Tamoxifen Citrate Conversion

Rock Lee

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If I'm trying to make an oral solution from the TC powder, would I simply add 1 gram of TC to 50 ml polyethylene glycol, or is the process more involved than that? Also is there a difference between PEG-200 and PEG-400?

Thanks.
 

zeromagnus

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just add the TC powder to the PG and you're done...there is a difference between peg-200 and peg-400, I don't readily recall what it is, but peg-400 is used as the solvent for the harder to dissolve chemicals, like m5aa or m4ohn (though, olive oil is also used to dissolve the m4ohn)
 

Rock Lee

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Cool. So the amounts I listed (1 gram TC and 50 ml PG) are correct as well?
 

diamonddave

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Try 49ml. The powder will take up a little room.

ss
 

acecombact1

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this is maybe a stupid...............but can you dissolve the nolve in Vodka?

can i use normal PG not PG-400?
 

Rock Lee

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One more question...why do some people heat their solution where others simply shake it? Does heating it do something that shaking can't?
 
jminis

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Ok bro here we go. Save the PEG400 or 200 whatever you have for the harder to dissolve powders. Nolva is a cakewalk. Just use everclear or bacardi 151.
-Add 1g of powder to vial
-next add 49mL of everclear
-Shake a little.
-Then Boil water on stove then take it off the burner and sit bottle of solution in there and shake every 3-4minutes.
-After about 15 or so minutes it will be completely dissolved
-Bingo bango you now have 50mL of nolva @ 20mg/mL
 

diamonddave

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I'm far from an expert, but I'll try to answer some of the ???s You can actually use water (and I suppose vodka), but it won't become suspended into the liquid. You'll just have to shake it up real well before each dose. I personally am going to mix mine in either 151 or everclear, just so I don't have to pay shipping charges for the small amounts of solutions I would use. I think the PG's will actually allow the powder to dissolve in and stay somewhat suspended in the solution. I hope one of the experts jump in and correct me if I stated something that's incorrect here.


dd
 

GonnaBHuge

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this is maybe a stupid...............but can you dissolve the nolve in Vodka?

can i use normal PG not PG-400?
I recently had the same thought and tried it in Vodka. A lot of it dissolved, but there was a lot of large particles left. I was just shaking it well before I dosed it. However, after about a week the solution crashed and it looked like all of it had come out of the solution. So, I put it in the microwave for about 6 seconds, and it turned into a crystal clear solution (no particles at all). It stayed that way for several days and then crashed again this morning. So, another 5-7 seconds in the microwave and it was clear as a mountain stream once again. Hope this helps.
 

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