Duchaine's theory of post-mediated growth
- 01-28-2005, 12:38 AM
Duchaine's theory of post-mediated growth
First off, this wasn't done by me, but I found it interesting nonetheless. Performed by uuugeboy on MMI. Here's his post.
This cycle was started on August 2004.
I am in the process of wrapping up a short 8 week bulker. I've always been interested in Duchaine's Theory of Post AR Mediated Growth and what I understand of it, that I tried it during this cycle. However, I'm not a reckless Duchaine. Much time and energy went into researching every possible aspect of this cycle theory. I am not afraid of being a guinea pig as long as I'm an informed guinea pig. For those of you who don't know, Duchaine's Theory states that at supraphysiological levels of AAS (especially test) another growth pathway opens. This is achieved by reaching levels of 4g-10g of AAS per week. Unfortunately the theory is somewhat incomplete. I say this because even though Duchaine tested this many times, he died before he had a chance to get his entire theory in writing. Information is very hard to find and the biochemistry behind the new pathway can't be found (at least I can't find it). IMO this is not what killed him although after doing it hundreds of times it certainly could have been a factor. I think what ultimately killed Duchaine is the fact that he was the world's best AAS/performance enhancing drug guinea pig. Finally things caught up with him and may he rest in peace.
Anyway, I decided to give this theory a simple test. After gathering all the research I possibly could, studying, talking with other bbers, etc, I began my experiment. My 8 week bulker was run as a standard pyramid with the middle four weeks at supraphysiological levels. I quickly ramped up to the dosages I took and then quickly came back down. I'm currently in week 8 preparing for PCT.
During the middle 4 weeks my dosages were as follows: 2.5g test enan/week, 1g sust/week, 800mg deca/week, 150mg finaprop EOD, and 50mg dbol ED. Approx 4.5-5g of AAS per week.
Results: IMO there is another growth pathway that exists at huge levels of AAS administration. My receptors had to have been supersaturated, yet my gains were incredible. For instance at week 5, I was up 35lbs. On week six I started T3 and will run it through week 9. Right now at week 8 I'm up 45lbs, and I'm continuing to grow albeit slower because of the fat burning of T3 and my down ramp.
Thoughts: I'm 100% positive that there is another growth pathway involved with high AAS administration. The short 4 week "super" cycle was hard on my body but not as hard as I expected it to be. My only side was an increase in my BP top number occasionally, which would not be uncommon under the load I was taking. I will shortly add all my ancies, supps, etc which I know helped keep everything together. I'm trying to get this all down so the bbing community has it. I wish I knew more about the biochemical pathways of the body. I'm certain the new pathway opens due to dose. I wish I could explain how the new pathway works. I wish I could explain what comprises the pathway. In the future, I would not be opposed to running this again with similar AAS (maybe a few changes) for a longer period of time. I'd like to run for 8 consecutive weeks at 6-7g per week with an up ramp and a down ramp. I'd like to run for 16 weeks. However I will not be doing another for quite sometime to let my body readjust. Currently I will still cycle, but not using Duchaine's theory (much lower dosages). I would like to wait at least 9-12 months before attempting this again. I will get blood work done this time every week. I also would like your guys'/gals' help. I need help finding a biochemical engineer or a biomedical engineer, etc who is familiar with AAS that would be interested in tracking progress during my next "super" cycle. I would like to find out and explain this new pathway.
Ancies/Supplements: During my entire cycle here are the ancies, supps, etc I'm taking (I will not include PCT because it will be pretty standard with the addition of cortisol suppression--Cymbalta (duloxetine hcl), Nolva, Femera, Remeron, Clomid, HCG, Proviron, tribus, and ZMA plus reg supps, etc): Femera 1.25mg EOD, Finasteride .5-1mg ED, Inj L-Carnitine 400mg ED, Inj Tripart 100mg ED, Inj B-Complex 38mg ED, Inj Adequan 20mg E7D, T3 25mcg weeks 6-9, Synth Gugglesterones one week (9), Cranberry juice, water, Crystal Light, Gatorade, Powerade, Glucosamine/Chondroitin 1000mg, MSM 1000mg, r-ALA 250mg 2x/day, ALCAR 450mg 2x/day, Green Tea Extract 450mg, ON Whey, Micronized Creatine, Glutamine, Glutamine peptides, Taurine 450mg 2x/day, L-Arginine 450mg 2x/day, Chromium Picolinate 200mcg, Milk Thistle 450mg, Liv-52 250mg 2x/day, Super Omega 3, 6, 9 EFAs 2000IU 2x/day, zinc 50mg 2x/day, multivit, vit c 500mg 2x/day, vit e 400IU, acidolopholous 6mg 2x/day, zanaflex 4-8mg, ultram 150mg, and HCG 250IU 2x per week.
