From what I understand, hdrol doesn't have a bad cholesterol profile like mdrol and some of the others. This is probably my biggest concern with PHs. I was on a statin about a year ago because of elevated cholesterol, and it's now in a good range. I know everyone reacts differently, but has anyone ever seen their cholesterol levels jump significantly with hdrol? I'm thinking about going back on the statin regardless, just because I tolerated it so well and studies have shown they're very safe and effective for long term use. Just wondering what others have experienced regarding hdrol and cholesterol. Would the statin affect hdrol effectiveness in any way? What about Epi?