Yup yup, I had to start with 1 for tolerance, and even at 1 I was wide awake but when I got my 3 hours sleep, felt AMAZING. This supp does wonders in aiding the bodies recovery.
We gathered some pretty sexy data on that fact with HEALTHY adults and THIRD PARTY RESEACH (Meaning they have no financial interest in producing a positive study):
The 221% value was the mean figure taken from the plasma GH increases in a younger group of 44 individuals (31-44) and older group of 42 individuals (64-88). Study was performed with 500mg l-DOPA without decarboxylase inhibitor adjuvant administration. Two capsules of PowerFULL, containing a standardized extract of Mucuna Pruriens, contains the equivalent to 500mg synthetic l-DOPA. Individuals had healthy GH metabolism.
In terms of definite amount of IUs, I familiar with two values in the marketing: a figure of 3IU and a figure of 12IU. As per the 3IU figure, if you take the average baseline plasma GH figures given in the Greenspan study, and apply the 221% using the same reference range, the result is an average increase of approximately 1mg. All compounds have a different IU equivalent, and GH’s is 1mg = 3IU. This could be a plausible source for the 3IU figure. However, you have to note that 1mg GH is the equivalent amount to 3IU, which is not the same as saying, “It is like injecting 3IU of synthetic growth hormone”. Exogenous GH is susceptible to metabolism once in the body, so injecting 3IU GH will most likely not produce a plasma GH increase of 1mg; that is merely the amount of GH contained in 3IU.
As per the 12IU figure, this most likely stems from an equivocation of the Greenspan study, which noted substantially higher mean plasma GH increases than the Lin and Tucci studies. The studies are included below for reference.
Dopaminergic regulation of gonadotropin and thyrotropin hormone secretion is altered with age. Greenspan SL, Sparrow D. Horm Res. 1991;36(1-2):41-6.
Provocative tests of growth-hormone release. A comparison of results with seven stimuli. Lin T, Tucci JR. Ann Intern Med. 1974 Apr;80(4):464-9