Also on your question for where to apply the product, the upper back and shoulders are the best areas. The reason being is how the product functions. The skin in those areas has the highest concentration of enzymes to convert the product to 1-AD and then to 1-Test. Although some logic would point to muscle group specific application but that is not how it works. It is absorbed by the skin and then converted and enters the blood stream and is circulated to the entire body. You could apply it anywhere on the skin and it will enter the blood stream and circulate. The theory of localization does not apply to these types of products.