My thought would be pgf2a's short half life (15 minutes). I would guess the dmso is there to ensure it gets through the skin and reaches fat cells before it is metabolized away.
I would love to see how this works in to areas.
First is fat reduction I'm sure if it gets the pgf2a through quick enough it will work great.
Second is for guys with super low bf. I am curious if this will help with spot growth if it gets directly to the muscle.