CEE debunked yet again.

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    CEE debunked yet again.


    Biochem Biophys Res Commun. <javascript:AL_get(this, 'jour', 'Biochem Biophys Res Commun.');> 2009 Oct 16;388(2):252-5. Epub 2009 Aug 4.
    Non-enzymatic cyclization of creatine ethyl ester to creatinine.
    Giese MW.

    Department of Chemistry, Marian University, Indianapolis, IN 46222, USA. matthew.giese@comcast.net

    Abstract
    Creatine ethyl ester was incubated at 37 degrees C in both water and phosphate-buffered saline and the diagnostic methylene resonances in the (1)H NMR spectrum were used to identify the resultant products. It was found that mild aqueous conditions result in the cyclization of creatine ethyl ester to provide inactive creatinine as the exclusive product, and this transformation becomes nearly instantaneous as the pH approaches 7.4. This study demonstrates that mild non-enzymatic conditions are sufficient for the cyclization of creatine ethyl ester into creatinine, and together with previous results obtained under enzymatic conditions suggests that there are no physiological conditions that would result in the production of creatine. It is concluded that creatine ethyl ester is a pronutrient for creatinine rather than creatine under all physiological conditions encountered during transit through the various tissues, thus no ergogenic effect is to be expected from supplementation.


    I wonder how many studies will have to be presented before people realize the truth.
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    Quote Originally Posted by VaughnTrue View Post
    I wonder how many studies will have to be presented before people realize the truth.
    Ha, you lie. CEE is the best supplement in the whole wide world. It Revolutionized Creatine!

    /s
    Just inject.
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    Never will use any creatines other thanCreatine Nitrate.
    Best creatine ever used. I actually feel what creatine was invented to do. I use the APS version. Awesome results Look at the Creatine Nitrate. Will never use anything else
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    Quote Originally Posted by gatorguy220 View Post
    Never will use any creatines other thanCreatine Nitrate.
    Best creatine ever used. I actually feel what creatine was invented to do. I use the APS version. Awesome results Look at the Creatine Nitrate. Will never use anything else
    this

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