WARNING: This Post Contains Science Nerd Chemistry.
Here is a diagram of how test, est, dht, and andro convert.
Formestane (prohormone of 4-OHT)
4-OHT acetate (Pretend Ac is just an H, and it'll be 4-OHT)
Now then, you will notice that the only difference between andro & test (or form & 4-OHT) is that the #17 carbonyl group is replaced by a hydroxyl group, thus activating the prohormone.
Converting a carbonyl group to hydroxyl is as easy as pie: Add a metalhydride (NaBH4 or LiAlH4) and water. Unfortunately, testosterone is not that easy.
Problem You'll notice that the lower left (A) ring has a carbonyl group in both cases, and this reaction is not selective on which oxo group it attacks.
In closing, I think harnessing the potential to convert prohormones to real hormones would be........awesome. If anything it should make for an interesting chemistry discussion, and who knows, maybe we'll learn something.
:smite: thesinner
Here is a diagram of how test, est, dht, and andro convert.
Formestane (prohormone of 4-OHT)
4-OHT acetate (Pretend Ac is just an H, and it'll be 4-OHT)
Now then, you will notice that the only difference between andro & test (or form & 4-OHT) is that the #17 carbonyl group is replaced by a hydroxyl group, thus activating the prohormone.
Converting a carbonyl group to hydroxyl is as easy as pie: Add a metalhydride (NaBH4 or LiAlH4) and water. Unfortunately, testosterone is not that easy.
Problem You'll notice that the lower left (A) ring has a carbonyl group in both cases, and this reaction is not selective on which oxo group it attacks.
In closing, I think harnessing the potential to convert prohormones to real hormones would be........awesome. If anything it should make for an interesting chemistry discussion, and who knows, maybe we'll learn something.
:smite: thesinner
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