MuscleGuyinNY
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I just came across this and was wondering if anybody, especially those who have used 1-AD, can chime in. Just curious:
"Just the facts about 1-AD
Q: I’ve been hearing about a new pro-hormone supplement called 1-AD. It’s supposed to be seven times more powerful then testosterone, with none of the usual side effects. What do you think about this stuff?
A: I think ErgoPharm’s marketing department should be congratulated. Using classic guerilla marketing techniques (i.e., posting multiple commentaries about 1-AD on a variety of bodybuilding chat sites and message boards) ErgoPharm, in cooperation with LPJ Research Inc., has done a great job at turning an interesting product concept into a virtual urban legend. Without making claims for which they could be held liable, they have managed to insinuate exactly the information you mentioned above. And to many people this has become fact. But, what are the facts, really?
Fact #1: Patrick Arnold, who is the president of LPJ and brains behind this product development, is clearly a bright guy with a vast history in and a passion for pro-hormone supplement development.
Fact #2: 1-AD (1-androstene-3beta, 17beta-diol) is a metabolic precursor to 1-testosterone.
Fact #3: 1-testosterone is chemically very similar to testosterone, and cannot be aromatized to estrogen due to the small difference in structure.
Fact #4: 1-testosterone has been shown—in one preliminary study back in the 1960s—to possibly be 700 percent more myotrophic (anabolic) than testosterone.
Fact #5: Due to its chemical structure, 1-AD would be more resistant than most pro-hormones to being broken down in the liver—thus making it more likely to be orally active.
Fact #6: 1-testosterone is even more chemically and metabolically similar to dihydrotestosterone (DHT—the stuff that promotes prostate enlargement and hair loss) than it is to testosterone.
Fact #7: 1-AD can freely convert to DHT in the body.
Fact #8: There is no conclusive research demonstrating that 1-AD converts to 1-testosterone when taken orally by humans.
Fact #9: 1-testosterone, while possibly highly anabolic, is similarly highly androgenic.
Fact #10: Real world muscle building effects of 1-testosterone have never been scientifically demonstrated in humans.
Fact #11: No human research has of yet been done to assess the actual chemical and anabolic effects of taking 1-AD.
Fact #12: Fairly severe GI and urinary side-effects have been noted by users of 1-AD.
Fact #13: At its cheapest a month supply of 1-AD would cost you $180.
End analysis: This is an interesting product concept with no direct scientific support of its effectiveness. If and when they get some research going to demonstrate that 1-AD does indeed convert to 1-testosterone when taken orally, and that this 1-testosterone truly does stimulate muscle growth, and that the probable conversion to DHT can be controlled, and that other hormonal systems aren’t adversely affected it may be worth trying. Until then, I’d spend your hard-earned cash elsewhere."
This is on the EAS website, in case any of you are wondering.
If 1-AD is an all-natural precursor to Test, then why would there be any need to worry about having a SERM, instead of just using something like AI's Cycle Support and Post Cycle Support? ErgoPharm states that the possible sides of DHT (i.e. hair loss) are very slim to none, there is no water-retention, and zero chance of any aromatization.
"Just the facts about 1-AD
Q: I’ve been hearing about a new pro-hormone supplement called 1-AD. It’s supposed to be seven times more powerful then testosterone, with none of the usual side effects. What do you think about this stuff?
A: I think ErgoPharm’s marketing department should be congratulated. Using classic guerilla marketing techniques (i.e., posting multiple commentaries about 1-AD on a variety of bodybuilding chat sites and message boards) ErgoPharm, in cooperation with LPJ Research Inc., has done a great job at turning an interesting product concept into a virtual urban legend. Without making claims for which they could be held liable, they have managed to insinuate exactly the information you mentioned above. And to many people this has become fact. But, what are the facts, really?
Fact #1: Patrick Arnold, who is the president of LPJ and brains behind this product development, is clearly a bright guy with a vast history in and a passion for pro-hormone supplement development.
Fact #2: 1-AD (1-androstene-3beta, 17beta-diol) is a metabolic precursor to 1-testosterone.
Fact #3: 1-testosterone is chemically very similar to testosterone, and cannot be aromatized to estrogen due to the small difference in structure.
Fact #4: 1-testosterone has been shown—in one preliminary study back in the 1960s—to possibly be 700 percent more myotrophic (anabolic) than testosterone.
Fact #5: Due to its chemical structure, 1-AD would be more resistant than most pro-hormones to being broken down in the liver—thus making it more likely to be orally active.
Fact #6: 1-testosterone is even more chemically and metabolically similar to dihydrotestosterone (DHT—the stuff that promotes prostate enlargement and hair loss) than it is to testosterone.
Fact #7: 1-AD can freely convert to DHT in the body.
Fact #8: There is no conclusive research demonstrating that 1-AD converts to 1-testosterone when taken orally by humans.
Fact #9: 1-testosterone, while possibly highly anabolic, is similarly highly androgenic.
Fact #10: Real world muscle building effects of 1-testosterone have never been scientifically demonstrated in humans.
Fact #11: No human research has of yet been done to assess the actual chemical and anabolic effects of taking 1-AD.
Fact #12: Fairly severe GI and urinary side-effects have been noted by users of 1-AD.
Fact #13: At its cheapest a month supply of 1-AD would cost you $180.
End analysis: This is an interesting product concept with no direct scientific support of its effectiveness. If and when they get some research going to demonstrate that 1-AD does indeed convert to 1-testosterone when taken orally, and that this 1-testosterone truly does stimulate muscle growth, and that the probable conversion to DHT can be controlled, and that other hormonal systems aren’t adversely affected it may be worth trying. Until then, I’d spend your hard-earned cash elsewhere."
This is on the EAS website, in case any of you are wondering.
If 1-AD is an all-natural precursor to Test, then why would there be any need to worry about having a SERM, instead of just using something like AI's Cycle Support and Post Cycle Support? ErgoPharm states that the possible sides of DHT (i.e. hair loss) are very slim to none, there is no water-retention, and zero chance of any aromatization.
