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megadosing L-carnitine

  1.  05-10-2010  07:44 PM
    NutraPlanet Fanatic dsade's Avatar
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    I have run it at over 20 grams a day. Watch out for your intestines as it can have a wicked laxative effect.

    Since this, and creatine, were the only products I could smuggle into AIT (right after basic), I dosed the liquid form 5 times a day with EXCELLENT body recomp results and amazing endurance.

    I'm looking to make a blended Liquid carnitine(fumerate, PLCAR, ALCAR, Tartarate) product here very soon.
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  2.  05-10-2010  07:49 PM
    Registered User EustisPanther's Avatar
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    Originally Posted by AntonG42O View Post
    some guy on here said that after megadosing L-carninite his sweat smelled like a dead fish. just throwing it out there
    This can definitely happen.

    I've dosed between 10-20g and my sweat smelled like old rotting fish in a dumpster. It's disgusting.

    But high doses proved to be very effective for me so besides the smell and potential for stomach discomfort I can't complain.

  3.  05-10-2010  07:50 PM
    Registered User thebigt's Avatar
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    Originally Posted by dsade View Post
    I have run it at over 20 grams a day. Watch out for your intestines as it can have a wicked laxative effect.

    Since this, and creatine, were the only products I could smuggle into AIT (right after basic), I dosed the liquid form 5 times a day with EXCELLENT body recomp results and amazing endurance.

    I'm looking to make a blended Liquid carnitine(fumerate, PLCAR, ALCAR, Tartarate) product here very soon.
    is there a reason for not including glpc, or is it purely a cost issue.

  4.  05-10-2010  07:54 PM
    NutraPlanet Fanatic dsade's Avatar
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    Originally Posted by thebigt View Post
    is there a reason for not including glpc, or is it purely a cost issue.
    I prefer PLCAR for sure, which is expensive enough. GPLC would add significant cost with very little to no (IMO) benefit.

    I will also be adding Pantethine and DL-Panthenol as a coenzyme A precursors with high efficiency and some evidence on its own supporting body recomposition.
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  5.  05-10-2010  08:04 PM
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    Originally Posted by dsade View Post
    I prefer PLCAR for sure, which is expensive enough. GPLC would add significant cost with very little to no (IMO) benefit.

    I will also be adding Pantethine and DL-Panthenol as a coenzyme A precursors with high efficiency and some evidence on its own supporting body recomposition.
    got to give you credit for sticking with plcar, with gplc getting so much praise these days. i know you have been a fan of plcar for a long time.

  6.  05-10-2010  08:04 PM
    Registered User kingdong's Avatar
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    Originally Posted by dsade View Post
    I prefer PLCAR for sure, which is expensive enough. GPLC would add significant cost with very little to no (IMO) benefit.

    I will also be adding Pantethine and DL-Panthenol as a coenzyme A precursors with high efficiency and some evidence on its own supporting body recomposition.
    I agree. I whant PLCAR, not GPLC. Your product sounds awsome. You should make an ALCAR free version to, because their is a small chunk of the population who do't enjoy the way they feel on it. I swear, it gives me a temper.

  7.  05-10-2010  09:25 PM
    Registered User Frequency's Avatar
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    Originally Posted by Outstanding View Post
    I was under the impression that LC in all forms exhibited some intrinsic anti oxidant activity in and of itself? Why the increased demand and necessity for supplemental AO's?
    Someone might clarify better or more accurately but carnitine brings fuel to your mitochondria. When this fuel is burned by your body oxidized waste material (free radicals) are formed. When your mega dosing carn your basically uping the potential for more free radicals. Its been a while since if read up on this stuff so if i missed or messed up on some finer points someone will correct me. A great solution some is green tea caps,a form of CoQ10, and maybe a form of r-ala if you can swing it.

  8.  05-10-2010  10:06 PM
    Registered User lonewolf0420's Avatar
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    Originally Posted by Frequency View Post
    Someone might clarify better or more accurately but carnitine brings fuel to your mitochondria. When this fuel is burned by your body oxidized waste material (free radicals) are formed. When your mega dosing carn your basically uping the potential for more free radicals. Its been a while since if read up on this stuff so if i missed or messed up on some finer points someone will correct me. A great solution some is green tea caps,a form of CoQ10, and maybe a form of r-ala if you can swing it.
    I can't rep you again

    I've been experimenting with ALA, to boost my AO's.


    In case I've miss read, what's considered "mega-dosing"?

  9.  05-10-2010  10:42 PM
    Registered User Frequency's Avatar
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    Originally Posted by lonewolf0420 View Post
    I can't rep you again

    I've been experimenting with ALA, to boost my AO's.


    In case I've miss read, what's considered "mega-dosing"?
    I dont recall seeing many supps going over 2 grams for a serving or daily dose so if i had to personally give it a number id probably say 6 grams or more daily. Dsade is more or less the supp king in this thread so i would like to see his opinion.
    I believe ALA also helps recycle certain AO's, like vitamin C, which just makes it all the better supp to take.

  10.  05-11-2010  06:11 AM
    Registered User MAxximal's Avatar
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    Originally Posted by dsade View Post
    I have run it at over 20 grams a day. Watch out for your intestines as it can have a wicked laxative effect.

    Since this, and creatine, were the only products I could smuggle into AIT (right after basic), I dosed the liquid form 5 times a day with EXCELLENT body recomp results and amazing endurance.

