Dan Duchaine and Bill Llewelyn. The following is a post from another topic, from member "EasyEJL":
"the half life is 100% irrelevant, for a pile of reasons".
"lets start with - naturally without anabolics, your low point of the day testosterone level wise is close to half what your high level is. So when you start to talk about "keeping constant blood levels" its pointless as even your natural levels arent' anywhere near constant. going past that, it may have some amount of value as to how you feel (vs how it affects anabolically) to have more stable levels, but in your case the testosterone is the base hormone covering that, so the overall androgen levels are going to stay well above normal human threshhold 24 hours a day as it is".
Beyond that, one that is interesting and only a smidgen of research has been done on it is the idea of threshhold effects. This was always a concept that made me wonder. Its easier to give something else as an example though. If you take a 2:1:1 BCAA, and put 20g total in a bunch of water, and sip it over 2 hours, it gives very little anabolic effect. If you take 10g each hour and put it down in the span of a couple minutes, it exerts a fairly big muscle protein synthesis effect. There is a certain level you have to reach to have any effect, and its not neccessarily that a certain % of the product will be lost/metabolised without adding value, but that a certain net amount of it will be in a given timespan. There was I believe 1 study done on it that was not really all that well done (number of people participating, no clear control, etc) back in the 60s that showed that with dbol effectively the first 2-3 mg you take in an hour has next to no effect. So if you were dosing it as 5mg every hour for 8 hours, you got significantly lower effectiveness out of it than taking all 40mg at once".
I then asked "EasyEJL" if he doses his orals (no matter what it is) all at once, and he replied "yes".