Herakleitus
New member
****, this is a repost - well, the other title wasn't helpful if you don't care to know who Cy Wilson is...
Obviously the boys at T-Mag are Biotest pimps, and so they are bound to lose sales of Mag-10 to Methyl 1-Test, since they don't carry this, but is there anything to their allegations? 25% the anabolic potency of Test prop, and 50% the adrogenic activity?! But at what dose? They also don't reference the bioassays which purportedly show this. What should we make of this?
Invalid Link Removed
"Methyl 1-Test: The True Story
Q: What is Methyl 1-test? Is it potent? Is it legally sold as a supplement or what? I'm so confused!
A: First, Methyl 1-Test isn’t even proper nomenclature. As for it being potent, Counsell, et al., found that C-17 alkylation of 17B-hydroxy-5a-androst-1-en-3-one (also incorrectly referred to as 1-Testosterone) decreased anabolic and androgenic activity in bioassays. It had about one-fourth the anabolic potency of Testosterone propionate and about half the androgenic activity.
The androgen found in MAG-10, 5a-androst-1-ene (1-Testosterone), was shown to be as androgenic as Testosterone propionate but had twice the anabolic activity. So, in reality, with this so-called methyl-1-Testosterone, you're getting the potential liver toxicity while getting much less benefit.
I think people were excited when they first heard of it as they thought, "Oh, okay, well alkylating 1-Testosterone will solve the problem of oral bioavailability and thus we'll have one kick-ass compound." In reality, adding that methyl group creates not just a methylated version of the androgen, but an entirely different molecule, period!
People need to understand that adding a methyl group or a double bond (or really any number of functional groups and atoms) creates an entirely different androgen. For instance, methandrostenolone (D-bol) only differs from Testosterone by a methyl group at the C-17 and an additional double bond between the C-1 and C-2. But can you honestly say D-bol and Testosterone impart the same effects? Even disregarding bioassays, which have demonstrated substantial differences between the two androgens, it’s still obvious to anyone who’s used them."
Obviously the boys at T-Mag are Biotest pimps, and so they are bound to lose sales of Mag-10 to Methyl 1-Test, since they don't carry this, but is there anything to their allegations? 25% the anabolic potency of Test prop, and 50% the adrogenic activity?! But at what dose? They also don't reference the bioassays which purportedly show this. What should we make of this?
Invalid Link Removed
"Methyl 1-Test: The True Story
Q: What is Methyl 1-test? Is it potent? Is it legally sold as a supplement or what? I'm so confused!
A: First, Methyl 1-Test isn’t even proper nomenclature. As for it being potent, Counsell, et al., found that C-17 alkylation of 17B-hydroxy-5a-androst-1-en-3-one (also incorrectly referred to as 1-Testosterone) decreased anabolic and androgenic activity in bioassays. It had about one-fourth the anabolic potency of Testosterone propionate and about half the androgenic activity.
The androgen found in MAG-10, 5a-androst-1-ene (1-Testosterone), was shown to be as androgenic as Testosterone propionate but had twice the anabolic activity. So, in reality, with this so-called methyl-1-Testosterone, you're getting the potential liver toxicity while getting much less benefit.
I think people were excited when they first heard of it as they thought, "Oh, okay, well alkylating 1-Testosterone will solve the problem of oral bioavailability and thus we'll have one kick-ass compound." In reality, adding that methyl group creates not just a methylated version of the androgen, but an entirely different molecule, period!
People need to understand that adding a methyl group or a double bond (or really any number of functional groups and atoms) creates an entirely different androgen. For instance, methandrostenolone (D-bol) only differs from Testosterone by a methyl group at the C-17 and an additional double bond between the C-1 and C-2. But can you honestly say D-bol and Testosterone impart the same effects? Even disregarding bioassays, which have demonstrated substantial differences between the two androgens, it’s still obvious to anyone who’s used them."
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