Two questions:
1. Would crushing up a 50mg DHEA tablet and taking it with Sustain Alpha liqua vade provide similar benefits to Dermacrine? As in would the sustain alpha help the DHEA be absorbed to the same level as dermacrine liqua vade?
2. I thought that one of (original) dermacrines benefits was that it reacted with the receptors on the skin of the back since thats where most of the steroid receptors were for DHEA. How does it work with the new liqua vade version then?
1) Our product contains more than just DHEA, though:
Supplement Facts
Serving Size: 5cc (5mL oral syringe)
Servings per container: 50
Amount Per Serving
%DV*
DHEA
34mg**
7,8-Benzoflavone (99%)
16mg**
Resveratrol (99%)
16mg**
Pregnenolone
8mg**
Chrysin (99%)
4mg**
*Daily Value
**Daily Value not established
Other Ingredients: Other ingredients: Liqua-Vade Technology [Distilled water, sorbitan monolaurate, exthoxylated sorbitan trioleate, ethoxylated mono and di-glycerides, medium chain triglycerides, sesame oil, grape spirits, phospholipid complex (phosphatidylcholine, lysophosphatidylcholine), glyceryl triacetate, glycerol monocaprylocaprate, hydroxyproply methylcellulose], malt syrup, trisodium citrate, natural vanilla flavor, sucralose, simethicone, potassium sorbate, sodium benzoate, citric acid, sucrose.
The formula itself was put together to maximize overall benefits, as well as mitigate some potential issues such as hair loss (secondary to 5a-reduction of testosterone (converted from DHEA) to DHT). The pregnenolone that's contained competes for that 5a-reductase enzyme; this helps to mitigate the potential for that conversion to occur.
This link explains the SEDDS (Self Emulsifying Drug Delivery System: AKA - Liqua-Vade) in more detail:
2) Those same steroidogenic enzymes (17b-HSD and 3b-HSD) are also contained in your liver, and serum blood. The conversions will still take place, but it may take just a bit longer. The huge benefit of the new Liqua-Vade delivery is that it's absorbing the compounds up to 3x more than our topical; this means a much greater potential for those conversion to take place due to quite a bit more compound available to convert to target hormones.
There are a high amount of these steroidogenic enzymes located in certain areas of the skin (where we suggest as appication sites), but you're only getting about 30% absorbtion with the topcial formula (you're getting up to 3x that with the Liqua-Vade delivery). In the end here, it's probably very similar in terms of results; maybe even better.