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J Trace Elem Med Biol. 2011 Jan;25(1):54-8. Epub 2010 Dec 3.
Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines.
Naghii MR, Mofid M, Asgari AR, Hedayati M, Daneshpour MS.
Source
Sport Physiology Research Center, Baqiyatallah (a.s.) University of Medical Sciences, Tehran, Islamic Republic of Iran. [email protected]
Abstract
Boron possesses widespread properties in biochemistry and nutrition. Acute supplementation with 11.6 mg of boron resulted in a significant increase in plasma boron concentration. Given such a fast bioavailability, the objective was to determine whether acute (hourly or daily), and weekly supplementation could have any significant biological effects on the steroid hormones and further on some inflammatory biomarkers. Eight healthy male volunteers attended the laboratory on three occasions (days 0, 1 and 7). On the first day (day 0), a blood sample collection at 8.00 A.M was followed by ingestion of placebo with the breakfast. On the next day (supplementation-day 1), similar procedure was followed by ingestion of a capsule containing 10mg of boron. On both occasions blood was collected every 2h for the next 6h. Subjects were requested to consume a capsule of 10mg boron every day with their breakfast, and on the day 7, the blood collection was carried out at 8.00 A.M, again. Boron in plasma increased significantly following hours and weekly consumption. Six hours supplementation showed a significant decrease on sex hormone binding globulin (SHBG), high sensitive CRP (hsCRP) and TNF-
