this question is one which does not have a definite answer man. Unless someone goes out, takes samples of each protein manufacturer and test its efficiency, no one can tell you whats best. If you're asking for each individual's preference as far as taste, cost, accessibility, and/or mixability...then thats something else. Ive tried optimum, eas simiply, sportsone whey2, vp2 isolate, isopure, and maybe some others as for straight whey. For blends, ive had metrx protein plus, hdt problend55, and labrada's prov60. I choose simply and metrx protein plus for the two categories. (both in chocolate) now, this is putting cost and taste together. but hey, the old saying goes (which is pretty close to the truth)....whey is whey. (ha)