Bromo/Gyno question

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    Bromo/Gyno question


    I was under the impression that bromo was useful for gyno reduction/prevention...but only while on cycle. But something somebody said made it sound like it could be used after the fact. So my question is: could bromo be used say a couple months after the cycle for gyno reduction??

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    I assume you are referring to bromocriptine? If so it is used to treat prolactin/progesterone related side effects usually from nandrolone cycles such as tren/npp/deca. Personally, based off scientific evidence, cabergoline is superior to it anyways.


    A Comparison of Cabergoline and Bromocriptine in the Treatment of Hyperprolactinemic Amenorrhea

    Jonathan Webster, Gabriella Piscitelli, Anna Polli, Carlo I. Ferrari, Ikram Ismail, Maurice F. Scanlon, for The Cabergoline Comparative Study Group


    ABSTRACT

    Background Cabergoline is a long-acting dopamine-agonist drug that suppresses prolactin secretion and restores gonadal function in women with hyperprolactinemic amenorrhea. We designed a study to compare its safety and efficacy with those of bromocriptine, which has been the standard therapy.

    Methods A total of 459 women with hyperprolactinemic amenorrhea were treated with either cabergoline (0.5 to 1.0 mg twice weekly) or bromocriptine (2.5 to 5.0 mg twice daily), administered in a double-blind fashion for 8 weeks and subsequently in an open fashion for 16 weeks, during which adjustments in the dose were made according to the response. Of the 459 women, 279 had microprolactinomas, 3 had macroprolactinomas, 1 had a craniopharyngioma, 167 had idiopathic hyperprolactinemia, and the remainder had an empty sella. Clinical and biochemical status was assessed at 2-week intervals for 8 weeks and monthly thereafter for a total of 6 months, with an additional assessment at 14 weeks.

    Results Stable normoprolactinemia was achieved in 186 of the 223 women treated with cabergoline (83 percent) and 138 of the 236 women treated with bromocriptine (59 percent, P<0.001). Seventy-two percent of the women treated with cabergoline and 52 percent of those treated with bromocriptine had ovulatory cycles or became pregnant during treatment (P<0.001). Amenorrhea persisted in 7 percent of the cabergoline-treated women and 16 percent of the bromocriptine-treated women. Adverse effects were recorded in 68 percent of the women taking cabergoline and 78 percent of those taking bromocriptine (P = 0.03); 3 percent discontinued taking cabergoline, and 12 percent stopped taking bromocriptine (P<0.001) because of drug intolerance. Gastrointestinal symptoms were significantly less frequent, less severe, and shorter-lived in the women treated with cabergoline.

    Conclusions Cabergoline is more effective and better tolerated than bromocriptine in women with hyperprolactinemic amenorrhea.
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    Quote Originally Posted by LakeMountD
    I assume you are referring to bromocriptine? If so it is used to treat prolactin/progesterone related side effects usually from nandrolone cycles such as tren/npp/deca. Personally, based off scientific evidence, cabergoline is superior to it anyways.
    Right, but can it be used off cycle for gyno reduction??
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    Quote Originally Posted by ((Vibe))
    Right, but can it be used off cycle for gyno reduction??
    I have never heard any success with Bromo or Caber used for gyno reduction.. I say letro is the most effective IMO..

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