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Old 03-21-2007, 10:43 PM  
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How to "pulse" orals

A lot of guys have been asking me to clarify the theory behind this cycling technique, so here's a basic explanation.


What is "pulse" cycling? Pulsing is a method of dosing that is intentionally designed to avoid potential long-term side effects such as HPTA suppression and liver stress. This technique was originally developed in an effort to prevent the usual HPAA suppression experienced during long-term corticosteroid therapy in children. With pulse therapy, it was observed that the serious long-term side effects of chronic oral treatment were often prevented, and the short-term side effects like acne and mineral retention were typically much milder. This can also allow for higher doses to be used since the dosing is less frequent. Starting with this template, if one normally takes a product at 30 mg/day, that equals a total intake of 210 mg/week. While pulsing, one might typically take 40 mg of that same product on work out days only, 3 times per week. That calculates to 120 mg/week total, which is 90 mg less than usual. This provides the needed benefits of the product at arguably the most crucial metabolic times, which are just before and just after a work out. This offers a means of possibly attenuating the endocrine suppression that one might otherwise encounter on a standard cycle. In many cases, a conventional post cycle therapy should not be required after a typical 4 week pulse. However, while pulses of 6-8 weeks are permissible, a conventional post cycle therapy may still be prudent for some individuals. Idiosyncrasy seems to play a big role in regard to tolerance of duration, so general predictions obviously become tricky as duration increases.

Theoretically, if one doses every day in perfectly spaced intervals, one should achieve 100% effects, 100% short-term sides, and 100% long-term sides. If one doses every other day like the pulse protocol, one might better anticipate 60% effects, 75% short-term sides but only about 40% of the long-term sides. This means that if one would have gained 10 pounds on a standard 1 month cycle, one might instead only gain about 6 pounds per month pulsing. Since the time on is roughly only half when pulsing, the total length of the cycle can be doubled to basically 2 months. Using the same calculation, the net result would be a gain of 12 pounds over 2 months, instead of the 10 pound gain expected from the 1 month standard cycle. That means a greater net gain of 2 pounds per cycle, and perhaps a more permanent gain due to the slower rate of acquisition and longer time of reinforcement! For this reason, pulsing can be very economical on the body as well as the wallet, and offer a desirable alternative for conservative veterans just looking to stay in shape, or potential new comers exploring additional safety measures.

There are three common types of pulse:
1) EOD dosing (3-4 times per week)
2) 2 days on / 2 days off
3) 2 weeks on / 2 weeks off (2 wks is the longest viable on time consideration, no longer)

Depending on one's workout schedule, one of these options may offer optimal pulsing efficiency. On average, effective doses may typically be around 1.5x the normal daily dose of a standard cycle, and these doses are taken very close to one other. It's not essential that the last dose be administered before 6 pm, but the earlier the better for reducing suppression potential. Half the total dose can be taken pre work out, and the other half taken post work out. If an odd numbered dose is used, the greater of the 2 doses might best be taken pre work out. However, when pulsing non-methylated or fast acting supplements, the greater dose would instead be best utilized post work out based on half-life considerations. Individuals who are extremely sensitive to shutdown may even prefer to take the entire dose pre work out. When pulsing, dosing at least 3 day per week but not more than 4 day per week should foster optimal results.

There are a few miscellaneous nutrition considerations that would be wise to keep in mind. Having a quality, high carb/calorie post work out meal (or shake) is important to proper recovery, and ingesting sufficient protein especially on the off days doesn't hurt either. A cortisol antagonist like low dose DHEA (25-50 mg) may be helpful for slow healers or hard gainers. Some studies show that cortisol peaks in the morning and again in the mid afternoon, which might therefore be the ideal times for an anti-cort. An herbal or AI based test-boosting supplement used nightly (or at least on one's off nights) might prove very effective as additional insurance to discourage the possibility of suppression. SERMs with long half-lives probably require extra consideration and caution. One may observe that testicular volume and/or testosterone levels reset slightly above previous baseline at the end of 2 consecutive off days, or at the end of the cycle itself. This phenomenon is called 'bounce' back. This seemingly paradoxical bounce appears to reflect the body's short-term homeostasis effort, and acts somewhat like a built-in pct with this method. It's also good to remember that the smaller number of dose exposures likely means faster liver clearance of your supplement. Liver ancillaries (like healthy oils and anti-oxidants) are not contraindicated, but Milk Thistle in high doses could act counter productive to gains. Therefore, if you elect to use liver protectants, reserving them for off days only might be good middle ground. As always, I suggest that one only consider using legal, commercially available nutritional supplements, and always consult a physician prior to use of any supplement. Cycle safe!


