Norandrostenedione and anti-estrogenic properties

  1. New Member
    neurotic's Avatar
    Join Date
    Apr 2003
    Posts
    124
    Rep Power
    205
    Level
    10
    Lv. Percent
    16.94%

    Norandrostenedione and anti-estrogenic properties


    What do you think about this statement by Bill Roberts?

    "Norandrostenedione can be converted to estrone by aromatase, but is a very poor substrate for that enzyme. It can actually act as a competitive inhibitor, blocking better substrates such as androstenedione or testosterone. It is possible then, though unproven, that norandrostenedione might have some value as an aromatase inhibitor in bodybuilding."

    Do you think that it could be deduced from this statement that Nordione is less likely to produce estrogenic side effects than nordiol?

  2. New Member
    Blacksmith's Avatar
    Join Date
    Dec 2002
    Posts
    87
    Rep Power
    190
    Level
    8
    Lv. Percent
    83.36%

    Originally posted by neurotic
      Do you think that it could be deduced from this statement that Nordione is less likely to produce estrogenic side effects than nordiol?
     

    Nor-diol, because it is a diol does not a convert to estrogen prior to coversion to the target hormone nandrolone. Since 19nor converts to the same target hormone and may aromatase before conversion, I would say the dione has the greater potential. Although since the conversion rate of nor-diol is higher, you might get fooled into thinking the aromatase of the target hormone is higher from the nordiol.

     

Similar Forum Threads

  1. PCT info and anti-estrogen pill
    By bpeck in forum Post Cycle Therapy
    Replies: 23
    Last Post: 03-14-2013, 12:47 AM
  2. AI's and anti-estrogen questions...
    By Go Away in forum Anabolics
    Replies: 11
    Last Post: 03-28-2012, 01:15 PM
  3. Replies: 0
    Last Post: 03-01-2010, 05:27 PM
  4. Replies: 0
    Last Post: 04-29-2009, 11:27 PM
  5. Replies: 22
    Last Post: 04-21-2006, 12:59 AM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
Log in