what sort of health benefits from alcar?......
Acetyl-l-carnitine is a nootropic and amino acid that has multiple benefits including being cardioprotective and helping to maintain healthy blood lipid profiles. It has also been shown to help accelerate recovery after exercise. Other benefits include increasing insulin response, it’s neuroprotective, and an antioxidant.
Volek JS, Kraemer WJ, Rubin MR, Gomez AL, Ratamess NA, Gaynor P. L-carnitine l-tartrate supplementation favorable affects markers of recovery from exercise stress. Am J Physiol Endocrinol Metab 2002;282(2):E474-E482.
Al-Majed AA, Sayed-Ahmed MM, Al-Omar FA, et al. Carnitine esters prevent oxidative stress damage and energy depletion following transient forebrain ischaemia in the rat hippocampus. Clinical and Experimental Pharmacology & Physiology 2006;33(8):725–33. Available at:
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10.1111/j.1440-1681.2006.04425.x.
PMID 16895547.
Barhwal K, Hota SK, Jain V, Prasad D, Singh SB, Ilavazhagan G. Acetyl-l-carnitine (ALCAR) prevents hypobaric hypoxia-induced spatial memory impairment through extracellular related kinase-mediated nuclear factor erythroid 2-related factor 2 phosphorylation. Neuroscience 2009;161(2):501–14. Available at:
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10.1016/j.neuroscience.2009.02.086.
PMID 19318118.
Ruggenenti P, Cattaneo D, Loriga G, et al. Ameliorating hypertension and insulin resistance in subjects at increased cardiovascular risk: effects of acetyl-L-carnitine therapy. Hypertension 2009;54(3):567–74. Available at:
doi:
10.1161/HYPERTENSIONAHA.109.132522.
PMID 19620516.
Zhang Z, Zhao M, Li Q, Zhao H, Wang J, Li Y. Acetyl-l-carnitine inhibits TNF-alpha-induced insulin resistance via AMPK pathway in rat skeletal muscle cells. FEBS Letters 2009;583(2):470–4. Available at:
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10.1016/j.febslet.2008.12.053.
PMID 19121314.
