I read bcaa's need insulin for absorption,,, not sure how or why...Originally Posted by David Dunn
Specifically,, low insulin inhibits ansorption into muscle tissueOriginally Posted by grngoloco
That is different than (digestive) absorption.
Insulin (glycogen) shuttles aminos into the muscle after absorption. But there is also a thing called glycogenesis where in the body will convert protein/aminos into glycogen in its absence.
"He will turn the hearts of the fathers to their children, and the hearts of the children to their fathers"
LOL... Like I said, I don't post queries about stuff I already know!Originally Posted by David Dunn
Well,, I'll keep taking my aminos individually on an empty stomach,as best I can... wherever it occurs,, there definitely seems to be evidence of competition,, nothing makes me more mad than expensive toilet water
Dude, these receptors you are referring to are not broad-spectrum amino acid receptors for dietary protein that you ingest. They are specific receptors for metabolic processes in the body. I'm sorry, but you can't cite activity at thereceptor and thus psotulate that there are "amino acid receptors." There aren't.
Let me clear up what's happening in the small intestine. After peptide cleavage at a variety of primary levels (pepsin in the stomach, pancreatic release of trypsin/chymotrypsin in the duodenum), we have a bunch of small di and tri peptides. From here, these peptides are further cleaved into individual amino acids at the level of the microvilli by enzymes that we will refer to collectively as "brush-border enzymes" for simplicity. However, di/tri peptides can also enter the enterocyte, at which point enzymes within the cell will reduce them to amino acids. No peptides will enter the bloodstream following intestinal absorption; one way or another, they will be individual amino acids.
Here's a nice image depicting this:
And here's a description from one of my textbooks showing how exactly amino acids are absorbed. I had a much better textbook with an image showing means of absorption for each individual EAA, but I'm on break and don't have access to it. You can PM me in a week if you're still interested.
I think I was talking about transporters and not receptors,, relax a bit,, I'm not as biochemistry educated as a lot of y'allOriginally Posted by mr.cooper69
Thanks for all the input,,, I came to AM to learn, not put my vast knowledge on display,,, I really do take everything people tell me and put it to further research,,, again, thanks
Mainly asking about the importance of taking aminos individually and separately .... how important is it?
Been on the go all day,, haven't had time to look into the responses I've gotten,, but I will
Why do my arginine and glutamine bottles say to take on empty stomach?Originally Posted by mr.cooper69
lol cooper I think we used that same book for one of my nutrition classes
I never worried about NO with arginine,,, I was under the impression if taken at very high doses in a 2:1 ratio with ornithine it will stimulate gh releaseOriginally Posted by mr.cooper69