TTA PPAR Antagonist??

  1. New Member
    shanebee's Avatar
    Join Date
    Aug 2008
    Posts
    19
    Rep Power
    87
    Level
    4
    Lv. Percent
    22.62%

    TTA PPAR Antagonist??


    All the write ups I've read say that TTA is a PPAR Antagonist, that doesn't make since at all, especially when it says PPAR Alpha (the co-factor PGC-1Alpha i assume?), that transcription factor is a gene promoter for mitochondria function, it doesn't make since to antagonize the PPAR receptor and increase metabolism. Hopefully the write up was wrong and they meant agonist, or maybe i totally don't understand that pathway, but in the research we do at school, we have been looking at PGC1Alpha and it's effects on mitochondria function, so I do know a thing or two about this stuff .


    i checked pubmed.. i found a handful of articles stating its a PPAR agonist not antagonist >< that scares me.. who wrote that writeup and how could you knowing write the other stuff without knowing what a agonist/antagonist is? typo i hope.

  2. Board Sponsor
    sns8778's Avatar
    Join Date
    Jul 2005
    Posts
    737
    Rep Power
    7763
    Level
    21
    Lv. Percent
    67.48%

    Quote Originally Posted by shanebee View Post
    All the write ups I've read say that TTA is a PPAR Antagonist, that doesn't make since at all, especially when it says PPAR Alpha (the co-factor PGC-1Alpha i assume?), that transcription factor is a gene promoter for mitochondria function, it doesn't make since to antagonize the PPAR receptor and increase metabolism. Hopefully the write up was wrong and they meant agonist, or maybe i totally don't understand that pathway, but in the research we do at school, we have been looking at PGC1Alpha and it's effects on mitochondria function, so I do know a thing or two about this stuff .


    i checked pubmed.. i found a handful of articles stating its a PPAR agonist not antagonist >< that scares me.. who wrote that writeup and how could you knowing write the other stuff without knowing what a agonist/antagonist is? typo i hope.
    Was a typo and was corrected, but some retailer sites never updated it when the revised write up was sent out. Sorry for any confusion as most people familiar with TTA knew it was typo, so had never been a big deal. Hope that clarifies.
    Focus XT - Mental Clarity, Focus, & Concentration

    Piracetam Capsules & Powder Available at Nutraplanet
    Limited Time* One Run Only Item
  3. New Member
    shanebee's Avatar
    Join Date
    Aug 2008
    Posts
    19
    Rep Power
    87
    Level
    4
    Lv. Percent
    22.62%

    seems like its still a typo on nutraplanet
    •   
       

Similar Forum Threads

  1. Prolactin Antagonist..
    By Tyler3295 in forum Anabolics
    Replies: 11
    Last Post: 06-07-2011, 11:12 PM
  2. PPAR Delta/Alpha Agonists- TTA and ??
    By missmolly in forum Supplements
    Replies: 6
    Last Post: 06-12-2009, 03:09 AM
  3. What are some PPAR Delta/Alpha Agonists?? TTA is one -- and??
    By missmolly in forum Male Anti-Aging Medicine
    Replies: 0
    Last Post: 06-10-2009, 12:05 AM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
Log in