I waited till a week after stopping test to use HCG - used it for 4 weeks along with an estrogen blocker - and had no depression, and mr happy worked fine. The only side effect was lots of acne! - Back, chest, ugh - hated it - it came on at about 3 weeks and kept going for about 6 weeks more. I've been told that was because natural test came back quickly while the "other" test was still in my system. So consider a slight HCG does a week after you stop - then go a week between injections. The stuff works very well. Of course this is all hypithetical