riseboi
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[size=+4]riseboi dives skin deep into Primordial Performance's Dermatherm[/size]
I will be approaching this log differently than my previous two logs. Since this is unsponsored, I will post updates in a KISS style (Keep It Short & Simple). I guess you could say I'm shedding the fat (yes, pun intended). That is correct; no videos, quotes, or songs on his log. Anyways, there's too many copy cats out there.
Most of the detail of this log intro will be centered around the product description since I believe Primordial Performance has had little exposure on this forum. Other than that, my “before” pics will be the only other pertinent addition to this intro. As far as additional supplements I will continue with the usual stuff, and may be discontinue a few things; none of which I believe will have any pertinent effects on this log. However, since an increase in hunger has been noted by others who have used Dermatherm, I will probably use Applied Nutriceutical's Lipotrophin AM/PM to mitigate any issues with hunger. As I have never used them before, I will try and comment on their effectiveness if taken, but the primary focus of this log will remain on the effectiveness of DermaTherm. I will begin the log without the use of Lipotrophin AM/PM and add them as needed. Also, I believe my diet and workouts to be sound and you can find more details on them in my previous logs.Lastly, I will state that I have always been a bit leery of topical fat loss products, however, the products from Primordial Performance caught my eye, and the few reviews I did read about there products were favorable. With that said, I will approach this with an open mind. I'm already pretty lean, so I'm not expecting miracles, but because of the fact that I'm already pretty lean, I think I will be able to objectively note any favorable effects. Since the product descriptionis pretty long, I will end here, and add on any pertinent info in my updates.
”BEFORE” PICS
The following description is from their website. Due to forum rules I don't think I can list their website. For those interested, google is your friend.
[size=+2]PRIMORDIAL PERFORMANCE DERMATHERM[/size]
[size=+1]Product Overview[/size]
DermaTherm is a new revolutionary topical fat loss product. This is the first topical fat loss product on the market designed to burn fat over the entire body, rather than targeting a specific area. Dermatherm is free of any diuretics or stimulants which would only produce a “quick fix”. Instead, our formula creates a real thermogenic effect by increasing body heat and energy expenditure for powerful and noticeable fat loss.
Dermatherm is not only an effective fat loss formula, but an exciting and pervasive experience for the user. Immediately upon application, you will smell the pleasant aroma of the natural aromatics. Within minutes of application, you will feel the warm tingle sensation as the natural extracts pass through the skin. You will actually feel the incandescence take over the entire body as the active ingredients initiate a thermogenic response. Within days, your body will radiate with heat from the inside out as the metabolism ignites oxidation of stubborn fat tissue.
- DermaTherm is positively correlated to dramatically reduce fat mass while preserving muscle mass. By having thermogenic and anti-catabolic properties, Dermatherm will increase your metabolism and calorie burning without sacrificing strength and muscle.
- DermaTherm was created with natural flavonoids, alkaloids and hormones to create a powerful yet safe effect on thermogenesis. We created Dermatherm without any stimulants to avoid the typical jitters, anxiety, and sleeplessness asscoated with most fat loss products.
- By delivering the ingredients through the skin, and using our highly efficient OHV technology, the active ingredients become immediately bioavailable and timed released for even delivery throughout the day.
- For best results, use DermaTherm everyday for at least 4 weeks. For maximum fat loss, use DermaTherm along with a low calorie diet and exercise program.
[size=+2]Product Benefits[/size]
[size=+1]Thermogenic Boost[/size]
DermaTherm is positively correlated to dramatically reduce fat mass while preserving muscle mass. By having both thermogenic and anti-catabolic properties, Dermatherm will increase your metabolism and calorie burning without sacrificing strength and muscle.
Metabolic Optimization - Insulin sensitivity – fat loss
Improving insulin sensitivity and blood sugar levels is a vital part of preventing obesity and maintaining overall health. Two ingredients in DermaTherm are known to be powerful insulin sensitizers – Trans-cinnamaldehyde and evodiamine. Trans-cinnamaldehyde increases insulin sensitivity by inhibiting Protein Tyrosine Phosphatase (PTP1B) and increasing trans-phosphorylation of the insulin receptor, which magnifies the action of insulin, thus requiring a lower amount to control blood sugar. The combination of improving insulin sensitivity, lowering blood sugar, and inhibiting PTP1B, also improves leptin sensitivity. Improving the sensitivity of leptin allows for further improvements in energy management and appetite control, all while fighting the odds of becoming obese.
However, the main benefit of trans-cinnamaldehyde and evodiamine is their ability to increase energy and heat dissipation by acting as a powerful vasodilators. A study with animals who were given evodiamine with a high calorie diet burned significantly more fat mass than the control group. The evodiamine group also had double the lipolytic (fat burning) activity in fat tissue and improved cholesterol values. These benefits were accomplished without any toxic effects. Since we were set on releasing one of the most thermogenic formulas on the market we found three more thermogenic compounds which acted synergistically to create the most unique formula on the market.
