absolutely nothing to do with how you take them - empty stomach or not - as they don't compete for absoption in your digestion aside from the fact that BCAA are predigested and are absorbed without having to go through the digestion process that protein powders or whole foods do. The receptor issue is a physiological and nuerological issue and not dependent upon the timing or state of your stomach at the time of consumption but rather what happens with them after first pass liver processing.

    Based on my cursory review of some of that literature it is JMHO
  28. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by David Dunn
    It appears that this receptor you are talking about is post first pass through the liver and has absolutely nothing to do with how you take them - empty stomach or not - as they don't compete for absoption in your digestion aside from the fact that BCAA are predigested and are absorbed without having to go through the digestion process that protein powders or whole foods do. The receptor issue is a physiological and nuerological isse and not dependent upon the timing or state of your stomach at the time of consumption but rather what happens with them after first pass liver processing.

    Based on my cursory review of some of that literature it is JMHO
    For argument sake,, why does my glutamine and arginine both say to take on an empty stomach
  29. Senior Member
    bigdavid's Avatar
    Stats
    6'2"  250 lbs.
    Join Date
    Jan 2011
    Posts
    2,274
    Rep Power
    19621
    Level
    34
    Lv. Percent
    98.14%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by grngoloco View Post
    For argument sake,, why does my glutamine and arginine both say to take on an empty stomach
    He is saying the "receptor" issue has to do with the aminos AFTER they enter the body. What you are talking about is competition for entry through the intestinal lining BEFORE the aminos enter the body.
  30. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by bigdavid

    He is saying the "receptor" issue has to do with the aminos AFTER they enter the body. What you are talking about is competition for entry through the intestinal lining BEFORE the aminos enter the body.
    I'm talking about wanting to get the most bang for my buck .... lol... like I said,, if I already knew all about receptors, why would I post a log asking about them? Haha!?
  31. Senior Member
    bigdavid's Avatar
    Stats
    6'2"  250 lbs.
    Join Date
    Jan 2011
    Posts
    2,274
    Rep Power
    19621
    Level
    34
    Lv. Percent
    98.14%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by grngoloco View Post
    I'm talking about wanting to get the most bang for my buck .... lol... like I said,, if I already knew all about receptors, why would I post a log asking about them? Haha!?
    I think there may be a semantics issue here. You are talking about competition for transport proteins on the lining of the intestine I think you are calling them receptors, though.
  32. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    Crystaline free form amino acids do not need to be digested,, so where does that play into the pre and post digestion competition for absorption??
  33. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by bigdavid

    I think there may be a semantics issue here. You are talking about competition for transport proteins on the lining of the intestine I think you are calling them receptors, though.
    I think you may be right about that,,, like I said early in the thread,, I wasn't sure the term "receptor" was the correct term
  34. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by bigdavid

    I think there may be a semantics issue here. You are talking about competition for transport proteins on the lining of the intestine I think you are calling them receptors, though.
    With that in mind,,, how important is the necessity to take aminos individually on an empty stomach
  35. Senior Member
    bigdavid's Avatar
    Stats
    6'2"  250 lbs.
    Join Date
    Jan 2011
    Posts
    2,274
    Rep Power
    19621
    Level
    34
    Lv. Percent
    98.14%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by grngoloco View Post
    Crystaline free form amino acids do not need to be digested,, so where does that play into the pre and post digestion competition for absorption??
    Some amino acids are charged thus they cannot just diffuse through the intestinal cells to enter the body they have to be transported across. Since there is a limited number of transporters there will be competition if you take them with a whole protein source because the individual amino acids that are being broken apart from the whole protein source will be competing for use of these transporters. The process of "digestion" where you break apart the protein into individual amino acids with stomach acid and then with enzymes secreted from the pancreas or on the intestinal cell lining is a different process that happens before they are absorbed. The competition is not with digestion, since free form AA's are already in their broken down form. The competition is in the use of the transport proteins to get the amino acids in the body.
  36. Senior Member
    bigdavid's Avatar
    Stats
    6'2"  250 lbs.
    Join Date
    Jan 2011
    Posts
    2,274
    Rep Power
    19621
    Level
    34
    Lv. Percent
    98.14%
    Achievements Activity ProPosting Pro

    So the thought is take the free form aminos on an empty stomach to avoid competition from the aminos that will come from the whole protein source.
  37. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by bigdavid
    So the thought is take the free form aminos on an empty stomach to avoid competition from the aminos that will come from the whole protein source.
    What about ff aminos competing with each other,, even when taken on an empty stomach,, that's my main concern and the crux of what I was originally trying to get to
  38. Board Moderator
    Unbreakable
    David Dunn's Avatar
    Join Date
    Mar 2003
    Age
    49
    Posts
    11,823
    Rep Power
    1317972

    Quote Originally Posted by grngoloco View Post
    Crystaline free form amino acids do not need to be digested,, so where does that play into the pre and post digestion competition for absorption??
    You are over analyzing this. Predigested BCAA are quickly absorbed because they do not need to be digested. They then go through the liver and then the "receptors" come into play. The receptor has nothing to do with digestion or absorption. It is after absorption and processed through the liver that receptors are an issue. This is the same process for protein powdersa and whole for protein except the are slower digested in the digestive tract before they go through the same process in the liver.

    Now greater amounts of various forms or proteins, EAA or BCAA consumed may influence the amount available to pass through the liver increasing what is available for receptors after passing through the liver.
  39. Senior Member
    bigdavid's Avatar
    Stats
    6'2"  250 lbs.
    Join Date
    Jan 2011
    Posts
    2,274
    Rep Power
    19621
    Level
    34
    Lv. Percent
    98.14%
    Achievements Activity ProPosting Pro

    If you are taking a limited dose of more than one amino there shouldnt be an issue. It is not like you are taking over 30 grams of ff AAs
  40. Senior Member
    grngoloco's Avatar
    Stats
    6'1"  235 lbs.
    Join Date
    Oct 2011
    Posts
    1,576
    Rep Power
    1922
    Level
    30
    Lv. Percent
    37.89%
    Achievements Activity ProPosting Pro

    Quote Originally Posted by David Dunn
    You are over analyzing this. Predigested BCAA are quickly absorbed because they do not need to be digested. They then go through the liver and then the "receptors" come into play. The receptor has nothing to do with digestion or absorption. It is after absorption and processed through the liver that receptors are an issue. This is the same process for protein powdersa and whole for protein except the are slower digested in the digestive tract before they go through the same process in the liver.

    Now greater amounts of various forms or proteins, EAA or BCAA consumed may influence the amount available to pass through the liver increasing what is available for receptors after passing through the liver.
    Ok,, it is my understanding that bcaa's do not act the same way upon ingestion as, let's say, arginine, ornithine or glutamine
  

  
 

Similar Forum Threads

  1. For Sale: WTS - Dymatize - Advanced Amino (Amino Acids)
    By hardknock in forum Supplement Auction
    Replies: 0
    Last Post: 11-14-2010, 03:05 AM
  2. cytomel and receptors
    By tsantsa in forum Supplements
    Replies: 3
    Last Post: 07-26-2010, 06:43 PM
  3. Replies: 0
    Last Post: 08-22-2009, 08:34 AM
  4. For Sale: Wanted to buy or trade Amino's (Amino Acids)
    By Kristofer68SS in forum Supplement Auction
    Replies: 0
    Last Post: 11-23-2008, 06:57 PM
  5. Androgen Receptors
    By Buffgammaman in forum Anabolics
    Replies: 6
    Last Post: 08-22-2008, 07:58 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
Log in
Log in