Emu Oil and it's effects on Hairloss & inflamation

Sendo

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After BigVrunga's hairloss thread he stated he's incorporated Emu Oil and it appeared to help him. I was curious as to what information was out there regarding emu oil and was able to find the following.



[Anti-inflammatory activity and healing-promoting effects of topical application of emu oil on wound in scalded rats]
Di Yi Jun Yi Da Xue Xue Bao. 2005 Apr;25(4):407-10.
To investigate the effects of topical application of emu oil on wound healing in scalded rats. METHODS: In 144 male Wistar rats with 10%; total body surface superficial II degree scald treated on a random basis with physiological saline, povidone iodine and emu oil, respectively, the changes of the wound were observed and the wound tissue and blood samples harvested at different times after injury for evaluation of histopathological changes, total tissue water content (measured by wet:dry weight ratios), and tumor necrosis factor (TNF)-alpha levels in the wound tissue and plasma by enzyme-linked immunosorbent assay (ELISA). CONCLUSION: Emu oil has topical anti-inflammatory activity in rats with superficial II degree scald, possibly in association with decreased levels of the proinflammatory cytokines in the tissues and can promote wound healing by inhibiting local secondary inflammation.

Effect of emu oil on auricular inflammation induced with croton oil in mice.
Am J Vet Res. 1999 Dec;60(12):1558-61.
To determine the acute anti-inflammatory effects of topically applied emu oil. CONCLUSION: Topically applied emu oil significantly reduced severity of acute auricular inflammation induced by croton oil in mice.

Promotion of second intention wound healing by emu oil lotion: comparative results with furasin, polysporin, and cortisone.
Plast Reconstr Surg. 1998 Dec;102(7):2404-7.
Previous studies showed that twice-daily application of emu oil lotion (mixture of emu oil/fat, vitamin E, and botanical oil) immediately after creation of full-thickness skin defects delayed wound healing 6 days later, perhaps owing to its antiinflammatory actions. If administration was delayed for 48 hours, a two-fold promotion of wound contraction, epithelialization, and infiltration of organized granulation tissue was observed. In the present study, emu oil lotion was applied to full-thickness skin defects in rodents 24 hours after surgery. Six days postoperatively, wound contraction and infiltration of fronts of epithelialized and granulation tissue were assessed. Results indicated a two-fold promotion of all of the above parameters with emu oil lotion. No such effects were exerted by pure emu oil, furasin, cortaid, or polysporin. Data obtained indicate promise for emu oil lotion as an aid in treating full-thickness skin defects if applied after the major postinflammatory stages of wound healing have transpired.




If efficacy of emu oil can be established, it is proposed to investigate the effects of a variety of factors, such as rendering and refining procedures, the diet of the birds and the source of the oil, on the efficacy of the oil

To date the evidence for the efficacy of emu oil in wound healing has been largely anecdotal, e.g. used by aboriginals for centuries for treating burns and emu wounds heal very rapidly. The actual evidence available to support the proposal that emu oil is efficacious in wound healing and cellular regeneration is sparse and unconvincing.

A United States Patent (1) includes examples that are claimed to demonstrate that emu oil prevents scarring. The examples are, however, only anecdotal and there is no actual claim made for this application.
 

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In private studies, funded by Mount Romance, the effects of emu oil on the proliferation of cells in culture were examined. In the first study, the addition of emu oil was found to significantly (p < 0.01) increase, by up to 34%, the rate of proliferation of a fibroblast cell line. The effect was shown to be dose dependant. In the subsequent study, the addition of emu oil was found to have no effect on the rate of proliferation of keratinocytes.

In an article in a drug and cosmetic industry magazine (2) there is a report of study performed at Boston University Medical Centre using a mouse model for evaluating the biological activity of new substances on skin and hair growth. Two groups of mice had their hair removed by depilation with a wax rosin. After 24 hours one group received topically 0.1 mL of emu oil and the other 0.1 mL corn oil. The oils were then applied daily for the next 14 days. At the end of the studies samples were collected for histological examination and for the measurement of thymidine incorporation. The samples obtained from animals treated with emu oil incorporated approximately 29% more thymidine than those from the corn oil treated animals. It is not stated whether this difference was statistically significant or not.
 

Sendo

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Of particular interest was it's anti-inflammatory properties, hair stimulation properties and skin thickness.

I also saw another study that discussed more about Emu Oil having superior penetration ability. And was said that it would be an excellent canidate as an emulsifier/transport for future medicines due to the fact that it does not cause any inflammation and has superior penetration to other oils.

I wish I could find that study. Taking all that into account it sounds to me that emu oil could help transport more spironolactone to the receptors in your scalp than ordinary. Which I'm sure would prove to be beneficial to those with hair loss.

In combination with it's anti-inflammatory properties and minor healing properties, it definitely sounds like a great canidate to include in a hair loss stack.
 
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