Maximimum Themogenesis - energy induction & calorie consumption
Most of you who understand the metabolic process of fat loss realize that thyroid hormones such as T4 and T3 plan an important role in oxygen consumption and energy metabolism. Anyone interested in becoming truly lean must maintain high levels of these thyroid hormones. DermaTherm accomplishes this by including Kaempferol, a natural flavonol with the ability to increase T3 production. Kaempferol effectively up regulates the cellular 2 iodothyronine deiodinase (D2) enzyme and increases the conversion of T4 > T3. In fact, by increasing the enzyme activity and half-life of D2, Kaempferol can increase T3 production as much as 260% (even after kaempferol is excreted from the system!). Other metabolic pathways are also positively influenced by kaempferol, such as the peroxisome proliferator–activated receptor, carnitine palmitoyl transferase-1, mitochondrial transcription factor 1, and uncoupling protein-3.17
Thermogenesis is further intensified by the hormone 7-keto DHEA. This hormone is a true thermogenic monster which increases oxidation (calorie burning) by increasing glycerol-3-phosphate, mitochondrial malic enzyme activity in the liver, and by mimicking thyroid hormone (T4/T3) and increasing protein uncoupling and proton leak across the mitochondrial membrane. A study with men and women on a calorie restricted diet showed that 8 weeks of 7-keto DHEA supplementation tripled the rate of fat loss compared to a placebo group. These results have been confirmed by other human and animal trials, with no adverse effects seen from 7-keto DHEA supplementation.
The synergistic effect from these powerful thermogenics will dramatically ramp up oxygen consumption and heat production. The fat loss is further synergized by enhancing the availability of fat to the cell powerhouse – the mitochondria. DermaTherm accomplishes this by including raspberry ketone, which increases activity of hormone sensitive lipase which is the hormone that breaks down fat to enhance lypolysis (fat burning). This way you know you are making your body fat readily available for rapid fat loss.
Preserving Muscle - Cortisol control
A significant “side benefit” to the potent dose of 7-keto DHEA in DermaTherm is its ability to antagonize the nasty catabolic effect of cortisol. Cortisol is a glucocorticoid which breaks down muscle mass for glucose (energy) when calorie consumption is low. This is a reason why many individuals become “skinny fat” after losing considerable weight from dieting. A reduction in calories causes a spike in cortisol and a rapid breakdown of muscle mass (instead of fat mass). 7-keto DHEA prevents this muscle breakdown by blocking cortisol, and allowing fat to be burned for energy instead. Preserving muscle and targeting fat loss is the key to obtaining that toned and lean physique that seems impossible to find.
Additionally, cortisol can also degrade and impair your immune system, but again, 7-keto DHEA can help prevent this. Protecting your immune system is a vital part of warding off sickness during hardcore dieting and staying on the track to success.
[size=+2]Active Ingredients[/size]
[size=+1]Proprietary blend[/size]
Evodiamine
Evodiamine is a quinozol alkaloid extracted from the Evodia fruit. It shares similarity with capsaicin (hot pepper extract) by acting upon the same vanillioid receptor, and activating the sensory nerves, but without the same irritating pungency. By activating the sensory nerves, evodiamine increases energy and heat production. This also creates a vasodilatory effect which increases blood flow and heat dissipation making evodiamine a powerful thermogenic. Animals studies have shown evodiamine to be a potent fat loss compound. More recently, evodiamine has been under intense research for its inhibitory effects on prostate and cervical cancer.
7-Keto DHEA
7-keto DHEA is a hormone and metabolite of DHEA, but without any androgenic or estrogenic effects. 7 7-keto DHEA serves to enhance immune system function by countering the immuno-suppressive effects of cortisol, but it also acts as a powerful thermogenic. 7-keto DHEA increases oxidation (calorie burning) by increasing glycerol-3-phosphate and mitochondrial malic enzyme activity. There is also evidence that 7-keto DHEA increases thermogenesis by mimicking thyroid hormone (T4/T3) and increasing uncoupling proteins and proton leak across the mitochondrial membrane. 7-keto DHEA has been well researched for its fat loss effects in animals & humans and has proven to be both safe and effective.
Kaempferol
Keampferol is a flavonol which positively modulates metabolic pathways within human skeletal muscle. Treatment with kaempferol can increase myocyte oxygen consumption in muscle as much as 30% by increasing cAMP generation and protein kinase A. More specifically, kaempferol up regulates the cellular 2 iodothyronine deiodinase (D2) activity and causes a dramatic increase in the rate of T3 production. When compared to other similar flavonoids such as quercetin and fisetin, kaempferol was the most powerful inducer of D2 activity. As a light weight polyphenolic molecule, keampferol readily absorbs through the skin.