Example of a 3x/wk pulse M,W,F:

Week-Dose(mg)
1 (10,20,30)
2 30
3 30-40
4 30-40
5 30-50
6 30-50
7 30-60
8 30-60

Example of a 4x/wk pulse Sat, Sun, Wed, Thur:

Week-Dose(mg)
1 (10,20,30,30)
2 30
3 30-40
4 30-40
5 30-50
6 30-50



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Last edited by DR.D; 08-12-2007 at 01:49 AM.
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Old 03-21-2007, 10:45 PM  
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great post
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Old 03-21-2007, 10:56 PM  
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This almost sounds too good to be true.

Not doubting the legitimacy, but would you care to provide any sources so I can intelligently comment on your post?
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Old 03-21-2007, 11:17 PM  
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what do you think about pulsing for a month and then take it every day for a month im thinking of doing this. ive bee on epi for 3 days and might just start pulsing for a month
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Old 03-21-2007, 11:29 PM  
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Quote:
Originally Posted by RoboGiblets
This almost sounds too good to be true.

Not doubting the legitimacy, but would you care to provide any sources so I can intelligently comment on your post?
What do you mean sources? I pioneered this method myself! Back in the late 80's there was no such thing as PCT. You had to be smart to keep your balls and your gains back then. It wasn't as easy as it is now. Like I did reference in the post though, this method is derived from corticosteroid pulsing techniques used in kids and that's an easy search away. If you do decide to try it, this is what I have found works with greatest efficiency.



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Old 03-21-2007, 11:29 PM  
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Quote:
Originally Posted by RoboGiblets
This almost sounds too good to be true.

Not doubting the legitimacy, but would you care to provide any sources so I can intelligently comment on your post?
your concerns are certainly very valid.

people in the community have been using the "morning dbol" technique for decades to avoid complete suppression and still make gains that naturally wouldnt be possible. morning dbol is typically done on an ED basis, and the dose is low...those are the real differences, but the idea is similar: reduced gains with reduced sides, and possible shutdown avoidance.

so is it for real? i think i've seen a clinical study that showed that small amounts of anavar are suppressive when used ED...and maybe bloodwork that showed that a guy using morning dbol had good blood test results, but no data on suppression.

worth looking into.

my 2cc: i used "morning tbol" @ 20mg for 30 days, with no other steroids. i had an increase in libido that dropped LOW as soon as i came off...suggesting that i was in fact suppressed. i did do PCT afterwards of course, and came back to square after about a week.

if this pulse method works, as verified by bloodwork, i would be the first in line as i am always looking to reduce sides, avoid suppression and still make gains.

and i personally think the issue of "pre-WO versus 1st thing AM" for suppression minimization deserves some discussion....
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Old 03-21-2007, 11:30 PM  
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Quote:
Originally Posted by jaydesiel4651
what do you think about pulsing for a month and then take it every day for a month im thinking of doing this. ive bee on epi for 3 days and might just start pulsing for a month
I suppose you could, but I don't see what your goal is exactly? Don't complicate things the first time!



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Old 03-21-2007, 11:59 PM  
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Are there any orals that you would advise against when pulsing?
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Old 03-22-2007, 12:13 AM  
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Quote:
Originally Posted by DR.D
I suppose you could, but I don't see what your goal is exactly? Don't complicate things the first time!
Nicely put D.....



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Old 03-22-2007, 12:21 AM  
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Pulsing is a sweet idea... I may try this during the summer because the 8 weekers would last the majority of my summer which would be nice!



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Old 03-22-2007, 12:53 AM  
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Quote:
Originally Posted by johnnyfats
Are there any orals that you would advise against when pulsing?
Not that I can think of. It's a great way to attenuate toxicity and delay suppression with really nasty stuff like M1T and also a cool way to basically avoid suppression with very clean compounds like Epi. Things like Epi and Dbol actually increase LH initially, so pulsing is almost like having 3 initial doses every week instead of just at the beginning of a cycle. In fact, several guys have done this with Epi (like mfoley) at up to 60mg and reported excellent results. He followed with MFX with a little ATD now just for the heck of it, but more as a bridge than a PCT. He said he never crashed and was always going to pulse from now on.

My average test level was 750 from ages 16-19 (when I was pulsing.) 2 years later when I was in college and no longer cycling, it averaged 850. I have 3 kids also so there was no long term fertility issues or loss of test production with me! It's a good method. Start low and slow following these basic principles and work your way into it over time to see how your body responds. If you hate losing your gains and crashing in PCT, this is something you may wanna try. If you do it right, your test production can end up being higher after it's over and you'll never need a SERM again, just a little test booster at the most.



