NSAIDs - bad for bodybuilding?

  1. New Member
    hl80's Avatar
    Stats
    5'10"  165 lbs.
    Join Date
    Jun 2009
    Posts
    60
    Rep Power
    98
    Level
    7
    Lv. Percent
    35.16%

    NSAIDs - bad for bodybuilding?


    I heard that taking NSAIDs (ibuprofin, naproxin, etc.) were bad for muscle development. Anybody know if there's any truth to this?

  2. New Member
    Chops89's Avatar
    Stats
    5'8"  170 lbs.
    Join Date
    Mar 2009
    Posts
    321
    Rep Power
    230
    Level
    14
    Lv. Percent
    74.52%

    They can apparently inhibit protein synthesis to an extent.
  3. New Member
    ecosocialist's Avatar
    Stats
    5'10"  174 lbs.
    Join Date
    May 2009
    Posts
    277
    Rep Power
    207
    Level
    13
    Lv. Percent
    96.05%

    Quote Originally Posted by Chops89 View Post
    They can apparently inhibit protein synthesis to an extent.
    Exactly. Talk to any of the arachidonic acid people, the more muscle inflammation you have, the more your body will bump up protein synthesis.
    •   
       

  4. Senior Member
    rubberring's Avatar
    Stats
    5'10"  200 lbs.
    Join Date
    Dec 2007
    Age
    41
    Posts
    2,933
    Rep Power
    5424
    Level
    38
    Lv. Percent
    46.29%
    Achievements Activity ProPosting Pro

    Strangely enough, there was a study out not too long ago that had the opposite results. Granted, the subjects were older men, but protein synthesis obviously wasn't an issue.

    http://www.sciencedaily.com/releases...0406153404.htm

    "Taking daily recommended dosages of ibuprofen and acetaminophen caused a substantially greater increase over placebo in the amount of quadriceps muscle mass and muscle strength gained during three months of regular weight lifting, in a study by physiologists at the Human Performance Laboratory, Ball State University."

    Either way, the negative effects on the liver in long-term use would cancel out any positive anabolic response.
    RTR.
  5. New Member
    Chops89's Avatar
    Stats
    5'8"  170 lbs.
    Join Date
    Mar 2009
    Posts
    321
    Rep Power
    230
    Level
    14
    Lv. Percent
    74.52%

    Quote Originally Posted by rubberring View Post
    Strangely enough, there was a study out not too long ago that had the opposite results. Granted, the subjects were older men, but protein synthesis obviously wasn't an issue.

    http://www.sciencedaily.com/releases...0406153404.htm

    "Taking daily recommended dosages of ibuprofen and acetaminophen caused a substantially greater increase over placebo in the amount of quadriceps muscle mass and muscle strength gained during three months of regular weight lifting, in a study by physiologists at the Human Performance Laboratory, Ball State University."

    Either way, the negative effects on the liver in long-term use would cancel out any positive anabolic response.
    Interesting. Regardless, I would say popping a few Advil/Aleve/Aspirin, etc. here and there isn't really going to make any difference.
  6. New Member
    AABigRick's Avatar
    Join Date
    Apr 2007
    Posts
    285
    Rep Power
    236
    Level
    14
    Lv. Percent
    1.11%

    So now we have studies saying that it inhibts protein synthesis, and other other studies saying that it does not. The world will never know. lol. I never had a problem when I was on motrin for a month at 2400mg a day. Just remember everyone responds differently.
  

  
 

Similar Forum Threads

  1. Study on NSAIDs and Test/Epitest Glucuronidation
    By dumbhick3 in forum Anabolics
    Replies: 5
    Last Post: 01-28-2010, 11:58 PM
  2. Knee Pain NSAIDS
    By MuscleBound1337 in forum OTC Drug
    Replies: 2
    Last Post: 03-31-2008, 02:27 PM
  3. Herbal alternatives to NSAIDs
    By gogo in forum Supplements
    Replies: 6
    Last Post: 02-28-2007, 05:12 PM
  4. NSAIDS delay prostate enlargement
    By yeahright in forum OTC Drug
    Replies: 3
    Last Post: 08-31-2006, 03:19 PM
  5. Bodybuilding is not what it used to be
    By MaDmaN in forum General Chat
    Replies: 25
    Last Post: 02-15-2006, 09:31 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
Log in
Log in