Need som advice to reduce SHBG

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  1. Need som advice to reduce SHBG


    Hi to all as im new to this board!

    I think i have some hormone problems, indicators of this is that im 22 years old but still havent got any real beard growth, not much hair on my cheast and gentle gynecomastia. Another thing is that i have been training for about 6 months and gained in strenght but not much in muscle mass. I went to a doctor two months ago and he checked my sperm, S-Testosterone and SHBG levels. It turned out that my sperm and S-Testosterone was normal (S-Testosterone was 28 in an interval of 8-35) but my SHBG was high for my age group (49 in a range of 15-50). The doctor didnt take my concerns about the high SHBG levels (which i think is the cause of my problems) serious beacuse it was in the "normal range". I dont know what to do and i really need some advice from you on how to reduce my SHBG to get rid of my problems with sparse beard growth and such.


  2. Quote Originally Posted by deukalion
    Hi to all as im new to this board!

    I think i have some hormone problems, indicators of this is that im 22 years old but still havent got any real beard growth, not much hair on my cheast and gentle gynecomastia. Another thing is that i have been training for about 6 months and gained in strenght but not much in muscle mass. I went to a doctor two months ago and he checked my sperm, S-Testosterone and SHBG levels. It turned out that my sperm and S-Testosterone was normal (S-Testosterone was 28 in an interval of 8-35) but my SHBG was high for my age group (49 in a range of 15-50). The doctor didnt take my concerns about the high SHBG levels (which i think is the cause of my problems) serious beacuse it was in the "normal range". I dont know what to do and i really need some advice from you on how to reduce my SHBG to get rid of my problems with sparse beard growth and such.
    I understand your concern. Here's probably the best answer/suggestion I can give.

    First, let's understand what SHBG is, how it works, where it's produced, etc. Knowing about SHBG will help you make an informed decision.

    SHBG, or sex hormone-binding globulin, is a glycoprotein which binds to sex hormones such as testosterone & estradiol (estrogen). Hormones bound to SHBG cannot enter a cell & activate the cell's receptor. If you were to get a blood test & check for bound testosterone, it would be test bound to SHBG. Only free hormones (free test) are bioavailable (able to enter the cell & activate its receptor). Therefore, SHBG inhibits the functions of hormones it's bound to. SHBG is produced in the liver & released into the bloodstream. SHBG is also produced by the brain, uterus (which we don't have to worry about), placenta, & testis.

    Now that you know a little about SHBG, let's check out some possible causes.

    You can have low or high levels of SHBG (obviously the only two choices). We'll focus on causes for high since that is your case. Some things that cause high SHBG levels are pregnancy (from what I know you don't have to worry about this), hyperthyroidism, & anorexia (more common in women, so screw this one too). Now, hyperthyroidism is a possibility. When was the last time you had your T3 & T4 levels checked? If I was you, I would recommend that you go back to your doctor & recommend that he has you take a blood test to check your thyroid levels. Tell him you further researched having high SHBG levels & concluded you wanted to get your thyroid checked. He might not go for it since you fall within normal levels of SHBG in a male (even though you are higher in the normal levels). You may also want to get your estrogen levels checked because high estrogen levels can also cause a rise in SHBG.

    Now for control. There are ways to lower SHBG. You can decrease SHBG through use of insulin or IGF-1 (insulin-like growth factor 1). High androgen levels also decrease SHBG production & levels in the blood.

    Now, my opinion. Get your free test levels checked. If they are within normal ranges for your age, do nothing. If they are not, check your estrogen & thyroid hormone levels. If your doctor won't give you anything, I would begin by taking a natural testosterone enhancer/booster. This would help by increasing levels of free test. You may also want to take an anti-e to decrease the amount of estrogen active in your body. Based on your S-Test levels, I would honestly tell you that you don't have much to worry about. If you are concerned, go to your doctor first & regurgitate everything you've learned & ask him to authorize those tests. Even if he doesn't, you can still hit the labs & have them done (but you will pay full price). This should help. Once you get these done, come back & we can help you further.
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  3. Quote Originally Posted by xxtruxx1
    I understand your concern. Here's probably the best answer/suggestion I can give.

    First, let's understand what SHBG is, how it works, where it's produced, etc. Knowing about SHBG will help you make an informed decision.