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Old 03-22-2007, 02:23 AM  
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What about pulsing dbol while on a test cycle. Instead of kickstarting the cycle with dbol for 4 weeks, you could then pulse dbol for 6-8 weeks or so. What kind of effect would this have?
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Old 03-22-2007, 05:33 AM  
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Quote:
Originally Posted by gators52
What about pulsing dbol while on a test cycle. Instead of kickstarting the cycle with dbol for 4 weeks, you could then pulse dbol for 6-8 weeks or so. What kind of effect would this have?
Your thread got me thinking.
I wonder how Dbol would stack with Havoc in a sort of pulse cycle.
Dbol EOD at low dose and Havoc on the opposite days. You would see gains from both and Havoc would keep the "Dbol bloat" to a minimum.
I realize this would still shut you down but it would be less stressfull on your liver than running them side by side and you should be able to keep gains better than a Dbol only cycle.

Any thoughts?
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Old 03-22-2007, 06:23 AM  
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Thumbs up

Bless you Dr. D !
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Old 03-22-2007, 06:38 AM  
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Quote:
Originally Posted by DR.D

Example of a 3x/wk pulse M,W,F:

Week/Dose(mg)
1 (10,20,30)
2 30
3 30-40
4 30-40
5 30-50
6 30-50
7 30-60
8 30-60

Example of a 4x/wk pulse Sat,Sun & Wed,Thur:

Week/Dose(mg)
1 (10,20,30,30)
2 30
3 30-40
4 30-40
5 30-50
6 30-50
Dr. D,

Just to clarify, your ranges in doses above such as 30-40 or 30-50 are listed as such to allow for people to apply your suggestions and take their age, weight, cycling experience, etc etc. into consideration when chosing what dose to run with, correct?

Also, if one was running a 3-day training split, such as a M-W-F protocol, do you feel that the 3x/wk pulse would be optimal?

Thanks!
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Old 03-22-2007, 08:31 AM  
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Quote:
Originally Posted by Jmuls
Dr. D,

Just to clarify, your ranges in doses above such as 30-40 or 30-50 are listed as such to allow for people to apply your suggestions and take their age, weight, cycling experience, etc etc. into consideration when chosing what dose to run with, correct?

Also, if one was running a 3-day training split, such as a M-W-F protocol, do you feel that the 3x/wk pulse would be optimal?

Thanks!
YES! to both questions............

Awesome posts, D! I am in the early planning stages of a "pulse" myself! D probably created this thread cause he was tired of getting PMs and emails from ME!

WAY TO GO D! ALWAYS looking out for us!
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Old 03-22-2007, 09:28 AM  
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Would you guys like to see me pulse Oxyguno starting on monday?

That could be interesting.
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Old 03-22-2007, 02:49 PM  
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one of the things that i liked about epistane is that people have been reporting that it made their gyno smaller...would you get this affect from pulsing also?
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Old 03-22-2007, 02:52 PM  
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Very tempted to try this as I was planning a cycle net week. I would say I shutdown soon into a cycle and have difficulty not crashing while in pct so this applies to me.

You mention take the dosages close together pre/post workout before 6pm if possible. If you train at night (around 7pm) what is your suggestion? Still pre/post or earlier and pre?

Also, you mention if sensative to shutdown take an AI on off days or daily. Are we talking an OTC like 6-bromo or other?



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Old 03-22-2007, 02:59 PM  
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Quote:
Originally Posted by Sonny Crockett
Very tempted to try this as I was planning a cycle net week. I would say I shutdown soon into a cycle and have difficulty not crashing while in post cycle therapy so this applies to me.

You mention take the dosages close together pre/post workout before 6pm if possible. If you train at night (around 7pm) what is your suggestion? Still pre/post or earlier and pre?

Also, you mention if sensative to shutdown take an AI on off days or daily. Are we talking an OTC like 6-bromo or other?
Dr. D told me not to sweat taking it too late when you pulse. I work out at 8 PM, so I'm going to take it with my pre-workout meal at about 6PM. I'll also take a dose post workout as well.
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Old 03-22-2007, 03:16 PM  
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Dr. D,

I remember you talking in another thread about the possibility of using epi during post-cycle therapy in a pulsed fashion. Can this be done the same way as in a pulsed cycle? Or would one have to tweak it a little more?

thanks,
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Old 03-22-2007, 03:22 PM  
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