I have religiously experimented with tons of transdermal fat loss creams/gels on the market since 2002. Avants , Yohimburn from AFstore, Pa's Skulpt, ALRI's DMSO based version Primordials Dermatherm, as of recent.
IMO -- THEY WORK.
I ONLY use them when dieting for a contest and BF% gets annoyingly stubborn the lower in BF you get. Homeostasis wants to reign supreme. I am talking LEAN lean here,,,, single digits (true) to be exact. When most body parts are "in" yet glutes tie-ins, lower/corner of back/kidney area and for some men lower abs.
Genetically either men have stubborn low backs but abs come in nice or vice versa. For me it is corner back/kidney area (God I hate it) and the times I incinerated that last bit of fat WITHOUT a topical, I incinerated inches on my arms, chest etc.... in the process. Remember the body does not "selectively" choose where fats burns from that is why a topical would HELP this situation. Poster above mentioned this briefly.
I know it is a blood flow, temperature issue and infiltrating something that ignites heat and ultimately blood flow will increase fat to be oxidized from that area. Capsaizen, , aminophylline, yohimbineHCL, caffeine, nicotine, etc....I have found all great ingredients for inducing this response.
So when I did incorporate the above, I did NOT lose inches from arms, thighs etc in order to burn that bull**** low back lard. I maintained a much heaver and "fuller" stage weight.
My advice is to stress ALL facets first before you revert to that. It will be extremely hard if you do not have elite genetics to get into true single digits without being hormonally assisted. But if you get there, THESE DO WORK.