To increase oral availability, I know.
The sublingual is pointless for a 17a-oral. Most of an SD cap is filler and very little, if any, would dissolve under your tongue.
There is, but it's a pain in the ass and not worth the time.
Might taste bad, but there is not extra danger.
I tried it yesterday. The taste wasn't bad at all -- almost sweet. And it seemed like I got almost all of it to absorb under my tongue. Just a tiny bit of leftover rubbery residue (filler?) that I swallowed. So maybe this will spare my liver at least a little abuse -- who knows?
sorry, I'm not a chemistry, but you can take, example, cocaine sublingual or snuff it, same effect.
I dunno, but I feel a "different-feeling" in this way and I'm not a "easy-placebo-boy" ever with other recreational drugs...
some of the superdrol is probably going sublingual, but why does it matter? Aside from the fact that most is just rolling down the back of your throat, whether you notice or not, what is the point? Your liver still takes a beating either way. This is like injecting SD, it will still pass through your liver, since the liver still filters your blood.
I'm no expert at all, but I thought it was that "first pass" through the liver that did all the damage with the methylated compounds.
all you are doing is delaying the first pass, not bypassing it. IF any is going sublingual, all you might do is increase potency by a percent or two, but realistically, it just mixing with saliva and going down your throat. It will still make a first pass through the liver, and then a second pass causing the same amount of damage.
no. Imagine you took the 17aa out of dianabol, you would get boldenone, aka equipoise. Two very different effects with only a slight modification. 17aa really changes the dynamics and effects of steroids.
Oh. I thought the 17aa was only there to increase bio-availability. I figured it would be the same compound without the 17aa, it just wouldn't be bio-available. That's why I love this place -- there's plenty of knowledgeable people here, and I learn something new every day. Thanks Aspire.
Masteron is a scheduled substance. Sub-lingual isn't that efficient either, you would have a lot of wasted product. Really, cyclo-dextrin would be a better method, but generally hurts. Pinning really isn't that big of a deal once you get past the mental block of it.
I don't have any mental block. I'm not afraid of needles or blood. (I frequently check my cholesterol with those finger-prick home kits.) It's just that pinning is a fairly involved, messy, difficult to travel with, process. Pills are so much more convenient. I really would love to see some new products developed specifically for sublingual administration. I think it has distinct advantages over both oral and injectable methods. Are you listening, company reps?
Thats basically a cyclodextrin. Except it has to do with permeability into the mucus membranous since steroids can't cross it normally.
OK, then just humor me and try it. Take one of your capped supps (preferably small cap/fine powder), swallow most of your saliva first, then open the cap and pour it under your tongue. As your mouth starts to generate saliva, start moving your tongue around a bit, and push down on the powder, as if you're trying to force it into the tissue -- under the tongue, into the gums, roof of your mouth, wherever it ends up (but try to keep most of it under your tongue). And refuse to swallow for as long as you can. Gradually, the grit of the powder will disappear and the taste will fade. I believe this is a pretty good indication that it's absorbing into your oral tissues. Let me know what you think.
Ok, lets say its 100% absorbed. With a methyl steroid most oral absorption is 95%+ anyway. So lets go with non methylated hormones. Since molecular weight could be a problem with absorption and the esters could affect permeability, so we should use base hormones. But base hormones have the problem of a short half life, so this would require multiple times a day dosing. Just being realistic, its not optimal.
Isn't short half life optimal for pulse cycles? That's why you dose once immediately pre-workout, and then again immediately post-workout.
When I say short for base compounds, I mean like minutes. The half life of test in the body is somewhere along the lines of like 9 minutes.
I guess that could be a problem, lol.
tren base, or even acetate. I don't know if the ester is cleaved though, but I doubt it.
Hey, I bet I could find some of that, if I wanted to. But I know nothing of "real gear," so I'll have to do some homework.
I'll pass on the suppository, lol. But I do think sublingual is an under-used delivery method. You don't have to methylate it (saving your liver from much abuse); it's much cleaner than transdermal delivery; and it's much more convenient than injections. Any opinions from the company reps about manufacturing sublingual products???
No, it's not gentler on the liver. The entire amount still has to be metabolized by the liver.
Catch up? I just saw the thread and noticed that nobody had yet informed the guy that he's clueless about metabolism. I wasn't catching up. Just cleaning up after you guys.:rasp:
