Masteron & Aromatose Enzyme Affinity

[noctorum]

Drostanolone, being 5-alpha reduced, cannot form estrogen upon interaction with the aromatase enzyme yet still shows a very high affinity for it. Because it takes up so much of the aromatase enzyme, yet is refrained from actually using it by its structural make-up, it reduces the amount of estrogen formed1 from other steroids as well because there are less aromatase enzymes to be used by those compounds to form estrogen with. This made stacking with slightly aromatizing compounds such as boldenone much more bearable as it eliminated even the slight aromatisation of such substances.

Estrogen side effects (gyno, fat gain, bloat, etc.) are reduced because although masteron binds to the aromatose enzyme, it cannot actually form estrogen.

What physiological effects occur otherwise? Does the body notice an increase or a decrease in estrogen due to this? As in, would the body react in a similar way that it would to having excess estrogen otherwise (producing extra test)?