I'm confused about this whole post-cycle stuff. There seems to be a HUGE preference for Nolva, and I'm not seeing any real back up beyond, "It's better than Clomid."
Correct me if I'm wrong, I've looked into it, but I'm far from knowledgable on the subject. (Hence the question.)
As I understand it, Nolvadex, Letrazole, and 6-Oxo are all anti-aromatase. It stops estrogen from being formed in the first place, and thus LH production is stimulated. However, all these eventually detach from the aromatase enzyme, as well as causing the body to produce more aromatase. So you get an increase in post-post-cycle estrogen.
Clomid, on the other hand, doesn't do anything to estrogen or to aromatase, it instead renders the estrogen useless by binding to the same receptors, but having a diminished estrogenic effect. According to the PDR, LH production is greatly increased. Even in normally producing adults.
The PDR does not list significant LH stimulation for the anti-aromatase drugs. (I'm guessing this means that LH won't be elevated above baseline in normally producing adults. So it's post cycle effectiveness is still in the dark for me, but anecdotal evedence suggests it works pretty well.)
Enter Exemestane. Exemestane is a suicide anti-aromatase. It permanantly occupies anti-aromatase, rendering it useless forever.
So, if you prefer anti-aromatase, why would you go with anything other than Exemestane?
But by my (admittedly shallow) research, anti-aromatase is best used during cycle, to prevent estrogenic effects. Gyno and the like. Clomid, by the accounts I've researched, is superior for returning normal hormone production. (Just lousy side effects.)
On this board, and a few others, Nolva seems king of post-cycle. Other boards warn against anti-e's post cylce, and reccomend Clomid.
So now I'm all confused as to what I should get before I start my 1-test 4-AD TD cycle.