If you have any questions feel free to ask. Also feel free to provide any and all types of feedback, etc. AND if you know of a biochemist, biomedical engineer, etc who would be interested or are a biochemist, biomedical engineer, etc I would be much obliged.
And here are the results:
I had to extend my downramp by four weeks because the body adjustment is just too much. So I ran my last four weeks with just test prop and tren ace.
Please DO NOT try this if you're a newbie or on your fifth cycle, etc, etc. This is my xxx cycle (lost count), and I went in very prepared, and I'm coming out very prepared. A great deal of research and time went into the planning and running of this cycle.
Must add bros that yes, I admit it, I did also run a little Cialis just to see what would happen during my peaks..........Jesus. All I can say is you better have multiple nymphos around at your beck and call because one nympho's (and I don't care how much of a nympho she is) accessible holes are eventually going to get tired. I'm dead serious. Either that or have a fun time punching holes in the wall or beating it to a bloody stump.
Results in total:
Gross weight gain: 45lbs
Net weight gain: 25lbs (this includes a four week T3 cycle within the bulk cycle)
I had the following tests run after PCT. All were normal with the exception of cortisol which was low (exactly where I wanted it).
Here are the tests:
Weakly Bound Test
If you have any questions let me know. Thanks bros.
- 01-28-2005, 01:06 AM
01-28-2005, 01:08 AM
01-28-2005, 10:13 AM
that's insane ... not something i would ever try aside from my concerns about having 5 grams of AAS in my body even if its only for a month, i think the health hazards associated with gaining 45 pounds in a month are too great ... with that said its pretty cool lol
01-28-2005, 10:36 AM
Intresting read. F@cking crazy though. Not to mention expensive.Every once in a while I wonder what things would be like in our comunity had he not met such an untimely death. I used to love reading his stuff.
01-28-2005, 11:32 AM
01-28-2005, 12:10 PM
01-28-2005, 01:25 PM
Salute, damn brave guy!
Thats an expensive cycle. I would volunteer to run for this cycle if everything is prepared for me. But i really can't imagine how he been through that cycle. This guy is damn hardcore and dedicated. But i wonder since he gain so much, is it possible for him to retain all the muscle he gain? If any more info pls do update, i would like to know what he will do in future.
01-28-2005, 01:35 PM
01-28-2005, 01:36 PM
he's planning something similar in about 5 months.
i've heard about this before though. that basically once you take a minimum of 2 grams of test per week, 'magic' happens. but i'm definately not game for that idea, at least not yet....
01-28-2005, 01:47 PM
Um.. you'd have to be pretty damn big to justify that sort of commitment...Originally Posted by Beelzebub
01-28-2005, 01:48 PM
01-28-2005, 02:02 PM
01-28-2005, 02:07 PM
If the "magic" refer to is u can add up one weight class with quality muscle, then its not a bad cycle after all. Just that its not cost effective and plus the unknown risks. But for my opinion, its worth it, after all this is bodybuilding.
01-28-2005, 05:34 PM
Bill roberts once stated that once you saturate the receptors. The steriod will excert its effect through another pathway with testosterone that would be through the androgen receptor since I am correct testosteron exhibits its effects through non mediated receptor pathway. Once that pathway is saturated, testosterone will work through androgen receptors.
One gram of steriods does wonders. Administering 5-10 grams, one should expect to gain much more muscle mass just of the sheer amounts. Really do not see anything spectacular with this theory.
01-28-2005, 05:44 PM
07-20-2005, 03:16 PM
What do you guys think about running a cycle like this for maybe four weeks or so You could run Prop/Tren/Dbol in doses of 2000/2000/500mg/week. I don't see how someone could run it over four weeks without having a nervous breakdown. The highest I ran a cycle was a 6 weeker consisting of Tren/Prop and the doses were 1000mg/wk tren 1000mg/w prop and I gained about 22lbs. and I actually stayed around the same bf but It was all I could take at week 4 and began my pct
07-21-2005, 12:31 AM
07-21-2005, 12:57 AM
thats a little over 70mg of dbol a day. very high, but not unheard of. it's the 100mg a day guys that i think are crazy.
as for the 2G dose. i'm gonna give it a whirl eventually for at least 10 weeks, not this year though.
07-21-2005, 01:12 AM
I hope you keep us updated on that cycle, that would be 20grams + in one cycle.
I haven't done much more than that my entire life LOL
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07-21-2005, 01:32 AM
07-21-2005, 12:24 PM
No, I wasn't running that cycle for myself just wondering what you guys' thoughts on it might be. I don't know how somebody could take so much for so long I say four weeks max with short acting esters such as tren ace. and prop/susp.
07-21-2005, 01:18 PM
not even going to attempt it until i'm able to have consistent bloodwork at least once every month.Originally Posted by CROWLER
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