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Old 06-26-2008, 01:39 PM   #1
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Arginine Alpha Ketoglutarate or Arginine ethyl ester

Anyone got any thoughts on which is the better?

Does dosage differ between the two to be effective.


Any thoughts please
 
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Old 06-26-2008, 02:02 PM   #2
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Both work good. In theory you should have to dose AEE lower.

White BLOOD = AEE / OEE
White FLOOD = AAKG / OAKG

O = Ornithine
 



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Old 06-26-2008, 02:50 PM   #3
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Esterification (as in arginine ethyl ester, AEE) or bonding with alpha ketoglutarate (as in arginine alpha ketoglutarate, AAKG) would promote absorption, stability, and bioavailability. But beyond this, alpha ketoglutarate has many other properties that esterification would not deliver. In particular, with an alpha-ketoglutarate bond, one would obtain all the endothelial-lining-support and vasoldilation properties of arginine plus a number of cool benefits of alpha ketoglutarate (AKG), such as more arginine stability, bioavailability and absorption. Furthermore, alpha ketoglutarate will serve as a transport medium for arginine, making it directly available at the cellular levels for optimal synthesis. Beyond this, alpha ketoglutarate improves the endogenous production of of glutamine and glutamic acid, both important for muscle growth and for the immune system. AKG also binds to toxic ammonia in muscle cells, in the liver, and in the brain, thereby converting ammonia into glutamic acid, improving glutamine levels and assisting in elimination of toxic ammonia from the body. Lastly, as a Krebs Cycle intermediate, AKG improves VO2 Max and energy metabolism in muscle cells, and is consequently a potent ergogenic.

Personally, I prefer the AAKG, not just because it is a more natural compound, but because it possesses several other important properties. More precisely, arginine bonded to any of the Krebs Cycle intermediate such as citrate, fumarate, malate, succinate, and alpha ketoglutarate, or compounds involved indirectly in the energy cycle, for instance, orotate, pyruvate, and so on, generally yields improved absorption, bioavailability, and potency.

In terms of dosing, it may help to recall that plain arginine has the property that it's absorption through the intestines is limited, causing arginine to be rapidly degraded, leaving only small quantities to produce the typical arginine effects. This is why you need to consume relatively more base arginine to see any results. Esterification or bonding with alpha ketoglutarate overcomes the typical arginine limitations, ensuring that arginine absorbs optimally and is available for its ergogenic properties. So, you basically need less of arginine ethyl ester (about 3g per dose) or arginine alpha ketoglutarate, (about 3g per dose) compared to base arginine to produce better results than base arginine.
 
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Old 06-26-2008, 02:57 PM   #4
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Strategicmove thanks for that .Very useful.
 
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Old 06-26-2008, 02:59 PM   #5
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Quote:
Originally Posted by strategicmove
Esterification (as in arginine ethyl ester, AEE) or bonding with alpha ketoglutarate (as in arginine alpha ketoglutarate, AAKG) would promote absorption, stability, and bioavailability. But beyond this, alpha ketoglutarate has many other properties that esterification would not deliver. In particular, with an alpha-ketoglutarate bond, one would obtain all the endothelial-lining-support and vasoldilation properties of arginine plus a number of cool benefits of alpha ketoglutarate (AKG), such as more arginine stability, bioavailability and absorption. Furthermore, alpha ketoglutarate will serve as a transport medium for arginine, making it directly available at the cellular levels for optimal synthesis. Beyond this, alpha ketoglutarate improves the endogenous production of of glutamine and glutamic acid, both important for muscle growth and for the immune system. AKG also binds to toxic ammonia in muscle cells, in the liver, and in the brain, thereby converting ammonia into glutamic acid, improving glutamine levels and assisting in elimination of toxic ammonia from the body. Lastly, as a Krebs Cycle intermediate, AKG improves VO2 Max and energy metabolism in muscle cells, and is consequently a potent ergogenic.

Personally, I prefer the AAKG, not just because it is a more natural compound, but because it possesses several other important properties. More precisely, arginine bonded to any of the Krebs Cycle intermediate such as citrate, fumarate, malate, succinate, and alpha ketoglutarate, or compounds involved indirectly in the energy cycle, for instance, orotate, pyruvate, and so on, generally yields improved absorption, bioavailability, and potency.

