in terms of minimizing sides/risks, there is no doubt methyls are out
imo, m-1-t is a phenomenal PH, but it carries a reasonable risk/side effect burden
heck, ANY methylated compound does
assuming one knows how to make a sterile injectable, injectables are always going to be safer, and have less risk than a methylated oral
but i agree, the question is "best for what?"
mass gains, strength, lean (dry) gains, etc?
imo, you can't go wrong with 4-ad prop, although if you are prone to gyno, you need to use a SERM with it.
unlike some 1-test options, it doesn't kill libido (i like my libido. 4-ad enhances it), it offers a good combo of strength and mass gains, and its pretty cheap
but again, it depends on what you consider important, and how you weigh relative factors