Bad Creatine? SwoleV2||San V12
- 07-02-2004, 01:37 AM
Bad Creatine? SwoleV2||San V12
Discovered a very well written article from:
Check it out, its some good info. Although im not going to say whats what, its something to take into consideration.
"Main part of the article regaurding this post"
No, this isn’t the tagline for a new type of creatine, it means that there’s a semi-popular creatine-like product on the market that may actually be harmful to your health. What’s worse is that there are now several copycat products on the market as well! As if that wasn’t bad enough, one of the potentially dangerous compounds (oh yes, there’s more than one!) that this product contains is ergolytic; i.e. something that decreases athletic performance.
This potentially dangerous ergolytic chemical is Guanidinopropionic Acid (GPA), which binds the creatine transporter and plugs it up so creatine can’t be transported into various tissues (similar to the concept of tamoxifen blocking the estrogen receptor, not allowing estrogen to bind). This is a problem, because most of our tissues can’t make creatine so it has to be transported in, and blocked transporters means a reduction in cellular creatine levels.
Bear in mind that creatine isn’t just a supplement, it’s a naturally occurring substance in our bodies that we need to survive! You know the impact of having 20% more creatine, now imagine having 80% less creatine! GPA induced creatine depletion can not only reduce muscle strength after a mere seven days of consumption (Gagnon et al., 2002), but has also been shown to convert fast-twitch muscle to slow-twitch (Ren et al., 1995)! So this substance might make you weaker and slower!
While these consequences should be enough to make you avoid supplements containing this chemical, there’s also a potentially dangerous side to consider: both our hearts and our brains have creatine transporters!!! Any time you start to mess around with our two most vital organs, it can’t be good. Fortunately, the brain seems to temporarily compensate for decreases in energy supply caused by GPA (O'Gorman et al., 1996), but do we really want our bodies to have to adapt to reduced energy levels? Of course not!
We also don’t want our hearts to be affected by GPA supplementation, but they are! In fact, 3 different studies showed that creatine levels in the heart dropped by 80-87% with GPA consumption in rats (Boehm et al., 2003, Neubauer et al., 1999; Horn et al., 2001). Now you can see why it’s nearly impossible to perform human studies using this substance! Clearly, you have to wonder what the manufacturers were thinking when they approved production of this supplement.
"But wait, there’s MORE! Order now and you’ll get another potentially dangerous ingredient for free!" One particular supplement ("SWOLE") combines GPA with another potentially dangerous substance known as Glycocyamine (G-amine). Sadly, G-amine (also known as guanidinoacetate) has been picked up by a few different supplement companies who obviously don’t do any research on what they’re getting people to ingest.
The reason G-amine is so popular (from a marketing standpoint, not from the consumers’) is because it is the precursor to creatine. Just like Testosterone can come from andro, creatine comes from G-amine. The theory is that you jack up G-amine levels and you get a whole bunch more creatine. The really asinine part is that, you can just directly take creatine!
We can’t take Testosterone due to legal reasons, so we have to find other ways to increase its levels—enter prohormones (among other effective things). But for our purposes, there’s no reason to worry about creatine precursors because we can just take the substance directly. The whole precursor concept is really hot when it comes to marketing to laymen, which is where this supplement takes off.
Unfortunately, consuming this chemical seems to have the undesirable effect of elevating blood levels of a substance called homocysteine, which is a very strong risk factor for cardiovascular disease (Stead et al., 2001). Cardiovascular disease is easily the number one killer in the Western World, and the last thing we need to do is increase our risk for it. Conversely, taking creatine decreases homocysteine levels, raising even more therapeutic possibilities for this supplement. As if to spit on your grave, if you’re supplementing with creatine, G-amine may also decrease its uptake by muscles (Zugno et al., 2003).
ALL INFO GIVEN TAKEN FROM THE LINK I POSTED ABOVE. T-MAG
- 07-02-2004, 01:59 AM
I remember PA stating his concerns over the new craze of volumizers back in the day. I always thought he was right to, and soome others also backed him that were chemists I think? I think I'm just gonna play it safe for now on and stick to either a custom made blend or some good 'ol EAS Phosphagen HP...does anybody know if they still make that stuff?
07-08-2004, 09:01 PM
07-08-2004, 10:23 PM
07-09-2004, 12:24 AM
I posted this a while back.
But I have an update, the info is true except for it being coincided with v12. V12 actually contains Betain-G-Amine which works well for non responders, without the negative sides. It also contains no GPA.
07-09-2004, 01:00 AM
07-09-2004, 01:38 AM
07-09-2004, 02:33 AM
Hmmm, I cant tell, I take so much ****, Bolt, Swole v2, body octane and OX.... I think it makes a little of a difference. BUt if its a good or bad difference I dont know. The problem is that bolt also contains GPA.
07-09-2004, 06:44 AM
I would say, just use one or the other since they both contain the same ingredient. Save one for a later time.Originally Posted by Grant
07-09-2004, 02:10 PM
Ya if uve got that much ull get the pump u want, u could also finish out the tub. I dont believe doing 1 tub will cause much dmg, but after that stick with reg creatine + ala or another decent one is Trac. Has reg creatine with no g-amine/GPA.
Also Sans V12 isnt bad.
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