neurotic3
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The fact that almost nobody has used oral testosterone stems from its low oral bioavailability; however, taking into account that test is cheap, one might wonder whether it's worth taking test base orally.
Many people has been taking 4AD orally, which is even less effective, for only ~15% converts to test. If you were to take 1gram/day orally it should, if doses are spread evenly throughout the day, be quite similar to injecting 350mg/week.
People have been taking 1-3grams oral 4AD daily with no liver toxicity issues, haven't they? In the same way, given the fact that test isn't a 17AA either, could you take 1 gram daily without worrying about liver toxicity?
My main concern stems from this article ( http://www.endotext.org/male/male2/male2.htm ), from which I quote:
"Oral testosterone
Micronized oral testosterone has low oral bioavailability requiring high daily doses (200-400 mg) to maintain physiological testosterone levels (69). This heavy androgen load causes `prominent hepatic enzyme induction although testosterone itself is not hepatotoxic (225). Although effective in small studies, micronized oral testosterone is little used as it is not commercially available. "
By the way, given its 5% oral bioavailability I think that 400mg would give you roughly four times your physiological levels... I don't understand why the have arrived at the conclusion that you need so much in order to maintain physiological levels...
I'd mainly like to know what you think about the liver toxicity issue.
Thanks.
Many people has been taking 4AD orally, which is even less effective, for only ~15% converts to test. If you were to take 1gram/day orally it should, if doses are spread evenly throughout the day, be quite similar to injecting 350mg/week.
People have been taking 1-3grams oral 4AD daily with no liver toxicity issues, haven't they? In the same way, given the fact that test isn't a 17AA either, could you take 1 gram daily without worrying about liver toxicity?
My main concern stems from this article ( http://www.endotext.org/male/male2/male2.htm ), from which I quote:
"Oral testosterone
Micronized oral testosterone has low oral bioavailability requiring high daily doses (200-400 mg) to maintain physiological testosterone levels (69). This heavy androgen load causes `prominent hepatic enzyme induction although testosterone itself is not hepatotoxic (225). Although effective in small studies, micronized oral testosterone is little used as it is not commercially available. "
By the way, given its 5% oral bioavailability I think that 400mg would give you roughly four times your physiological levels... I don't understand why the have arrived at the conclusion that you need so much in order to maintain physiological levels...
I'd mainly like to know what you think about the liver toxicity issue.
Thanks.