    SHBG, or sex hormone-binding globulin, is a glycoprotein which binds to sex hormones such as testosterone & estradiol (estrogen). Hormones bound to SHBG cannot enter a cell & activate the cell's receptor. If you were to get a blood test & check for bound testosterone, it would be test bound to SHBG. Only free hormones (free test) are bioavailable (able to enter the cell & activate its receptor). Therefore, SHBG inhibits the functions of hormones it's bound to. SHBG is produced in the liver & released into the bloodstream. SHBG is also produced by the brain, uterus (which we don't have to worry about), placenta, & testis.

    Now that you know a little about SHBG, let's check out some possible causes.

    You can have low or high levels of SHBG (obviously the only two choices). We'll focus on causes for high since that is your case. Some things that cause high SHBG levels are pregnancy (from what I know you don't have to worry about this), hyperthyroidism, & anorexia (more common in women, so screw this one too). Now, hyperthyroidism is a possibility. When was the last time you had your T3 & T4 levels checked? If I was you, I would recommend that you go back to your doctor & recommend that he has you take a blood test to check your thyroid levels. Tell him you further researched having high SHBG levels & concluded you wanted to get your thyroid checked. He might not go for it since you fall within normal levels of SHBG in a male (even though you are higher in the normal levels). You may also want to get your estrogen levels checked because high estrogen levels can also cause a rise in SHBG.

    Now for control. There are ways to lower SHBG. You can decrease SHBG through use of insulin or IGF-1 (insulin-like growth factor 1). High androgen levels also decrease SHBG production & levels in the blood.

    Now, my opinion. Get your free test levels checked. If they are within normal ranges for your age, do nothing. If they are not, check your estrogen & thyroid hormone levels. If your doctor won't give you anything, I would begin by taking a natural testosterone enhancer/booster. This would help by increasing levels of free test. You may also want to take an anti-e to decrease the amount of estrogen active in your body. Based on your S-Test levels, I would honestly tell you that you don't have much to worry about. If you are concerned, go to your doctor first & regurgitate everything you've learned & ask him to authorize those tests. Even if he doesn't, you can still hit the labs & have them done (but you will pay full price). This should help. Once you get these done, come back & we can help you further.
    Thank you very much for the answer!
    I will go back to my doctor and make him check my T3, T4, estrogen, insulin, IGF-1 and free test levels and then return with the answers.

  4. Quote Originally Posted by deukalion
    Thank you very much for the answer!
    I will go back to my doctor and make him check my T3, T4, estrogen, insulin, IGF-1 and free test levels and then return with the answers.
    No problem, bro. Just glad I could help. Turns out this pre-med business is paying off lol.

  5. get another doctor if your free test is low and he still won't give you anything
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  6. Why not try some bulk Nettle Root, or Activate from Designer Supps? It is supposed to free up bound test from SBHG. Add some ZMA to the mix at night and see what happens.

  7. Quote Originally Posted by Mach .78
    Why not try some bulk Nettle Root, or Activate from Designer Supps? It is supposed to free up bound test from SBHG. Add some ZMA to the mix at night and see what happens.
    Hey Mach,

    Those may all be good choices, but we are having to look at him from 360 degrees before we try and say heres how you help shbg levels.If he's got a slow Thyroid and high estrogen levels, those problems should be corrected by your doc. Not supplement rats.
    My The 1 LOG: http://anabolicminds.com/forum/steroids/254164-my-one-log.html

  8. Understood.

  9. I believe growth of facial and body hair is regulated primarily by DHT, not by testosterone directly. So perhaps the problem lies in DHT metabolism or some other DHT-mediated issue.

    Get a second opinion from an endocrinologist.

    Look at the bright side... you're unlikely to go bald.

  10. Quote Originally Posted by TeamSavage
    I believe growth of facial and body hair is regulated primarily by DHT, not by testosterone directly. So perhaps the problem lies in DHT metabolism or some other DHT-mediated issue.

    Get a second opinion from an endocrinologist.

    Look at the bright side... you're unlikely to go bald.
    & he doesn't have to shave every other day!!

