Did anybody experienced loss of libido, stength, mass off cycle while using topical spiro?
the post from flybuy is interesting.. i'm curious to know if any of the other readers have has the same situation... i have been using top spiro for over a month and have no loss of libibo or other side effects. this could only occur if it made it's way through the skin and become systemic. since spiro is a diuretic, if that happed you would notice the diuretic effect.
finast doesn't work that same as spiro. spiro effects all androgens. finast simply interferes with 5ar and test doesn't become dht. it doesn't work by competing with androgens. like dutas it is classified as an azasteroid.
So if you didn't have any of the side effects, the chances are that it was not distributed systemically right? Did you use cream or solution? Maybe it becomes systemic when the carrier is a cream? But I read that a lot of people used the cream without any side effect either. Would be good to have more feedback of users.
Usually fin increases test, but it increases estrogen as well. I wouldent use that spiro stuff if somebody paid me, there is no proof it works, I hear it smells like skunked ****, and people get sides from it.
flybyu can you post a link to your test results and did you get retested after stopping the spiro to see if your test came back up?
Here's the post I made on the other 'Hair loss prevention' thread :
Important Warning About Topically Applied Spironolactone!!
Last week I ordered a bottle of Dr Richard Lee's 2% spironolactone solution from http://www.minoxidil.com
I applied it to the thinning areas of my hairline the night before as well as the morning of a blood test which included total testosterone and free testosterone. My blood test result came back as well below the normal range :
Total testosterone 5.4 nmol/L (normal range 9.5 - 35)
Calculated free testosterone 123 pmol/L (normal range 225 - 725)
Both my LH and FSH levels were in the normal range at 4 IU/L (range 1-10)
Exactly 3 weeks before I had the above blood test, I also had my testosterone levels tested. The results of this test were as follows :
Serum testosterone 16.1 nmol/L (normal range 12.4 - 34.1)
Free testosterone 53 pmol/L (normal range 31 - 100.0)
As you can see, I was in the low range of normal for testosterone in my first test, however, unlike the second test, I was still within the normal range.
I did not take any other medications or supplements over that 3 week period between the 1st and 2nd blood tests and I have not taken any drugs of any description for more than a year.
Since my T levels have fallen so dramatically in the space of just 3 weeks, I can't think of anything other than the 2% spironolactone solution that could have caused this large drop. My current blood test results shows that my blood T levels are at pre-pubescent levels!
Anyone who is thinking about using topically applied spironolactone, please don't do it. Don't believe the lies you read about topically applied spironolactone not having any systemic effects.
I think it is imperative that anyone using topical spironolactone be monitored closely for systemic side effects and blood hormone level alterations.
I have not yet had my blood test repeated, however, subjectively, I have no symtoms of low testosterone and and the spironolactone would have easily cleared my system by now. I will be having a follow-up blood test done, however, and when the results are in, I will post them here.
I don't think one should assume that every topical spironolactone product has systemic effects. It's likely that Dr Lee's 2% spironolactone liquid is absorbed more readily through the skin than his 5% cream, however, I'm not willing to try this product again after the experience I had.
Due to spironolactone's short half life, if it is only applied at night, I would imagine one's testosterone levels would return close to baseline by morning, which is why most guys don't notice much if any change in libido during the day. Having said that, who would want to have their endogenous testosterone levels lowered during sleep (the period of greatest testosterone release and muscle anabolism)? Additionally, the dramatic fluctuations in hormone levels that no doubt occur with the use of topical spironolactone cannot be at all healthy.
As far as finasteride and dutasteride are concerned, there is no way on earth I would take the stuff. Dihydrotesterone is an extremely important androgen and should not be lowered systemically. Both of these drugs elevate estrogen and have lead to gyno in some people. Dr Crisler (Swale on meso-rx) has several patients who have developed primary hypogonadism from the use of finasteride and dutasteride.
Ive used Dr.Lee's 2% Spiro solution in the past and have had zero side effects. I've really only used Spiro when on a cycle of 1test/4AD - but I used it straight through PCT with no problems.So if you didn't have any of the side effects, the chances are that it was not distributed systemically right? Did you use cream or solution? Maybe it becomes systemic when the carrier is a cream? But I read that a lot of people used the cream without any side effect either. Would be good to have more feedback of users.
FlyByU's test results are alarming, but many others have used Spiro with no ill side effects. True, it is not approved by the FDA to fight hair loss - but I am very prone to MPB and experienced no shedding even when using 1test, which is a very androgenic compound.
