- 11-15-2008, 12:48 PM
- 11-15-2008, 12:57 PM
It will raise your test levels. That means an increase in libido, but I don't think it'll build muscle.
11-15-2008, 01:04 PM
11-15-2008, 01:26 PM
"Anabolic steroids (of which testosterone is one) have also been taken to enhance muscle development, strength, or endurance. They do so directly by increasing the muscles' protein synthesis."
"As testosterone is one of the body's major growth hormones, on average men find hypertrophy much easier to achieve than women."
11-15-2008, 03:25 PM
11-15-2008, 05:36 PM
11-15-2008, 05:51 PM
further, it is believed that the lost resveratrol that is metabolized into conjugated form of glucuronate it can still provide it's purported health benefits.
in certain instances, glucuronidation works to deliver a particular active ingredient to cells.
it seems that resveratrol is delivered to cells, at least in part, in glucuronidated form.
Nature Reviews Drug Discovery 5, 493-506 (June 2006) | doi:10.1038/nrd2060
Therapeutic potential of resveratrol: the in vivo evidence
Joseph A. Baur1 and David A. Sinclair1 About the authors
Resveratrol, a constituent of red wine, has long been suspected to have cardioprotective effects. Interest in this compound has been renewed in recent years, first from its identification as a chemopreventive agent for skin cancer, and subsequently from reports that it activates sirtuin deacetylases and extends the lifespans of lower organisms. Despite scepticism concerning its bioavailability, a growing body of in vivo evidence indicates that resveratrol has protective effects in rodent models of stress and disease. Here, we provide a comprehensive and critical review of the in vivo data on resveratrol, and consider its potential as a therapeutic for humans.
11-15-2008, 07:48 PM
11-15-2008, 08:04 PM
Quercetin enhances resveratrol's bioavailability.
Quercetin inhibits human P-form sulphotransferases, and induces glutathione S-transferase . Inhibition of resveratrol sulphation in both the liver and duodenum have been confirmed . Additionally, quercetin displays non-competitive inhibiton of acetaminophen, minoxidil, and p-nitrophenol sulfation [1,3].
 Walle et al. Quercetin, a potent and specific inhibitor of the human P-form phenolsulfotransferase. Biochem. Pharmacol. 50, 731-735 (1995).
 De Santi et al. Sulphation of resveratrol, a natural product present in grapes and wine, in the human liver and duodenum. Xenobiotica 30, 609?617 (2000).
 Eaton et al. Flavonoids, potent inhibitors of the human P-form phenolsulfotransferase. Potential role in drug metabolism and chemoprevention American Society for Pharmacology and Experimental Therapeutics Volume 24, Issue 2, pp. 232-237, 02/01/1996 (1996)
Bioprene has been shown to enhance the serum concentration/bioavailability of polyphenols, by significantly blunting the extensive intestinal and/or hepatic glucuronidation and sulfation. The lecethin should speed-up the entire process via enhanced dissolution kinetics and transit times.
"Concomitant administration of piperine 20 mg produced much higher concentrations from 0.25 to 1 h post drug (P < 0.01 at 0.25 and 0.5 h; P < 0.001 at 1 h), the increase in bioavailability was 2000%."
"The study shows that in the dosages used, piperine enhances the serum concentration, extent of absorption and bioavailability of curcumin in both rats and humans with no adverse effects."
Planta Med. 1998 May;64(4):353-6.
Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers.
Influence of piperine on the pharmacokinetics of c...[Planta Med. 1998] - PubMed Result
11-15-2008, 08:19 PM
11-16-2008, 12:58 PM
11-16-2008, 07:39 PM
11-16-2008, 07:50 PM
11-16-2008, 07:59 PM
11-16-2008, 08:24 PM
Great timing!! I am on my last few drops of Dermacrine and ready for Sustain-ance.
Always open light. Itís not what you open with, itís what you finish with. Louie Simmons
11-17-2008, 10:45 AM
sustain alpha doesnt seem to be working liked i hoped for me..maybe its the weather.. libido isnt up nor the loads havent improved either
11-17-2008, 12:27 PM
11-17-2008, 09:57 PM
11-18-2008, 01:38 AM
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