I'm going through the same thing. My first cycle 200mg test e twice a week, I'm coming up on week 6. Getting some anxiety/mood swings. I really believe its the aromatization (estrogen conversion) from the long acting Esther in the test e. I took arimadex and felt sooo much better the next day. I actually started feeling the same way again today and I took the arimidex about an hour ago so hopefully tomorrow I will be back to normal! It happened twice so far about two days after I pin. I have also noticed a widening pulse pressure (128/66) I would normally be like 120/75. It seems my systolic BP is raising and my diastolic BP is lowering. Again I feel this is due to a high estrogen conversion. The good thing is when these types of things are happening, you do not need to panic because you know the reason, you are on gear. Try to stay positive and understand this is just a hormone induced mood swing and will not last or stay permanent. If it does start to last more than a few days with no relief, you need to stop. Mental health is extremely important (long term and short term)