  11. going bald and having to shave every day is the s#$ts.

    started a beard so I'd have hair somplace on my head...LOL

  12. Nice info xxtruxx1

  13. Quote Originally Posted by deukalion
    Thank you very much for the answer!
    I will go back to my doctor and make him check my T3, T4, estrogen, insulin, IGF-1 and free test levels and then return with the answers.
    ask him if he'll do DHT also....low DHT (from a too-low number of 5AR enzymes) can also mean high SHBG (DHT preferentially binds to it over test i believe)

  14. Dude - I WISH I didn't have chest hair.

    Mine honestly started to grow when I started taking pro-hormones - while I wouldn't advocate going on a cycle JUST to get facial/body hair, keep it in mind.

  15. Quote Originally Posted by jmh80
    Dude - I WISH I didn't have chest hair.

    Mine honestly started to grow when I started taking pro-hormones - while I wouldn't advocate going on a cycle JUST to get facial/body hair, keep it in mind.
    I look like Chewbacas stunt double.
    My The 1 LOG: http://anabolicminds.com/forum/steroids/254164-my-one-log.html

  16. Not in your av (but I think that is old - back when you started the ALRI tri-lean stack, right??)

  17. Quote Originally Posted by jmh80
    Not in your av (but I think that is old - back when you started the ALRI tri-lean stack, right??)
    One must time one's photo ops when Home Depot puts weed wackers on sale. Any woman who dates must be prepared to manscape me. Otherwise I get an old girlfriend to do it!!
    My The 1 LOG: http://anabolicminds.com/forum/steroids/254164-my-one-log.html

  18. Quote Originally Posted by motiv8er
    One must time one's photo ops when Home Depot puts weed wackers on sale. Any woman who dates must be prepared to manscape me. Otherwise I get an old girlfriend to do it!!
    LOL. What a turn this thread has taken. Norelco Bodygroom for me. I used to use Nair (not for men) since my ex did it to me, but she burned my nipples once & I will never touch the stuff again just out of sheer fear. The Bodygroom is God's gift to men, besides women's little axe wound .

  19. Yeah - if you get some combination of me, Motiv8, Jay, Dsade, Dr. D, or YR in a thread - you better be watchin' out for some thread jackin!
    Cuz we 'bout to take this mutha****a off-topic boyeeee!

  20. It turned out that it was estrogen that drove up my SHBG levels. It is high but not too high just as it is with SHBG. Now im looking for a good estro-blocker. Nolvadex?

  21. Quote Originally Posted by deukalion View Post
    It turned out that it was estrogen that drove up my SHBG levels. It is high but not too high just as it is with SHBG. Now im looking for a good estro-blocker. Nolvadex?
    try anastrazole. aka arimidex

    this drug blocks the aromatase enzyme from converting testosterone into estrogen...and also has the nice little added effect of punching SHBG in the face on its way through the liver.

    good luck getting it from a doctor.


    ....or you can buy it from an online "chemical research" company for about $30 for 2 or 3 months worth.

    hint hint

    edit: it is against board rules for us to tell you exactly where you can get it, and its a big no no to even ask. just run a search-a-roo on google

  22. do you have hair on your balls yet?........just checking.

    in all seriousness you are still a youngster. at 22 i had no chest or facial hair was rail thin. as you age things begin to change. now i have too much hair and weigh 90 pounds more. give it time, you will become a man...hehhe

    a-dex or proviron may make a difference. but i'm just a supplement rat so i'd def listen to your doc.
  23. Question


    Quote Originally Posted by deukalion View Post
    It turned out that it was estrogen that drove up my SHBG levels. It is high but not too high just as it is with SHBG. Now im looking for a good estro-blocker. Nolvadex?
    Is the doctor still counseling no action?

  24. Quote Originally Posted by ripped22 View Post
    do you have hair on your balls yet?........just checking.
    Who in their right mind wants hairy balls?
    Females ain't be wantin' to put them in they mouf when they bees hairy.

  25. Quote Originally Posted by jomi822 View Post
    try anastrazole. aka arimidex

    this drug blocks the aromatase enzyme from converting testosterone into estrogen...and also has the nice little added effect of punching SHBG in the face on its way through the liver.

    good luck getting it from a doctor.


    ....or you can buy it from an online "chemical research" company for about $30 for 2 or 3 months worth.

    hint hint

    edit: it is against board rules for us to tell you exactly where you can get it, and its a big no no to even ask. just run a search-a-roo on google

    Any side effects of that in males?How much should i take if im 75kg at 180cm
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