Raspberry Ketone
Raspberry ketone is a small aromatic molecule extracted from raspberries, which is known to give raspberries their pleasant smell. Raspberry ketone is also known to have powerful fat burning ability in both white and brown adipose tissue by increasing fat utilization within the mitochondria. This effect is created by increasing transport of hormone-sensitive lipase in to the cell, which increases norepinephrine induced fat burning.
Trans-Cinnamaldehyde
Trans-cinnamaldehyde is a natural oil extracted from the bark of cinnamon which shares many of the same properties as whole cinnamon. Trans-cinnamaldehyde has been used to treat high blood pressure, digestive disorders, and has even been researched for use in inhibiting growth of tumors and cancer cells. We included trans-cinnemaldehyde for it's powerful vasodilatory and insulin sensitizing effects.
[size=+2]Superior Delivery[/size]
[size=+1]Absorption by the skin[/size]
Like our other topical based products, DermaTherm utilizes our exclusive OHV based delivery system, but with one modification. Dermatherm is enhanced with two extreme vasodilatory compounds known as trans-cinnamaldehyde and evodiamine. These natural extracts rapidly dilate the blood capillaries at the skins surface. The heat created by these powerful vasodilators helps create a kinetic force which actively moves the ingredients across the skin and into the blood steam. With trans-cinnamaldehyde and evodiamine acting as both a metabolic booster, and an active carrier, we have created a unique synergy for topical based fat loss.
Another ingredient in Dermatherm, which has minimal activity as an oral supplement, is 7-keto DHEA. Using this compound in an topical delivery system dramatically increases its bioavailability and thermogenic potential. The skin creates the perfect timed release depot for 7-keto so levels are kept high all day long, after just one application. What's even more exciting is that 7-keto is the precursor to an even more thermogenic fat burning hormone known as 7-beta DHEA. When 7-keto passes the skin, much of it interacts with the hormonal enzyme CYP11B1, which rapidly converts the 7-keto to 7-beta DHEA.
We separate DermaTherm from the competition by coupling the most advanced topical formula on the market with the highest potency pharmaceutical grade ingredients.
[size=+2]How To Use[/size]
[size=+1]Dosage & Application[/size]
Administer 8 sprays or 1 pump* per 20lb of bodyweight and apply the illustrated application site. The application figure to the right shows the number of pumps applied to a 220lb user.
For example:
- A 220lb user would apply 88 sprays or 11 pumps for one application. For this person, a bottle of DermaTherm would last about 14 days.
Or
- A 120lb user would apply 48 sprays or 6 pumps for one application. For this person, a bottle would last 25 days.
*For user convenience, DermaTherm is included with two different “pumps” for application. We highly recommend the lotion style pump for the easiest application.
If using the trigger sprayer – Spray dose into hand and rub thoroughly onto the body over the illustrated application area. If trigger sprayer clogs, put tip under warm running water.
If using the lotion pump – Pump dose into hand and thoroughly rub into the body over the illustrated application area. We recommend this pump for fastest application. During travel, it is best to cap the product with the original cap shipped with the product. Also, use this cap if storing product for longer than a month.
Only apply the product to clean, dry skin. Shower and exfoliate skin with body-scrubber to remove dead skin cells and optimize absorption. When applying the product, spread across skin quickly to cover as much surface area as possible before product dries. Shaving off body hair is recommended, but not required. However be careful to avoid razor burn as this could be irritated by the DermaTherm. Also, avoid swimming or bathing for at least 6 hours after application.
Note: Immediately after application, DermaTherm may leave the skin warm, red or slightly itchy for approximately 1-2 hours. This is normal, but should not be painful, or persistent for anymore than 3-4 hours. Spot test a small area of skin to assess tolerance. DO NOT USE PRODUCT IF SKIN BECOMES DRY, FLAKY OR PAINFULLY IRRITATED.
For best results, use DermaTherm everyday for at least 4 weeks. For maximum fat loss, use DermaTherm along with a low calorie diet and exercise program. It is best to stack DermaTherm with an appetite suppressant or “energy” supplement to help control appetite and to provide additional energy while on a calorie deficient diet.
Remember, DermaTherm will increase body temperature which may cause an increase in water retention. Don’t be alarmed if your bodyweight increases 1-2 lbs the first week or two. Also, DermaTherm will have an anti-catabolic effect which will prevent muscle loss, so significant reductions in total weight loss are unlikely when using this product. For this reason, it is important to watch the bodyfat % rather than scale wieght to get an accurate reading of results. (allow 3-4 days for excess water weight to be expelled after discontinuing DermaTherm)
Caution: The DermaTherm topical formula contains ingredients that temporarily increase photosensitivity (3-4hr) and increase chance of sunburn. Therefore, caution is advised for those applying the product immediately before direct UV exposure. Also, be sure to wash hands after application and AVOID product contact with eye’s, mouth and genitals.
