Predaking
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Do large doses of glutamine have any positive/negative nootropic effects?
I dunno. I would think that, like anything else, if your body doesn't need it, it excretes it through urine.What if you took 50g?
What he said! lolGlutamine is only going to produce a noticeable nootropic if your are deficient in glutamate. Since Glutamate is the most abundant excitatory neurotransmitter in humans, it is doubtful that you are going to be deficient. If your looking for a nootropic boost from the glutamine family, check out pyroglutamic acid. It helps increase oxygen in the brain and preserves the brains stores of ACh.
I made a post about this not to long ago, not sure what forum topic it was under. I havnt watched the vid yet but what i had posted was in reference to glutamine. Dr. Colgan of the Colgan Institute (google them) has found out that if you use glutamine, you are whacking your body with ammonia. Dry glutamine powder degrades into ammonia and pyroglutamic acid, wehther absorbed into a liquid solution and even in your stomach. Thats it in a nutshell. Instead, use ornithine and alpha-ketoglutarate. Both are ammonia scavengers and will produce a readily supply of glutamine within the body.idk but there are some people on youtube claiming it is toxic. like this http://www.youtube.com/watch?v=ExyNf3u7iQg
i think this guy doesn't what he is talking about. i hope someone has more to add on this topic since we consume mass amounts of glatamic acid via protein shakes.
So to sum it up, use ornithine and alpha-ketoglutarate. Could you elaborate as far as dosages and the exact differences between the two. I mean should they only be used together, are they worth doubling up? Is taking one just fine? I realize thats a lot of questions but you seem you know your buisness.I made a post about this not to long ago, not sure what forum topic it was under. I havnt watched the vid yet but what i had posted was in reference to glutamine. Dr. Colgan of the Colgan Institute (google them) has found out that if you use glutamine, you are whacking your body with ammonia. Dry glutamine powder degrades into ammonia and pyroglutamic acid, wehther absorbed into a liquid solution and even in your stomach. Thats it in a nutshell. Instead, use ornithine and alpha-ketoglutarate. Both are ammonia scavengers and will produce a readily supply of glutamine within the body.
Im sure there may be opposing articles out there yet the Colgan Institute has been testing athletes for many years along with all forms of nutrition and supplements.
The info I gave you was from a nutrition book that I have, I only know what I read..lol. Let me take a gander and report back. Ok..it states that for maximum anabolism, each meal should include 2-4 grams of ornithine alpha-ketoglutarate. In addition, each post exercise meal should include 2-4 grams of ketoisocaproate.So to sum it up, use ornithine and alpha-ketoglutarate. Could you elaborate as far as dosages and the exact differences between the two. I mean should they only be used together, are they worth doubling up? Is taking one just fine? I realize thats a lot of questions but you seem you know your buisness.
Why do you still take it if you dont "feel" any different on or off? Seems like a waste of money to me. Especially when you can get Glutamine in ON whey protein and Xtend.Like I mentioned in another post: I don't 'feel' any difference on it or off it. I still take it since its been a staple of mine for years. I ingest 10g/day.
I dont buy the neuro-toxicity complaint, in fact, that guy needs to drink some muscle milk and put some mass on those bones.
It can't be more toxic than people who ingest pills everyday, or drink high levels of alchohol; I'd be more concerned about the latter than L-Glutamine.
wikipedia gave me the following when i instinctively typed in "ach brain" into google lol:Glutamine is only going to produce a noticeable nootropic if your are deficient in glutamate. Since Glutamate is the most abundant excitatory neurotransmitter in humans, it is doubtful that you are going to be deficient. If your looking for a nootropic boost from the glutamine family, check out pyroglutamic acid. It helps increase oxygen in the brain and preserves the brains stores of ACh.
You can supplement with choline, but your body limits the amount of Ach by preventing uptaking of the choline into your nerves. Its only going to make a difference if your deficient or possibly if you are in a situation where you need higher amounts of choline to synthesize into Ach. Ach is made from dietary choline intake and B-5 (I believe) so its not like its some crazy chemical that you can only get by injecting it in you @ss lol. How does it sound risky to you? I should also mention that once Ach binds with protein receptor at the muscular nerve it is broken down by acetylcholinesterase AchE, so the only thing that would be risky IMO is taking a AchE inhibitor (which I don't think anyone is going to do) If you ever want to see the effects of an AchE inhibitor, spray DDT bug spray on an insect. You will notice the bug tenses up completely and then dies, thanks to all that Ach not being broken down.can it be supplemented?
if it can be, it sounds risky at best