awmcdon
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We all know that methylated steroids are hard on the liver. But all hormones must be metabolized by the liver via either phase II sulfation or phase II glucuronidation.
Suppose bodybuilder X is taking 400mg of a unmethylated prohormone(for instance 3-AD) and 400mg of trione a day (Which has a typical steroid ring structure).
That is 800mg of steroid molecules the liver has to metabolize EVERY DAY or 5600mg a week.
Now suppose bodybuilder Y is taking 300mg of tren a week, 40mg of Dianabol a day and rebound reloaded.
We now have only 580mg of steroids to metabolize a week, almost 1/10th.
So I hope everyone can now see what I'm getting at. Considering the doses that some of these prosteroids and prohormones must be taken at, what is the long term potential for liver problems. Would it equal that of methylated hormones.
I believe this is an important issue that needs to be discussed. I haven't seen much talk on the site about the possibilty of liver toxicity with these high dose hormones. Most people just assume because its not a methyl its OK. That may be the case. I don't know.
So please anyone with any information about this topic please share.
Suppose bodybuilder X is taking 400mg of a unmethylated prohormone(for instance 3-AD) and 400mg of trione a day (Which has a typical steroid ring structure).
That is 800mg of steroid molecules the liver has to metabolize EVERY DAY or 5600mg a week.
Now suppose bodybuilder Y is taking 300mg of tren a week, 40mg of Dianabol a day and rebound reloaded.
We now have only 580mg of steroids to metabolize a week, almost 1/10th.
So I hope everyone can now see what I'm getting at. Considering the doses that some of these prosteroids and prohormones must be taken at, what is the long term potential for liver problems. Would it equal that of methylated hormones.
I believe this is an important issue that needs to be discussed. I haven't seen much talk on the site about the possibilty of liver toxicity with these high dose hormones. Most people just assume because its not a methyl its OK. That may be the case. I don't know.
So please anyone with any information about this topic please share.