Orals: single dosing vs. spreadout
- 09-11-2012, 12:15 AM
- 09-11-2012, 12:53 AM
09-11-2012, 02:01 AM
"the half life is 100% irrelevant, for a pile of reasons".
"lets start with - naturally without anabolics, your low point of the day testosterone level wise is close to half what your high level is. So when you start to talk about "keeping constant blood levels" its pointless as even your natural levels arent' anywhere near constant. going past that, it may have some amount of value as to how you feel (vs how it affects anabolically) to have more stable levels, but in your case the testosterone is the base hormone covering that, so the overall androgen levels are going to stay well above normal human threshhold 24 hours a day as it is".
Beyond that, one that is interesting and only a smidgen of research has been done on it is the idea of threshhold effects. This was always a concept that made me wonder. Its easier to give something else as an example though. If you take a 2:1:1 BCAA, and put 20g total in a bunch of water, and sip it over 2 hours, it gives very little anabolic effect. If you take 10g each hour and put it down in the span of a couple minutes, it exerts a fairly big muscle protein synthesis effect. There is a certain level you have to reach to have any effect, and its not neccessarily that a certain % of the product will be lost/metabolised without adding value, but that a certain net amount of it will be in a given timespan. There was I believe 1 study done on it that was not really all that well done (number of people participating, no clear control, etc) back in the 60s that showed that with dbol effectively the first 2-3 mg you take in an hour has next to no effect. So if you were dosing it as 5mg every hour for 8 hours, you got significantly lower effectiveness out of it than taking all 40mg at once".
I then asked "EasyEJL" if he doses his orals (no matter what it is) all at once, and he replied "yes".
09-11-2012, 08:51 AM
So more research needs to be done on dosing all day, .. if u ever did SD and dose 30mgs all at once you would feel some anxiety and sort of blurred vision, increased blood pressure, that's what happened to me, its very toxic you know, also it made me feel high and real horny too lol. so I split my dose up.
09-11-2012, 09:46 AM
09-11-2012, 10:05 AM
The post that you quoted has no merit aside from the two reputable names. Name dropping does not make it any less or more valid. Data is valid.
Additionally, you have misquoted Easy. He stated "it depends" and "I think dosing orals all at once is better." His anecdotal evidence doesn't persuade me either way.
Here is some food for thought for you and your discussion. Suppose single dose is better. Would I dose before or after my workout and why or why not?
09-11-2012, 10:35 AM
like I said we all respond differently, I got some nasty back pumps too from a higher dose.Originally Posted by EasyEJL
that experience was also my secondsd cycle and (fogot to mention) I slacked a little with my support supps and my water intake, so I guess my take on dosing all at once is out the window. lol
09-11-2012, 10:41 AM
yeah, the particulars there was from someone on TRT, where they have a baseline of testosterone. I would lean more the other way of multiple doses at least for the shorter half life compounds like dbol without TRT behind it. With halo or ones that have 12+ half lifes, i'd still think single dose on waking would be best.
And then too, for me sides have been close to nonexistent on anything outside of acne and back pumps.
09-11-2012, 01:13 PM
I'm gonna try a single dose first thing every morning, currently on SD, on my 5th day of 4 weeker. see how I respond, I'm not slacking on support supps ,water intake or, diet, gymming hard and smart.. on a lean bulkOriginally Posted by EasyEJL
09-11-2012, 03:46 PM
09-11-2012, 03:51 PM
09-11-2012, 04:34 PM
09-11-2012, 04:38 PM
09-11-2012, 05:13 PM
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09-11-2012, 07:23 PM
09-11-2012, 09:37 PM
09-11-2012, 09:40 PM
From experience I'll say 50mg of var at once gave me a headache and spiked my bp a lot but splitting it up 30/20 helped with that aspect as for gains I have no idea...I'm sure the steady stream of test E has my bases covered when it comes to blood levels
09-11-2012, 11:08 PM
09-12-2012, 12:55 AM
09-12-2012, 01:18 AM
Sounds like a Clint Eastwood movie lineOriginally Posted by David Dunn
09-12-2012, 01:31 AM
09-12-2012, 04:05 AM
Sub'd for the final verdict... next thing ya know I'm gunna have to break out a mirror and a razor blade to divide up my 10mg SD caps.
09-12-2012, 10:51 AM
Just stick a cap in your bung hole for sustained release and maximum absorption.Originally Posted by MonsterTruckr
09-12-2012, 11:28 AM
09-12-2012, 12:28 PM
09-12-2012, 01:46 PM
No one can answer that question dunn, is like asking how many licks does it take to get to the center of a tootsie pop?
The world may never know.
09-12-2012, 02:08 PM
i'd say before, at least 30-60 min before. Solely because in that way you are guaranteed having the compound in your system for whatever androgenic effects it has.
Figure either you are shut down with minimal natural testosterone so the compound is your only androgen or you are running testosterone alongside and then still the two would be additive.
09-12-2012, 03:15 PM
Just for discussion sake:
When does the "anabolism" of a workout actually take place? Post workout, during recovery(?).
When does the "anabolism" of anabolics actually take place? We know they increase nutrient/protein synthesis. Again...post workout, during recovery(?).
Some have suggested that dosing it after your workout would be the most "anabolic/anabolism" window as that is when the process of recovery is and where and when nutrient/protein synthesis would be most beneficial.
Some have suggested that dosing it before your workout would be the most "advantageous" window as it can increase aggression (androgenic) and in turn increase perfromance. It does not necessarily negate the nutrient/protein synthesis but imagine it is diminished depending upon the half-life and how soon and much you can eat after workouts.
I have my opinion or preference but thought I would toss this out there.
09-12-2012, 03:19 PM
so basically if your doin SD at 20mgs(or whatever your dosing) you would take it all at once 30-60min before your session, and on off days split it..Originally Posted by EasyEJL
09-12-2012, 03:21 PM
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