Just like a small number of people using Finasteride can experience negative sides, Im sure a certain number of people using Spiro topically may suffer negative side effects as well. If you do decide to use it for an extended length of time, It would probably be a good idea to consult your doctor.
No. Some users of Finasteride may experience negative sides, but many wont. I decided to start using it about 2 weeks ago @ 1mg/day, and my strength, libido, etc are all great.Wow good info., So your saying nothing helps without killing you natural test production? Would finasteride kill your natural test production?
This thread seems to be scaring people, rather than informing them about the options to fight MPB and the risks assiciated with them. True, some may experience negative side effects when using androgen blocking compounds to fight genetic AGA. Others won't experience anything at all. While some (the lucky few), will see a halt, or even a reversal of male pattern baldness.
If you're worried about losing your hair, the first step you should take is topical Azelaic Acid and Minoxidil, with Nizoral 3x per week.
If, after 6 months you arent seeing the results you're after, try adding LLLT (low level laser therapy) with a laser-comb like device. I'd even say try this first, as it seems to be quite effective...but the jury is still out there on it.
If you're certain you will keep losing your hair (have a strong genetic history of MPB, like me) if you havent seen a complete reversal of your hair loss after a couple years of minoxidil treatments, add an oral solution like Finasteride and monitor for side effects.
I'd even go so far as to say that if you're certain you're going bald, do it all right away. Finasteride, Minoxidil/AA/Nizoral,and LLLT - all of the 'proven' methods stacked together are your best bet. That's what I'm doing, and I am slowly seeing those thin spots on my head fill in - with *NO* negative sides thus far.
I've been using Propecia for about 3 years now. I have no sides. The temporal region is the same as I started it. No loss, no growth. The sides and back are thicker. I used to have an island in front with the mainland not too far away, but it's now a peninsula. I'm going to get the "research" finasteride and try it. Propecia is hella expensive.
Dangling Unit - have you tried adding minoxidil to your regimen?
I haven't. It would be too inconvenient for me. Easier to throw a pill in with my supps.Originally Posted by BigVrunga
alright... i have a question. was gonna start my own thread but then decided that there's to many hairloss threads... ok, i've never had this before but my family does have a case of the receding hairline but... now i can take my fingers and literally pull hair out of the top of my head. i'm talkin usually get like 3 hairs per pull (not a hard pull either) . it obviously stops after a while but not after the floor looks like someone just got their hair cut. this just started like 3-4 weeks ago. thats when i started liftin legs much more consistently and harder. is this due to increased test production? i will be ordering big vrunga's hair growth stack i've never used a ph or aas. just curious if anyone else has experienced this or has any incite???
I haven't had any sides with topical spiro.....but I haven't had any bloodwork done either. It does in fact smell like a skunk sack....but it certainly stops shedding while on cycle. I've used it through PCT teh same as BV and felt fine. I'm curious about bloodwork now though. Maybe that explains the crying jag when watching Fried Green Tomatoes
thanks bigvrunga... read it already tho I understand the test converting to dht then carried to scalp via the 5AR but..., i was just wondering what would have triggered this massive hair loss out of no where. don't have a fam history with balding on top and thats where i'm losin it. could i just have this test spike out of no where? i guess i should go get my levels checked or something...Originally Posted by BigVrunga
Your hair goes through cycles of growth and shedding, so it may be completely normal. A slight boost in natural testosterone wouldnt do much of anything to the hairline. Although working out and leg training can keep test levels elevated, I doubt its going to be enough to cause premature shedding, even in someone who may be prone to MPB.
I'd keep an eye on it, try not to tug on your hair too much but maybe take a picture and take another one with the same lighting a few weeks later and compare the two. If you are certain its not just a natural phase of hair shedding and you want to keep your hair, take action asap.don't have a fam history with balding on top and thats where i'm losin it
Some people lose their hair gradually over time, and for some poor folks, they can go from a nice thick mop to Mr.Clean in a year or two...
Where on top? The front, or the vertex of the head more toward the back of the head?
Seen Procede in a bunch of advertisements but it costs too much in my opinion but it claims it does not use Minoxidil or DHT blockers to be effective
OMFG!Originally Posted by Rostam
Get proscar insted, it is the same stuff and you get a lot more for the same price.Originally Posted by Dangling Unit
What?Originally Posted by getreal