In terms of dosing, it may help to recall that plain arginine has the property that it's absorption through the intestines is limited, causing arginine to be rapidly degraded, leaving only small quantities to produce the typical arginine effects. This is why you need to consume relatively more base arginine to see any results. Esterification or bonding with alpha ketoglutarate overcomes the typical arginine limitations, ensuring that arginine absorbs optimally and is available for its ergogenic properties. So, you basically need less of arginine ethyl ester (about 3g per dose) or arginine alpha ketoglutarate, (about 3g per dose) compared to base arginine to produce better results than base arginine.
Great post (reps)
 
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Old 06-26-2008, 04:28 PM   #6
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Quote:
Originally Posted by strategicmove
Esterification (as in arginine ethyl ester, AEE) or bonding with alpha ketoglutarate (as in arginine alpha ketoglutarate, AAKG) would promote absorption, stability, and bioavailability. But beyond this, alpha ketoglutarate has many other properties that esterification would not deliver. In particular, with an alpha-ketoglutarate bond, one would obtain all the endothelial-lining-support and vasoldilation properties of arginine plus a number of cool benefits of alpha ketoglutarate (AKG), such as more arginine stability, bioavailability and absorption. Furthermore, alpha ketoglutarate will serve as a transport medium for arginine, making it directly available at the cellular levels for optimal synthesis. Beyond this, alpha ketoglutarate improves the endogenous production of of glutamine and glutamic acid, both important for muscle growth and for the immune system. AKG also binds to toxic ammonia in muscle cells, in the liver, and in the brain, thereby converting ammonia into glutamic acid, improving glutamine levels and assisting in elimination of toxic ammonia from the body. Lastly, as a Krebs Cycle intermediate, AKG improves VO2 Max and energy metabolism in muscle cells, and is consequently a potent ergogenic.

Personally, I prefer the AAKG, not just because it is a more natural compound, but because it possesses several other important properties. More precisely, arginine bonded to any of the Krebs Cycle intermediate such as citrate, fumarate, malate, succinate, and alpha ketoglutarate, or compounds involved indirectly in the energy cycle, for instance, orotate, pyruvate, and so on, generally yields improved absorption, bioavailability, and potency.

In terms of dosing, it may help to recall that plain arginine has the property that it's absorption through the intestines is limited, causing arginine to be rapidly degraded, leaving only small quantities to produce the typical arginine effects. This is why you need to consume relatively more base arginine to see any results. Esterification or bonding with alpha ketoglutarate overcomes the typical arginine limitations, ensuring that arginine absorbs optimally and is available for its ergogenic properties. So, you basically need less of arginine ethyl ester (about 3g per dose) or arginine alpha ketoglutarate, (about 3g per dose) compared to base arginine to produce better results than base arginine.
Great post! !!!!
 



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Old 06-27-2008, 03:44 AM   #7
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Why has no one ever thought about doing this witb Taurine or have they?
 
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Old 06-27-2008, 03:44 PM   #8
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and di arginine malate ???
 
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Old 06-27-2008, 10:09 PM   #9
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If you plan on taking the powder straight or non-capped, then one thing to note is that AAKG has virtually no taste, I have heard AEE tastes pretty bad.
 



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Old 06-28-2008, 01:43 AM   #10
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Quote:
Originally Posted by TOYFORDOLET
I have heard AEE tastes pretty bad.
that's putting it lightly... I'm trying to finish off 100g right now & it's killing me! Anybody out there, does this compare to yellow gold?
 



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Old 06-28-2008, 01:56 AM   #11
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Quote:
Originally Posted by strategicmove
Esterification (as in arginine ethyl ester, AEE) or bonding with alpha ketoglutarate (as in arginine alpha ketoglutarate, AAKG) would promote absorption, stability, and bioavailability. But beyond this, alpha ketoglutarate has many other properties that esterification would not deliver. In particular, with an alpha-ketoglutarate bond, one would obtain all the endothelial-lining-support and vasoldilation properties of arginine plus a number of cool benefits of alpha ketoglutarate (AKG), such as more arginine stability, bioavailability and absorption. Furthermore, alpha ketoglutarate will serve as a transport medium for arginine, making it directly available at the cellular levels for optimal synthesis. Beyond this, alpha ketoglutarate improves the endogenous production of of glutamine and glutamic acid, both important for muscle growth and for the immune system. AKG also binds to toxic ammonia in muscle cells, in the liver, and in the brain, thereby converting ammonia into glutamic acid, improving glutamine levels and assisting in elimination of toxic ammonia from the body. Lastly, as a Krebs Cycle intermediate, AKG improves VO2 Max and energy metabolism in muscle cells, and is consequently a potent ergogenic.

