WUT DOES ATD STAND FOR ?
- 02-14-2009, 01:41 AM
- 02-14-2009, 02:25 AM
- 02-14-2009, 02:31 AM
From what I understand, and please correct me if I'm wrong, ATD is a type of AI. ATD is a type of AI that is known as a Suicide Inhibitor. Most that I know of don't like using ATD's due to the fact that it kills the aromitase enzyme. Another and more popular AI you should read up on is a Competitive Inhibitor. In a Comp Inhibitor the molecule just fills the active binding site of the aromatase enzyme and won't let it act on your free test. This means the body still sees the aromatase enzyme floating around and doesn't register to make more enzymes. On the other hand, with something like ATD a suicide inhibitor, the body sees the lack of enzymes (due to ATD killing them) and makes more aromatase enzymes for use. Both will work for PCT, but again most will recommend a competitive AI. Do some reseach on Advanced PCT by Anabolic Xtreme. It contains 6-Bromo which is a Comp AI. Good luck.
02-14-2009, 03:38 AM
so inhibit-e and reversitol have 1,4,6-Androstatrien-3,17-dione so its an ATD..reversitol says its has an ATD right on the supplement facts but it has 6-bromo also... novedex xt doesnt have 1,4,6-Androstatrien-3,17-dione so that makes it an AI... so if the first 2 are a suicide inhibitor then the novedex xt would be the best bet because its not an ATD...RIGHT ?
ok so reversitol is both an ATD and a AI because it has 1,4,6-Androstatrien-3,17-dione and 6-bromo.. BUT PCT ASSIST BY CEL has trans-reversitol so is that one an AI also ? so the best ones would be : novedex xt,advanced pct and pct assist because they are AI's and dont contain 1,4,6-Androstatrien-3,17-dione . so an AI doesnt destroy the aromatase enzymes in ur body it just makes the in- active..where an ATD does and can cause delayed gyno later on because once ur off the ATD your body sees tha lack of aromatase enzymes so it produces more and can cause gyno later when ur not taking anything...is that right ?
02-14-2009, 04:43 AM
So all this talk about AIs for PCT........... what are you looking at needing a PCT for?
02-14-2009, 12:24 PM
[QUOTE=BigFish80;1806047]Sounds like your starting to pick it up. Just keep in mind that ATD is just a AI. Mind you a SUICIDE AI, but still an AI. I personally don't like the suicide AIs, as they can cause a sharp drop in libido (NO ESTROGEN = NO LIBIDO) and have been known to much more influence MPB. Competitive AIs tend not to drop your estrogen so hard so these problems are minimized. Like I said I personally like aPCT by AX.
So all this talk about AIs for PCT........... what are you looking at needing a PCT for?[/QUOTE
cuz i have a bottle of inhibit-e and a bottle of novedex xt... wanna use the one thats gonna be best..so i guess its gonna be the novedex xt because it doesnt have the 1,4,6-Androstatrien-3,17-dione in it..but it got confusing because i was still researching the ATD and AI thing i read someone elses post and he listed a few otc's that he said where ATD's and novedex xt was one of them but u metioned that ATD is 1,4,6-Androstatrien-3,17-dione..novedex xt doesnt have that so im assuming thats its a COMPETITIVE AI and not an ATD .. i would and will next time get advanced pct by ax but i just dont want the novedex xt to go to waste..
02-14-2009, 12:29 PM
Key advice with ATD - LOW DOSE!
We don't yet know how long it takes the body to resynthesize ATD, but a low dose will reduce without completely killing it - thus preserving libido.
I do not ever go over 25mg every day or two.
Evolutionary Muse - Inspire to Evolve
Flawless Skin Couture - We give you the tools to make you Flawless
02-14-2009, 12:30 PM
02-14-2009, 12:30 PM
02-14-2009, 12:40 PM
ur absolutly right..just found that out and was on my way to post it...damn ! so i guess im buying a new bottle of something else..something with a 6-bromo...wut about a trans-reversitol like (cel) PCT ASSIST ? i got serm on hand but dont wanna use it if i dont have too.. so if i low dose the ATD..how should i dose it..novedex xt suggests 2 caps a day and doesnt say anything about tappering down and inhibit-e says start with 3 and tapper down to 1 on the 4th week ...
02-14-2009, 12:51 PM
02-14-2009, 01:01 PM
02-14-2009, 03:04 PM
Here ya go
Androsta- two double bonds on A-ring (1,4)
Triene- three double bonds total for molecule- two on A-ring (1,4), one on B-ring (6)
Dione- 2 ketones, one at 3rd carbon, one at 17
Alteration @ 6 produces some type of binding to aromatase- generally irreversible (suicide)- 6-bromo has a bromination @ 6, 6-oxo has an oxygenation @ 6, chlorine and flourine and maybe sulfur (works best in an epithio bond on A, but might work- sulfur is very easily glucorinidated) could also be potential choices- F and Cl might not be the best choices due to high electronegativity.....alterati on at 6 also negatively affects AR binding (poor binding affinity)- the more electronegative you go, the better the binding potential tho...
As for the dione- a reduction at 17 would yield a hydroxyl- making this structure more like boldenone (at least on the A ring- a 1,4 diene)- and the 17 reduced before the 3 keto b/c of the diene on the A ring (protected), even though 3alpha reduction is more prevalent in skeletal muscle than 17- but the en @ 6 will still keep this from binding the AR very effectively- it would probably have (and I have seen some data confirming this) more of an anti-androgenic effect than anything- it can actually compete with other circulating androgens in binding the AR.......
Dirk Tanis, BA, MSci
Chief Operating Officer, Applied Nutriceuticals
02-15-2009, 11:12 AM
02-16-2009, 10:01 AM
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