Tamoxifene and Formestane synergy - AnabolicMinds.com

Tamoxifene and Formestane synergy

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    Tamoxifene and Formestane synergy



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    Good post
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    good for breast cancer but would def turn off to much estrogen in sum1 juss concerned with estrogen control and would def not only dry out ur joints but destroy ur libido..juss my hypothesis though havent actually tested it
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    Quote Originally Posted by bigdave View Post
    good for breast cancer but would def turn off to much estrogen in sum1 juss concerned with estrogen control and would def not only dry out ur joints but destroy ur libido..juss my hypothesis though havent actually tested it
    are you referring to tamox, form, or the combination?
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    Quote Originally Posted by bigdave View Post
    good for breast cancer but would def turn off to much estrogen in sum1 juss concerned with estrogen control and would def not only dry out ur joints but destroy ur libido..juss my hypothesis though havent actually tested it
    How do you figure that. Tamoxifen is a serm, it doesnt lower estrogen (afaik) but binds to estrogen receptors. Formestane is an AI, that does lower estrogen. Taking too much formestane will probably lower libido but that doesnt have anything to do with the tamoxifen or its interaction with tamoxifen.
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    exactly a serm binds onto some estrogen receptors not allowing estrogen to show its full effect while AI's block estrogen period. so unless you were on a whole lotta juice that was converting to estrogen i dont believe theres a practical application of running both
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    lol ppl SERM are test boosters, ok let me explain alil
    Tamoxifen binds to a estro receptor cant remember if its the alpha or beta in a depleated state, ther for no estroginic effect can take place, but the also boost test threw LH secreation. i read a study awhile ago about a man that was on clomid and amridex(sp) and he got his test up to 10.000, because using a SERM in low dose perticualry with an AI can shoot yer test threw the roof. its like turing on the faucet but almost closing the drain

    Quote Originally Posted by bigdave View Post
    exactly a serm binds onto some estrogen receptors not allowing estrogen to show its full effect while AI's block estrogen period. so unless you were on a whole lotta juice that was converting to estrogen i dont believe theres a practical application of running both


    AIs dont block estrogen at all, they only enhibit the amromatase eynsyme(sp)

    the study is saying that Formestane alows Tamoxifen to be active longer which is a good thing u would need less of a dose, or it allows more Tamoxifen to pass therw the liver without being Metabolised
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    Quote Originally Posted by bigdave View Post
    exactly a serm binds onto some estrogen receptors not allowing estrogen to show its full effect while AI's block estrogen period. so unless you were on a whole lotta juice that was converting to estrogen i dont believe theres a practical application of running both
    Well the combination seems more effective then either standalone when battling gyno.
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