JohnnieFreeze
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If I read this right it looks like Rhodiola has a profound effect on Testosterone among other things..(I pasted the short version..you can read the whole write up here- Rhodiola and used thereof - Patent 6399116 )
Abstract:
The present invention relates to Rhodiola, preferably Rhodiola crenulata, to treat various conditions and diseases in mammals. Rhodiola crenulata is a Tibetan herb which has been discovered to have highly useful and beneficial properties heretofore unknown. Rhodiola crenulata is especially preferred to enhance blood oxygen levels, to enhance working capacity and endurance, to enhance memory and concentration, to enhance cardiac and cardiovascular function, to provide antioxidant effects, to protect against oxidation, to modulate testosterone and estradiol levels, to modulate sleep, and to enhance sexuability, such as improve sexual performance.
Claims:
What is claimed:
1. A method of enhancing transport of blood oxygen in a subject having muscle fatigue, comprising, administering an effective amount of a water and/or alcoholic extract obtained from the roots or rhizome of Rhodiola crenulata to said subject, wherein said extract contains 2-10%, by weight, of salidroside, whereby said amount of Rhodiola is effective to reduce blood levels of lactic acid.
2. A method of claim 1, wherein said amount of Rhodiola is further effective to raise skeletal muscle levels of ATP.
3. A method of claim 2, wherein the skeletal muscle levels of ATP are raised at least 30%.
4. Am method of claim 1, wherein blood levels of lactate are reduced at least 20%.
5. A method of claim 1, with the proviso that said subjects do not have lung inflammation, coughing, or an external wound or burn.
In preferred embodiments, the present invention relates to a method of increasing testosterone levels in a host in need thereof, comprising, administering an effective amount of a Rhodiola to said host. Testosterone, principal male hormone, or androgen, is produced mainly in the Leydig cells in the male testes. The Leydig cells also produce two other androgens of less potency and in much smaller quantities. Testosterone stimulates the development of the male secondary sex characteristics after puberty, causing growth of the beard and pubic hair, development of the penis, and change of voice. The hormone also aids in growth, muscular development, and masculine body contour of the adult male.
Testosterone is considered to be a male virilizing hormone. Its effects include maintenance of muscle and bone mass, improving and/or enhancing sexual function and psychological well being among others. As males grow older, especially after the age of 35, a slow decline in testosterone levels is observed which is accompanied by symptoms that have been associated with the condition known as “andropause”. Symptoms of andropause include lethargy, depression, lack of sexual desire and function, and loss of muscle mass and strength. Increasing testosterone levels therefore can be useful to treat any of the mentioned conditions. Additionally, increasing testosterone levels can be useful in treating certain types of breast cancer in women.
Testosterone levels refer to the amounts of testosterone which are circulating in the blood, e.g., as measured using enzyme-linked immunosorbent assay, HPLC, or any other suitable detection method.
Any effective amount of Rhodiola crenulata can be administered. In accordance with present invention, it has been demonstrated that intake of a standardized Rhodiola crenulata extract (e.g., having 0.1-10%. Preferably 1-6%) salidroside by total weight of composition) produced a significant increase in total testosterone as compared to placebo. For example, after taking 2 grams of standardized rhodiola extract with 2% salidroside, once a day for a month, subjects showed about a 76% increase in total testosterone in the blood as compared to the 6.0% increase in total testosterone level after taking placebo for a month. These amounts, however, can be increased by any value, e.g., at least about 5%, 10%, 15%, 20%, 50%, 60% 70%, 75%, 100%, 2-fold, 5-fold, etc., over amounts which are present in the blood prior to administration.
The present invention also relates to a method of increasing estradiol levels in a host in need thereof, comprising, administering an effective amount of a Rhodiola to said host.
Abstract:
The present invention relates to Rhodiola, preferably Rhodiola crenulata, to treat various conditions and diseases in mammals. Rhodiola crenulata is a Tibetan herb which has been discovered to have highly useful and beneficial properties heretofore unknown. Rhodiola crenulata is especially preferred to enhance blood oxygen levels, to enhance working capacity and endurance, to enhance memory and concentration, to enhance cardiac and cardiovascular function, to provide antioxidant effects, to protect against oxidation, to modulate testosterone and estradiol levels, to modulate sleep, and to enhance sexuability, such as improve sexual performance.
Claims:
What is claimed:
1. A method of enhancing transport of blood oxygen in a subject having muscle fatigue, comprising, administering an effective amount of a water and/or alcoholic extract obtained from the roots or rhizome of Rhodiola crenulata to said subject, wherein said extract contains 2-10%, by weight, of salidroside, whereby said amount of Rhodiola is effective to reduce blood levels of lactic acid.
2. A method of claim 1, wherein said amount of Rhodiola is further effective to raise skeletal muscle levels of ATP.
3. A method of claim 2, wherein the skeletal muscle levels of ATP are raised at least 30%.
4. Am method of claim 1, wherein blood levels of lactate are reduced at least 20%.
5. A method of claim 1, with the proviso that said subjects do not have lung inflammation, coughing, or an external wound or burn.
In preferred embodiments, the present invention relates to a method of increasing testosterone levels in a host in need thereof, comprising, administering an effective amount of a Rhodiola to said host. Testosterone, principal male hormone, or androgen, is produced mainly in the Leydig cells in the male testes. The Leydig cells also produce two other androgens of less potency and in much smaller quantities. Testosterone stimulates the development of the male secondary sex characteristics after puberty, causing growth of the beard and pubic hair, development of the penis, and change of voice. The hormone also aids in growth, muscular development, and masculine body contour of the adult male.
Testosterone is considered to be a male virilizing hormone. Its effects include maintenance of muscle and bone mass, improving and/or enhancing sexual function and psychological well being among others. As males grow older, especially after the age of 35, a slow decline in testosterone levels is observed which is accompanied by symptoms that have been associated with the condition known as “andropause”. Symptoms of andropause include lethargy, depression, lack of sexual desire and function, and loss of muscle mass and strength. Increasing testosterone levels therefore can be useful to treat any of the mentioned conditions. Additionally, increasing testosterone levels can be useful in treating certain types of breast cancer in women.
Testosterone levels refer to the amounts of testosterone which are circulating in the blood, e.g., as measured using enzyme-linked immunosorbent assay, HPLC, or any other suitable detection method.
Any effective amount of Rhodiola crenulata can be administered. In accordance with present invention, it has been demonstrated that intake of a standardized Rhodiola crenulata extract (e.g., having 0.1-10%. Preferably 1-6%) salidroside by total weight of composition) produced a significant increase in total testosterone as compared to placebo. For example, after taking 2 grams of standardized rhodiola extract with 2% salidroside, once a day for a month, subjects showed about a 76% increase in total testosterone in the blood as compared to the 6.0% increase in total testosterone level after taking placebo for a month. These amounts, however, can be increased by any value, e.g., at least about 5%, 10%, 15%, 20%, 50%, 60% 70%, 75%, 100%, 2-fold, 5-fold, etc., over amounts which are present in the blood prior to administration.
The present invention also relates to a method of increasing estradiol levels in a host in need thereof, comprising, administering an effective amount of a Rhodiola to said host.