Personally, I prefer the AAKG, not just because it is a more natural compound, but because it possesses several other important properties. More precisely, arginine bonded to any of the Krebs Cycle intermediate such as citrate, fumarate, malate, succinate, and alpha ketoglutarate, or compounds involved indirectly in the energy cycle, for instance, orotate, pyruvate, and so on, generally yields improved absorption, bioavailability, and potency.

In terms of dosing, it may help to recall that plain arginine has the property that it's absorption through the intestines is limited, causing arginine to be rapidly degraded, leaving only small quantities to produce the typical arginine effects. This is why you need to consume relatively more base arginine to see any results. Esterification or bonding with alpha ketoglutarate overcomes the typical arginine limitations, ensuring that arginine absorbs optimally and is available for its ergogenic properties. So, you basically need less of arginine ethyl ester (about 3g per dose) or arginine alpha ketoglutarate, (about 3g per dose) compared to base arginine to produce better results than base arginine.
Posts like this make me love this guy....great post man.
 



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Old 06-28-2008, 02:07 AM   #12
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Quote:
Originally Posted by corsaking
Why has no one ever thought about doing this witb Taurine or have they?
I use both in my preWO shake, 5g Taurine and 4g AAKG, along with other bulk supps from NP.

Great post StrategicMove
 
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Old 06-28-2008, 04:37 AM   #13
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I'm thankful you found my contribution useful.
 
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Old 06-30-2008, 06:32 AM   #14
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Quote:
Originally Posted by strategicmove
Esterification (as in arginine ethyl ester, AEE) or bonding with alpha ketoglutarate (as in arginine alpha ketoglutarate, AAKG) would promote absorption, stability, and bioavailability. But beyond this, alpha ketoglutarate has many other properties that esterification would not deliver. In particular, with an alpha-ketoglutarate bond, one would obtain all the endothelial-lining-support and vasoldilation properties of arginine plus a number of cool benefits of alpha ketoglutarate (AKG), such as more arginine stability, bioavailability and absorption. Furthermore, alpha ketoglutarate will serve as a transport medium for arginine, making it directly available at the cellular levels for optimal synthesis. Beyond this, alpha ketoglutarate improves the endogenous production of of glutamine and glutamic acid, both important for muscle growth and for the immune system. AKG also binds to toxic ammonia in muscle cells, in the liver, and in the brain, thereby converting ammonia into glutamic acid, improving glutamine levels and assisting in elimination of toxic ammonia from the body. Lastly, as a Krebs Cycle intermediate, AKG improves VO2 Max and energy metabolism in muscle cells, and is consequently a potent ergogenic.

Personally, I prefer the AAKG, not just because it is a more natural compound, but because it possesses several other important properties. More precisely, arginine bonded to any of the Krebs Cycle intermediate such as citrate, fumarate, malate, succinate, and alpha ketoglutarate, or compounds involved indirectly in the energy cycle, for instance, orotate, pyruvate, and so on, generally yields improved absorption, bioavailability, and potency.

In terms of dosing, it may help to recall that plain arginine has the property that it's absorption through the intestines is limited, causing arginine to be rapidly degraded, leaving only small quantities to produce the typical arginine effects. This is why you need to consume relatively more base arginine to see any results. Esterification or bonding with alpha ketoglutarate overcomes the typical arginine limitations, ensuring that arginine absorbs optimally and is available for its ergogenic properties. So, you basically need less of arginine ethyl ester (about 3g per dose) or arginine alpha ketoglutarate, (about 3g per dose) compared to base arginine to produce better results than base arginine.
If I ever become half as smart/knowledgable as Strategic, I'll die a happy man!
 
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Old 07-02-2008, 10:49 AM   #15
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