what you want is just enough to be used for fat oxidation and no more where it would increase the chance to lower t3 levels.
that why i use no more then 500-2000mg per day.
Thanks for posting those studies, after reading those and a couple others, my general understanding is that carnitines use in hyperthyroidism is through two different mechanisms. Oral carnitine administration will reduce the symptoms (not necessarily the actual disease) of hyperthyroidism by replenishing the bodies carnitine stores once they have been depleted by excess circulating T3/T4. Beyond that it seems carnitine has a slight regulatory effect on T3/T4 entrance into the cell nucleus and/or cytoplasm (peripheral antagonism?) of certain tissues, the mechanism of which I could not find so anything I say in that regard will be useless lol.
What I take from that is that it is safe to use carnitine under a euthyroid condition as long as it is not in great excess, otherwise we would have all sorts of people going hypothyroid with the mass use of carnitine, and that in order to prevent hyperthyroid symptoms while taking T3 on a scale that will amplify fatloss, it is a good idea to supplement with carnitine.
Sorry if that was already apparent to everyone, I just gotta say it myself sometimes before it really sinks in.
So i guess i should lay off the LCLT while on t3 huh?? (only taking 1500mgED)
if on t4, no ALA. if using t4 and T3 you can use ALA just becareful when you come off as the synthriod effects will be reduced from ALA
Also i recommend a calcium supplement to keep thryroid in check.
agouti is shown to raise rT3 and show low or low normal levels of t3 and t4 while TSH is somewhat "normal"
posted this in the Lean Gains/ IF discussion log a couple minutes ago. for more studies on agouti and thyroid.