- 09-10-2008, 01:56 AM
I'm not trying to scare anyone away from the supplement, apparently, from what I've read, it's top notch AI. As well, Ergophram is a reputable company and my intentions are not to slander the company in any way.
The reason I'm posting this is because I'm considering using 6-oxo, (I already had 2 bottles purchased), and among my intensive internet browsing and research I came across and Canadian Health Advisory stating a serious health issue, quoting the first paragraph of the article;
"Health Canada is warning consumers not to use the dietary supplements 6-OXO (4-androstene-3,6,17-trione) and 1-AD (1-androstenediol), or any other supplements containing the ingredients 4-androstene-3,6,17-trione or 1-androstenediol, due to potentially serious health risks such as seizures and blood clots in the brain that can lead to disability."
Being a fairly recent article, it may not be common knowledge for most and I encourage everyone to take a quick read through. If anyone would like to contribute to this information with personal trial, please do so. As for the website itself, search google "Canada 6 oxo" and it should be the first site amongst the list.
- 09-10-2008, 01:58 AM
I've heard of them though my what I'm about to say is not really helpful.
I cannot remember where the hell I heard of them.. for some reason Phishing comes to mind but don't quote me on that completely though.
09-10-2008, 11:37 AM
09-10-2008, 11:44 AM
They have to try to justify the reasons for their draconian supplement laws some way.
Now ask them why Carnitine is illegal.
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09-10-2008, 11:56 AM
Oh geez, if 6-OXO was going to kill you I woulda died five years ago. I'm more concerned about the teflon on my no stick pans, the plasticizers in my plastic water bottles, cell phone radiation, the ozone layer, the world oil crisis and spontaneous human....in that order.
09-10-2008, 01:33 PM
09-10-2008, 01:52 PM
09-10-2008, 07:15 PM
Geez! Do they have any evidence to support this. I'm betting there was one case of some complications with one individual who was coincidentaly taking 6 oxo while inknowingly havin a serious pre existing condition so they claim there is a cause and effect senario between the two! This is so academically lazy i'm actually going to spew!
You know what causes bloodclots in the brain SMOKING!!!!!!
Funny how when your making 70% tax on a product no justifiable prohibition occurs in the face of insummountable evidence demonstrating a cause and effect senario.
09-10-2008, 07:22 PM
09-10-2008, 07:33 PM
09-10-2008, 10:08 PM
09-10-2008, 10:12 PM
Well, considering it's a country wide advisory, there is definite cause for concern I would say, but I agree, the fact the there is only one case in which one individual developed seizures and blood clots in his brain without any facts or documentation supporting the case, there are too many unknown variables to just write the product off. You never know, maybe the dude was choking down half of bottle a day or something.
Anyway, I'm more than likely going through with the recommend dosage at 3 - 6 pills /day, this won't be for a few months yet, but I like to order my supps well in advance and research the products fully, which is what this site is all about, no?
Thanks for the posts btw.
09-10-2008, 10:33 PM
09-10-2008, 10:34 PM
09-10-2008, 10:51 PM
Whole blood clinical safety markers
Table 2 shows the measured mean ± SD values for the
whole blood clinical chemistry markers. The results demonstrated no significant group × time interaction (p =
0.829) or main effects for test (p = 0.567), indicating that
there were no significant differences in whole blood clinical
safety markers over the course of the study. However,
the results did show a significant main effect for group,
indicating that the 600 mg group had higher baselines values
for hematocrit (p = 0.030), absolute monocytes (p =
0.027), and absolute basophils (p = 0.018) that persisted
throughout the study, and was apparently independent of
Serum clinical safety markers
Table 3 shows the measured mean ± SD values for the
serum clinical chemistry markers. Results showed no significant
group × time interaction (p = 0.815) or main
effects for test (p = 0.671) indicating that there were no
significant differences in whole blood clinical safety markers
over the course of the study. However, the results did
show significant main effects for group and revealed that
the 600 mg group was shown to have significantly higher
baseline values for total cholesterol (p = 0.02), low density
lipoprotein (p = 0.01), blood urea nitrogen (p =
0.016), GGT, calcium, total blood protein, and albumin
(p = 0.01) that persisted throughout the study, and was
apparently independent of 6-OXO supplementation.
Urine clinical safety markers
Table 4 shows the measured mean ± SD values for the
urine clinical chemistry markers. The results revealed no
significant group × time interaction (p = 0.794) or main
effect for test (p = 0.543) or time (p = 0.693) indicating
that there were no significant differences in urine clinical
safety markers over the course of the study.
Hemodynamic clinical safety markers
Table 5 shows the measured mean ± SD values for the
hemodynamic clinical safety markers. There was no significant
group × time interaction (p = 0.725) or main effect
for test (p = 0.583) demonstrating no significant differences
in hemodynamic measures over the course of the
study. However, the results did show a significant main
effect for group and revealed that the 300 mg group had a
significantly higher baseline SBP (p = 0.041) that persisted
throughout the study, and was apparently independent
of 6-OXO supplementation.
Effects of eight weeks of an alleged aromatase inhibiting nutritional supplement 6-OXO (androst-4-ene-3,6,17-trione) on serum hormone profiles and clinical safety markers in resistance-trained, eugonadal males
Dan Rohle1, Colin Wilborn2, Lem Taylor3, Chris Mulligan4, Richard Kreider5
and Darryn Willoughby
Published: 19 October 2007
Journal of the International Society of Sports Nutrition 2007, 4:13
09-10-2008, 11:33 PM
Thats completely ****ed up, one guy had that happen and it was VERY likely not due to 6oxo in any part.
Ive used 6oxo many times, and believe it to be the best AI on the market, and 6oxo extreme to be the best legal pct available.
(as well as one of the safest, I believe it is about the only AI around that actually improves lipid profiles, don't quote me on that, but I'll try to find the study I'm thinking of... I know I knwo typically AI's are horrible on blood lipid profiles, but if I can find this study, I believe 6oxo is the exception)
09-11-2008, 12:16 AM
09-11-2008, 08:58 AM