Alright, so today was day one with 4 caps! I downed two first thing this morning and two this afternoon. I am hoping to see some relief of my right wrist pain and my nagging left shoulder during this test period. I know there is definitely Cissus in this product so I will enjoy the anti-inflammatory properties of that as I avoid NSAIDS like the plague. The damage to muscle building and your stomach and liver is enough to keep me away. Not expecting too much this first week but the cissus has shown some relief for me starting in the second week.