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megadosing L-carnitine

  1.  03-12-2011  10:56 AM
    Registered User phantom's Avatar
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    surprised no one has made a carnitine nitrate product yet



  2.  03-12-2011  08:38 PM
    Registered User nobel252's Avatar
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    So if you could only afford one which would it be for long term and more efficient for fat loss. 1.Acetyl-L-Carnitine Arginate Dihydrochloride
    2. Alcar
    3. Plcar
    4. Gplc

  3.  03-13-2011  09:24 AM
    Registered User Outstanding's Avatar
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    Originally Posted by phantom View Post
    surprised no one has made a carnitine nitrate product yet
    Nitrates are the new Ethyl Esters! Don't worry, if it's an ingredient, it will be created soon enough It looks better on the label, and if you make it, they will come.

  4.  03-13-2011  11:26 AM
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    Originally Posted by nobel252 View Post
    So if you could only afford one which would it be for long term and more efficient for fat loss. 1.Acetyl-L-Carnitine Arginate Dihydrochloride
    2. Alcar
    3. Plcar
    4. Gplc
    ALCAR FTW!!!!!!


    PLCAR and GPLC (GlycoCarn) is the same.

    GlycoCarn is a trademark brand of Sigma-tau HealthScience, Inc.



    Originally Posted by strategicmove View Post
    Essentially, all carnitine forms enhance the mitochondrial use of fatty acids. The advanced forms of L-Carnitine, namely, Acetyl-L-Carnitine, Propionyl-L-Carnitine, and Acetyl-L-Carnitine Arginate, are significantly more potent than simple L-Carnitine in terms of fat-loss and anti-aging benefits.

    Acetyl-L-Carnitine produces superior mitochondrial modulation of fatty acids. Dosage recommendation is between 1 000mg and 2 000mg per day.

    Propionyl-L-carnitine is a form of carnitine that has a special affinity for heart muscles, producing potent effects in cardiac and skeletal muscle, producing significant improvements in energy and stamina. Dosage recommendation is around 1 000mg daily.

    Combining the two should produce excellent results. If your budget does not permit this, you might prefer a combination of base L-Carnitine and ALCAR (PLCAR has its key benefit in the cardiovascular realm).

    As you know, ALA co-supplementation is a must, as Alpha Lipoic acid turns out to be a natural co-factor for a mitochondrial enzyme crucial in the break down of fatty acids. This enhances cellular energy efficiency. Furthermore, lipoic acid is a powerful antioxidant that enhances intracellular levels of vitamin C and glutathione, powerful antioxidants on their own.
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  5.  03-13-2011  11:40 AM
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    Originally Posted by MAxximal View Post
    ALCAR FTW!!!!!!


    PLCAR and GPLC (GlycoCarn) is the same.
    Propionyl-L-Carnitine is the same as Glycine-Propionyl-L-Carnitine?

    Doesn't the addition of the glycine dramatically change the effects of the product?

  6.  03-13-2011  06:04 PM
    Registered User MAxximal's Avatar
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    Originally Posted by Outstanding View Post
    Propionyl-L-Carnitine is the same as Glycine-Propionyl-L-Carnitine?

    Doesn't the addition of the glycine dramatically change the effects of the product?
    Glycine is a inhibitory amino acid.
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  7.  03-13-2011  06:25 PM
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    Originally Posted by Outstanding View Post
    Nitrates are the new Ethyl Esters! Don't worry, if it's an ingredient, it will be created soon enough It looks better on the label, and if you make it, they will come.
    The current nitrate patent (and product that everyone uses) is only covering amino acids at this point. It may be an issue with bonding something like carnitine to a nitrate. But I would be surprised if someone just used a 1:1 blend or something like that. The point of the "new" nitrate products is increased solubility when bonded with amino acids.
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  8.  03-14-2011  04:41 PM
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    Originally Posted by MAxximal View Post
    Glycine is a inhibitory amino acid.
    Can you explain this a little more please, and how it alters the relationship between GPLC and PLCAR?

    Originally Posted by Royd The Noyd View Post
    The current nitrate patent (and product that everyone uses) is only covering amino acids at this point. It may be an issue with bonding something like carnitine to a nitrate. But I would be surprised if someone just used a 1:1 blend or something like that. The point of the "new" nitrate products is increased solubility when bonded with amino acids.
    Well, I just purchase Creatine Nitrate, since it's now available in bulk powder form. I do like the amino acid Nitrates as well, and made another order to replenish my VPX Power Shock.

  9.  03-14-2011  07:29 PM
    Registered User MAxximal's Avatar
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    Originally Posted by Outstanding View Post
    Can you explain this a little more please, and how it alters the relationship between GPLC and PLCAR?



    Well, I just purchase Creatine Nitrate, since it's now available in bulk powder form. I do like the amino acid Nitrates as well, and made another order to replenish my VPX Power Shock.

    Propionyl-L-Carnitine (PLC) has been shown to best support healthy heart and skeletal muscle function. A patented and safe USP dietary form of PLC has been developed which is molecularly bonded to glycine, one of the precursor amino acids to carnitine biosynthesis.

    http://www.aminocarnitines.com/artic...rn_article.pdf
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  10.  03-15-2011  09:38 AM
    Banned Dr.Lang's Avatar
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    I take LCLT at 3 grams a day. That and 2 grams of ResV.

    I have to take them separately or the bowels will move, lol

  11.  03-15-2011  09:42 AM
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    I just heard from a friend that he stumbled across some research highlighting the fact Carnitine (not sure what form) can have some negative interaction with the Thyroid Gland function at higher dosages? Sorry my information is limited, but this has some pretty upsetting implications, although I'm not sure what constitutes 'mega' dosing, and as I said I'm not sure if this was LCLT, PLCAR, L-Carnitine base, etc.

    Oh well, just take Cytomel with it

  12.  03-15-2011  09:54 AM
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    Originally Posted by Outstanding View Post
    I just heard from a friend that he stumbled across some research highlighting the fact Carnitine (not sure what form) can have some negative interaction with the Thyroid Gland function at higher dosages? Sorry my information is limited, but this has some pretty upsetting implications, although I'm not sure what constitutes 'mega' dosing, and as I said I'm not sure if this was LCLT, PLCAR, L-Carnitine base, etc.

    Oh well, just take Cytomel with it
    maybe this can help us

    http://www.lef.org/magazine/mag2007/...thyroid_01.htm

    http://www.ncbi.nlm.nih.gov/pubmed/15591013
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  13.  02-07-2013  09:39 PM
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    Originally Posted by AntonG42O View Post
    some guy on here said that after megadosing L-carninite his sweat smelled like a dead fish. just throwing it out there
    I've been experimenting with dosing ALCAR and just yesterday I had this happen for what I think was the first time. My girlfriend said I stunk up the whole house. Dosing was 2g right after ~200mg of Na-RALA twice a day. Note: I recommend not mixing them together or the Na-RALA will stick to the cup, it's really nasty stuff consistency-wise, I may buy the pills next time for this bc the powder is really fine and hard to work with.

    Since then, I've decided to drop back down to 1g twice a day with the same amount of NA_RALA. One disclaimer: it was hard for me to tell if I had this, I couldn't smell it on myself so I had no clue until I came home from work and immediately my gf was appalled by my odor.

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