    I'm looking to make a blended Liquid carnitine(fumerate, PLCAR, ALCAR, Tartarate) product here very soon.

    Whoooot!!! i`m in and ready Matt

    Jeezzz this is GREAT NEWS
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    Got Glycophase ...?



  11.  05-11-2010  06:56 AM
    Registered User monstermash's Avatar
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    Originally Posted by dsade View Post
    I have run it at over 20 grams a day. Watch out for your intestines as it can have a wicked laxative effect.

    Since this, and creatine, were the only products I could smuggle into AIT (right after basic), I dosed the liquid form 5 times a day with EXCELLENT body recomp results and amazing endurance.

    I'm looking to make a blended Liquid carnitine(fumerate, PLCAR, ALCAR, Tartarate) product here very soon.
    Originally Posted by dsade View Post
    I prefer PLCAR for sure, which is expensive enough. GPLC would add significant cost with very little to no (IMO) benefit.

    I will also be adding Pantethine and DL-Panthenol as a coenzyme A precursors with high efficiency and some evidence on its own supporting body recomposition.
    Nice! Any idea to when this will be coming out?

  12.  05-11-2010  10:28 AM
    Registered User lonewolf0420's Avatar
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    I ran out of my ALCAR yesterday, and still waiting for my NP order to get here.

    I'm going through ALCAR withdrawal

  13.  05-11-2010  01:53 PM
    Registered User Outstanding's Avatar
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    Originally Posted by Frequency View Post
    Someone might clarify better or more accurately but carnitine brings fuel to your mitochondria. When this fuel is burned by your body oxidized waste material (free radicals) are formed. When your mega dosing carn your basically uping the potential for more free radicals. Its been a while since if read up on this stuff so if i missed or messed up on some finer points someone will correct me. A great solution some is green tea caps,a form of CoQ10, and maybe a form of r-ala if you can swing it.
    Excellent, great response. Thank you. I am on Glycobol with contains a very high amount of na-r-ALA, and I always take a greens supplement which contains an ORAC blend, so I believe I will be alright. I appreciate your help and explanation.

  14.  05-11-2010  02:05 PM
    Registered User rulk22's Avatar
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    Ive used all lots of L-carnitine before. LCLT, Acetyl, L-carnitine. Ive used up to 8grams a day but never thought to use 20-wow. Im a huge fan of L-carnitine and all its versions. The benefits ive seen are many, you can see and feel its effects for sure. Currently im running GPLC 3.5 grams, along with Arginocarn( imo currently the best form) 3 grams and im seeing great results. I get mine from Primordial Performance btw.

  15.  05-11-2010  02:22 PM
    Registered User lonewolf0420's Avatar
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    Does anyone know exactly how many mg are in a 1/4tsp of NP's bulk ALCAR? I'm guessing I consume about 2.8g with each serving I have. That's figuring about 700mg per 1/4tsp. I consume 2-3 servings a day.

    I can't believe how much I miss this stuff. I'm chomping at the bit, waiting for my order to arrive.

  16.  05-11-2010  02:24 PM
    Registered User kingdong's Avatar
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    Originally Posted by lonewolf0420 View Post
    Does anyone know exactly how many mg are in a 1/4tsp of NP's bulk ALCAR? I'm guessing I consume about 2.8g with each serving I have. That's figuring about 700mg per 1/4tsp. I consume 2-3 servings a day.

    I can't believe how much I miss this stuff. I'm chomping at the bit, waiting for my order to arrive.
    The old white bottle was 750mg.

  17.  05-11-2010  02:28 PM
    Registered User lonewolf0420's Avatar
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    Originally Posted by kingdong View Post
    The old white bottle was 750mg.
    Thank you. I would assume the black container would be the same.


    So the tiny "cc" scooper in the container would measure out 750mg?

  18.  05-13-2010  06:08 PM
    Registered User RAHHH's Avatar
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    Originally Posted by kingdong View Post
    Carnitine is one of those amino's that should do a lot, but it's L form has low bioavailability. Has anyone tried high dosed L-carnitine to see if it matches the effects of things like PLCAR and GPLC?

    why would you even bother.
    0.5g-1g of Acetyl L-Carnitine (ALCAR) would give you probibbly as much as 30g of just l-carnitine in terms of making it to your blood/brain ect.

    id just grab bulk ALCAR powder if i was you

  19.  05-13-2010  07:01 PM
    Registered User Frequency's Avatar
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    Originally Posted by RAHHH View Post
    why would you even bother.
    0.5g-1g of Acetyl L-Carnitine (ALCAR) would give you probibbly as much as 30g of just l-carnitine in terms of making it to your blood/brain ect.

    id just grab bulk ALCAR powder if i was you
    depends what you want it for exactly i suppose. Like i try to make clear i have very limited knowledge on most subjects i enter but ill share what i have... the acetylation of ALCAR is what gives carnitine its great ability to cross the blood brain barrier as opposed just mainly affecting mitochondria everywhere in the body. Depending on what is attached to carnitine, along with many other things, depicts what effect it will have. I believe propionyl-L-carnitine is the form that provides basic general carnitine benefits as the prpionyl(salt?ester?) helps with general absorption and plays some sort of role in the mitochondria.

  20.  05-13-2010  07:58 PM
    Registered User Outstanding's Avatar
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    There is an excellent article pertaining to LCLT and many of the subjects mentioned in this thread in this month's MD ironically (with Roelly Winklaar on the cover)

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